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Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-Hydroxylation Is an In Vitro Marker of CYP3A7 Activity

Drug metabolism and disposition, 2019-06, Vol.47 (6), p.574-581

2019

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Expression and Functional Characterization of Breast Cancer-Associated Cytochrome P450 4Z1 in Saccharomyces cerevisiae

Drug metabolism and disposition, 2017-12, Vol.45 (12), p.1364-1371

2017

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Comparison of 1Beta- and 5Beta-hydroxylation of Deoxycholate and Glycodeoxycholate as In Vitro Index Reactions for Cytochrome P450 3A Activities

Drug metabolism and disposition, 2024-02, Vol.52 (2), p.126

2024

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Biosynthesis and Identification of Metabolites of Maraviroc and Their Use in Experiments to Delineate the Relative Contributions of Cytochrome P4503A4 versus 3A5

Drug metabolism and disposition, 2018-05, Vol.46 (5), p.493-502

2018

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The Hydroxylation Position Rather than Chirality Determines How Efavirenz Metabolites Activate Cytochrome P450 46A1 In Vitro

Drug metabolism and disposition, 2022-07, Vol.50 (7), p.923-930

2022

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LKY-047: First Selective Inhibitor of Cytochrome P450 2J2

Drug metabolism and disposition, 2017-07, Vol.45 (7), p.765-769

2017

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Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol

Drug metabolism and disposition, 2021-10, Vol.49 (10), p.882-891

2021

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Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry

Drug metabolism and disposition, 2019-10, Vol.47 (10), p.1195-1205

2019

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Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1'-Hydroxylation and Testosterone 6 β -Hydroxylation

Drug metabolism and disposition, 2021-03, Vol.49 (3), p.212-220

2021

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Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands

Drug metabolism and disposition, 2012-11, Vol.40 (11), p.2174

2012

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PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice

Drug metabolism and disposition, 2018-08, Vol.46 (8), p.1226-1240

2018

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Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption

Drug metabolism and disposition, 2009-08, Vol.37 (8), p.1749

2009

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Correction to "A Role for the Orphan Human Cytochrome P450 2S1 in Polyunsaturated Fatty Acid ω -1 Hydroxylation Using an Untargeted Metabolomic Approach"

Drug metabolism and disposition, 2020-03, Vol.48 (3), p.159-159

2020

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Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D 3 -3- O -Sulfate, a Major Circulating Vitamin D Metabolite in Humans

Drug metabolism and disposition, 2018-04, Vol.46 (4), p.367-379

2018

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Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo

Drug metabolism and disposition, 2015-08, Vol.43 (8), p.1267-1276

2015

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Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7

Drug metabolism and disposition, 2017-12, Vol.45 (12), p.1266-1275

2017

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Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome-Related Aqueous Metabolites in Mice

Drug metabolism and disposition, 2019-08, Vol.47 (8), p.928-940

2019

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CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity

Drug metabolism and disposition, 2016-09, Vol.44 (9), p.1480-1489

2016

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Drug interaction of efavirenz and midazolam: efavirenz activates the CYP3A-mediated midazolam 1'-hydroxylation in vitro

Drug metabolism and disposition, 2012-06, Vol.40 (6), p.1178

2012

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Species Differences of Bile Acid Redox Metabolism: Tertiary Oxidation of Deoxycholate is Conserved in Preclinical Animals

Drug metabolism and disposition, 2020-06, Vol.48 (6), p.499-507

2020

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Metabolic Profiling of the Novel Hypoxia-Inducible Factor 2 α Inhibitor PT2385 In Vivo and In Vitro

Drug metabolism and disposition, 2018-04, Vol.46 (4), p.336-345

2018

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A Role for the Orphan Human Cytochrome P450 2S1 in Polyunsaturated Fatty Acid ω -1 Hydroxylation Using an Untargeted Metabolomic Approach

Drug metabolism and disposition, 2019-11, Vol.47 (11), p.1325-1332

2019

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In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies

Drug metabolism and disposition, 2010-03, Vol.38 (3), p.448

2010

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Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors

Drug metabolism and disposition, 2017-06, Vol.45 (6), p.686-691

2017

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Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species

Drug metabolism and disposition, 2019-03, Vol.47 (3), p.283-294

2019

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Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-Hydroxylation Is an In Vitro Marker of CYP3A7 Activity

Expression and Functional Characterization of Breast Cancer-Associated Cytochrome P450 4Z1 in Saccharomyces cerevisiae

Comparison of 1Beta- and 5Beta-hydroxylation of Deoxycholate and Glycodeoxycholate as In Vitro Index Reactions for Cytochrome P450 3A Activities

Biosynthesis and Identification of Metabolites of Maraviroc and Their Use in Experiments to Delineate the Relative Contributions of Cytochrome P4503A4 versus 3A5

The Hydroxylation Position Rather than Chirality Determines How Efavirenz Metabolites Activate Cytochrome P450 46A1 In Vitro

LKY-047: First Selective Inhibitor of Cytochrome P450 2J2

Cytochrome P450-Catalyzed Metabolism of Cannabidiol to the Active Metabolite 7-Hydroxy-Cannabidiol

Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry

Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1'-Hydroxylation and Testosterone 6 β -Hydroxylation

Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands

PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice

Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption

Correction to "A Role for the Orphan Human Cytochrome P450 2S1 in Polyunsaturated Fatty Acid ω -1 Hydroxylation Using an Untargeted Metabolomic Approach"

Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D 3 -3- O -Sulfate, a Major Circulating Vitamin D Metabolite in Humans

Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo

Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7

Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome-Related Aqueous Metabolites in Mice

CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity

Drug interaction of efavirenz and midazolam: efavirenz activates the CYP3A-mediated midazolam 1'-hydroxylation in vitro

Species Differences of Bile Acid Redox Metabolism: Tertiary Oxidation of Deoxycholate is Conserved in Preclinical Animals

Metabolic Profiling of the Novel Hypoxia-Inducible Factor 2 α Inhibitor PT2385 In Vivo and In Vitro

A Role for the Orphan Human Cytochrome P450 2S1 in Polyunsaturated Fatty Acid ω -1 Hydroxylation Using an Untargeted Metabolomic Approach

In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies

Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors

Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species

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