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Lentiviral gene therapy for X-linked chronic granulomatous disease recapitulates endogenous CYBB regulation and expression

Blood, 2023-03, Vol.141 (9), p.1007-1022

2023

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Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway

Blood, 2012-04, Vol.119 (15), p.3523-3533

2012

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Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease–mediated safe harbor targeting

Blood, 2011-05, Vol.117 (21), p.5561-5572

2011

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NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

Blood, 2008-12, Vol.112 (12), p.4712-4722

2008

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NOX5 and p22phox are 2 novel regulators of human monocytic differentiation into dendritic cells

Blood, 2017-10, Vol.130 (15), p.1734-1745

2017

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NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts

Blood, 2017-10, Vol.130 (14), p.1649-1660

2017

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Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects

Blood, 2014-07, Vol.124 (4), p.590-597

2014

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Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms

Blood, 2011-10, Vol.118 (15), p.4199-4208

2011

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Human NLRP3 inflammasome activation is Nox1-4 independent

Blood, 2010-07, Vol.115 (26), p.5398-5400

2010

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Oxidized LDL activates blood platelets through CD36/NOX2–mediated inhibition of the cGMP/protein kinase G signaling cascade

Blood, 2015-04, Vol.125 (17), p.2693-2703

2015

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NOX2 is critical for heterotypic neutrophil-platelet interactions during vascular inflammation

Blood, 2015-10, Vol.126 (16), p.1952-1964

2015

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Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling

Blood, 2013-11, Vol.122 (19), p.3322-3330

2013

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Inflammatory consequences of inherited disorders affecting neutrophil function

Blood, 2019-05, Vol.133 (20), p.2130-2139

Dinauer, Mary C.

2019

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Impaired p47phox phosphorylation in neutrophils from patients with p67phox-deficient chronic granulomatous disease

Blood, 2022-04, Vol.139 (16), p.2512-2522

2022

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Heightened turnover and failed maturation of monocyte-derived macrophages in murine chronic granulomatous disease

Blood, 2022-03, Vol.139 (11), p.1707-1721

2022

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Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils

Blood, 2010-01, Vol.115 (4), p.783-791

2010

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NADPH oxidase controls pulmonary neutrophil infiltration in the response to fungal cell walls by limiting LTB4

Blood, 2020-03, Vol.135 (12), p.891-903

2020

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Platelet CD36 promotes thrombosis by activating redox sensor ERK5 in hyperlipidemic conditions

Blood, 2017-05, Vol.129 (21), p.2917-2927

2017

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Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease

Blood, 2013-03, Vol.121 (11), p.2099-2107

2013

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Angiotensin-converting enzyme enhances the oxidative response and bactericidal activity of neutrophils

Blood, 2017-07, Vol.130 (3), p.328-339

2017

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Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease

Blood, 2010-09, Vol.116 (9), p.1570-1573

2010

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Monocytic AML cells inactivate antileukemic lymphocytes: role of NADPH oxidase/gp91(phox) expression and the PARP-1/PAR pathway of apoptosis

Blood, 2012-06, Vol.119 (24), p.5832-5837

2012

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Current molecular models for NADPH oxidase regulation by Rac GTPase

Blood, 2002-10, Vol.100 (8), p.2692-2696

2002

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CD20 antibodies induce production and release of reactive oxygen species by neutrophils

Blood, 2014-06, Vol.123 (25), p.4001-4002

2014

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Lentiviral gene therapy for X-linked chronic granulomatous disease recapitulates endogenous CYBB regulation and expression

Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway

Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease–mediated safe harbor targeting

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

NOX5 and p22phox are 2 novel regulators of human monocytic differentiation into dendritic cells

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts

Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells

Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects

Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms

Human NLRP3 inflammasome activation is Nox1-4 independent

Oxidized LDL activates blood platelets through CD36/NOX2–mediated inhibition of the cGMP/protein kinase G signaling cascade

NOX2 is critical for heterotypic neutrophil-platelet interactions during vascular inflammation

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling

Inflammatory consequences of inherited disorders affecting neutrophil function

Impaired p47phox phosphorylation in neutrophils from patients with p67phox-deficient chronic granulomatous disease

Heightened turnover and failed maturation of monocyte-derived macrophages in murine chronic granulomatous disease

Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils

NADPH oxidase controls pulmonary neutrophil infiltration in the response to fungal cell walls by limiting LTB4

Platelet CD36 promotes thrombosis by activating redox sensor ERK5 in hyperlipidemic conditions

Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease

Angiotensin-converting enzyme enhances the oxidative response and bactericidal activity of neutrophils

Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease

Monocytic AML cells inactivate antileukemic lymphocytes: role of NADPH oxidase/gp91(phox) expression and the PARP-1/PAR pathway of apoptosis

Current molecular models for NADPH oxidase regulation by Rac GTPase

CD20 antibodies induce production and release of reactive oxygen species by neutrophils

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