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EZH2 inhibitors sensitize myeloma cell lines to panobinostat resulting in unique combinatorial transcriptomic changes

Oncotarget, 2018-04, Vol.9 (31), p.21930-21942

2018

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Design, synthesis and activity evaluation of quinolinone derivatives as EZH2 inhibitors

Bioorganic & medicinal chemistry letters, 2024-04, Vol.105, p.129726-129726, Article 129726

2024

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Serum EZH2 protein levels are decreased in people with multiple sclerosis: A pilot study

Human Gene, 2024-05, Vol.40, Article 201278

2024

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AML-192: Enhancer of Zeste Homolog 2 (EZH2) in COVID-19-Positive Acute Myeloid Leukemia

Clinical lymphoma, myeloma and leukemia, 2021-09, Vol.21, p.S289-S290

2021

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AML-137: Expression of Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Gene (EZH2) In Acute Myeloid Leukemia

Clinical lymphoma, myeloma and leukemia, 2021-09, Vol.21, p.S282-S283

2021

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LncRNA TINCR attenuates cardiac hypertrophy by epigenetically silencing CaMKII

Oncotarget, 2017-07, Vol.8 (29), p.47565-47573

2017

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EZH2 Promotes Glioma Cell Proliferation, Invasion, and Migration via Mir-142-3p/KCNQ1OT1/HMGB3 Axis : Running Title: EZH2 Promotes Glioma cell Malignant Behaviors

Molecular neurobiology, 2024-04

2024

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USP7 inhibits TIMP2 by up-regulating the expression of EZH2 to activate the NF-κB/PD-L1 axis to promote the development of cervical cancer

Cellular signalling, 2022-08, Vol.96, p.110351-110351, Article 110351

2022

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Transcription suppression of GABARAP mediated by lncRNA XIST-EZH2 interaction triggers caspase-11-dependent inflammatory injury in ulcerative colitis

Immunobiology (1979), 2024-05, Vol.229 (3), p.152796-152796, Article 152796

2024

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Attenuated Salmonella-delivered PD-1 siRNA enhances the antitumor effects of EZH2 inhibitors in colorectal cancer

International immunopharmacology, 2023-11, Vol.124, p.110918-110918, Article 110918

2023

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Cross-species analyses unravel the complexity of H3K27me3 and H4K20me3 in the context of neural stem progenitor cells

Neuroepigenetics, 2016-06, Vol.6, p.10-25

2016

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EZH2: a novel target for cancer treatment

Journal of hematology and oncology, 2020-07, Vol.13 (1), p.104-12, Article 104

2020

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The EZH2 inhibitor GSK343 suppresses cancer stem-like phenotypes and reverses mesenchymal transition in glioma cells

Oncotarget, 2017-11, Vol.8 (58), p.98348-98359

2017

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Novel insights of EZH2-mediated epigenetic modifications in degenerative musculoskeletal diseases

Ageing research reviews, 2023-09, Vol.90, p.102034-102034, Article 102034

2023

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Telomere dysfunction alters intestinal stem cell dynamics to promote cancer

Developmental cell, 2024-03

2024

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The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

Oncotarget, 2018-03, Vol.9 (21), p.15512-15525

2018

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Enhancer of Zeste Homolog 2 Inhibition Induces HLA Class I Re-Expression in Merkel Cell Carcinoma

Journal of investigative dermatology, 2023-12, p.S0022-202X(23)03121-4

2023

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ABCL-211: Mutations at Codon 641 of Exon 16 of EZH2 in Circulating and Tumor DNA: A Biomarker for Relapse in Patients with Diffuse Large B-Cell Lymphoma Treated with the R-CHOP Regimen

Clinical lymphoma, myeloma and leukemia, 2021-09, Vol.21, p.S382-S382

2021

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Paeoniflorin promotes PPARγ expression to suppress HSCs activation by inhibiting EZH2-mediated histone H3K27 trimethylation

Phytomedicine (Stuttgart), 2024-06, Vol.128, p.155477-155477, Article 155477

2024

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EZH2-mediated development of therapeutic resistance in cancer

Cancer letters, 2024-04, Vol.586, p.216706-216706, Article 216706

2024

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Circular RNA circ-PRMT5 facilitates non-small cell lung cancer proliferation through upregulating EZH2 via sponging miR-377/382/498

Gene, 2019-12, Vol.720, p.144099-144099, Article 144099

2019

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RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer

Oncotarget, 2015-02, Vol.6 (4), p.2263-2276

2015

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Inhibition of EZH2 attenuates inhibitory synaptic transmission via the pro-inflammatory pathway in rats

Neuropharmacology, 2020-07, Vol.171, p.108101-108101, Article 108101

2020

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Suppression of EZH2 inhibits TGF-β1-induced EMT in human retinal pigment epithelial cells

Experimental eye research, 2022-09, Vol.222, p.109158-109158, Article 109158

2022

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Celastrol attenuates diabetic nephropathy by upregulating SIRT1-mediated inhibition of EZH2related wnt/β-catenin signaling

International immunopharmacology, 2023-09, Vol.122, p.110584-110584, Article 110584

2023

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EZH2 inhibitors sensitize myeloma cell lines to panobinostat resulting in unique combinatorial transcriptomic changes

Design, synthesis and activity evaluation of quinolinone derivatives as EZH2 inhibitors

Serum EZH2 protein levels are decreased in people with multiple sclerosis: A pilot study

AML-192: Enhancer of Zeste Homolog 2 (EZH2) in COVID-19-Positive Acute Myeloid Leukemia

AML-137: Expression of Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Gene (EZH2) In Acute Myeloid Leukemia

LncRNA TINCR attenuates cardiac hypertrophy by epigenetically silencing CaMKII

EZH2 Promotes Glioma Cell Proliferation, Invasion, and Migration via Mir-142-3p/KCNQ1OT1/HMGB3 Axis : Running Title: EZH2 Promotes Glioma cell Malignant Behaviors

USP7 inhibits TIMP2 by up-regulating the expression of EZH2 to activate the NF-κB/PD-L1 axis to promote the development of cervical cancer

Transcription suppression of GABARAP mediated by lncRNA XIST-EZH2 interaction triggers caspase-11-dependent inflammatory injury in ulcerative colitis

Attenuated Salmonella-delivered PD-1 siRNA enhances the antitumor effects of EZH2 inhibitors in colorectal cancer

Cross-species analyses unravel the complexity of H3K27me3 and H4K20me3 in the context of neural stem progenitor cells

EZH2: a novel target for cancer treatment

The EZH2 inhibitor GSK343 suppresses cancer stem-like phenotypes and reverses mesenchymal transition in glioma cells

Novel insights of EZH2-mediated epigenetic modifications in degenerative musculoskeletal diseases

Telomere dysfunction alters intestinal stem cell dynamics to promote cancer

The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

Enhancer of Zeste Homolog 2 Inhibition Induces HLA Class I Re-Expression in Merkel Cell Carcinoma

ABCL-211: Mutations at Codon 641 of Exon 16 of EZH2 in Circulating and Tumor DNA: A Biomarker for Relapse in Patients with Diffuse Large B-Cell Lymphoma Treated with the R-CHOP Regimen

Paeoniflorin promotes PPARγ expression to suppress HSCs activation by inhibiting EZH2-mediated histone H3K27 trimethylation

EZH2-mediated development of therapeutic resistance in cancer

Circular RNA circ-PRMT5 facilitates non-small cell lung cancer proliferation through upregulating EZH2 via sponging miR-377/382/498

RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer

Inhibition of EZH2 attenuates inhibitory synaptic transmission via the pro-inflammatory pathway in rats

Suppression of EZH2 inhibits TGF-β1-induced EMT in human retinal pigment epithelial cells

Celastrol attenuates diabetic nephropathy by upregulating SIRT1-mediated inhibition of EZH2related wnt/β-catenin signaling

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