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Cannabis and Cannabinoids: Kinetics and Interactions

The American journal of medicine, 2019-11, Vol.132 (11), p.1266-1270

2019

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The impact of legacy and novel perfluoroalkyl substances on human cytochrome P450: An in vitro study on the inhibitory potential and underlying mechanisms

Toxicology (Amsterdam), 2022-02, Vol.468, p.153116-153116, Article 153116

2022

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Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids

Toxicology letters, 2020-02, Vol.319, p.148-154

2020

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Pharmacokinetics and pharmacodynamics of cytochrome P450 inhibitors for HIV treatment

Expert opinion on drug metabolism & toxicology, 2019-05, Vol.15 (5), p.417-427

2019

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In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug–drug interactions

Pharmacological reports, 2020-06, Vol.72 (3), p.612-621

2020

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Pharmacogenomics of triazole antifungal agents: implications for safety, tolerability and efficacy

Expert opinion on drug metabolism & toxicology, 2017-11, Vol.13 (11), p.1135-1146

2017

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New azole derivatives showing antimicrobial effects and their mechanism of antifungal activity by molecular modeling studies

European journal of medicinal chemistry, 2017-04, Vol.130, p.124-138

2017

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In vitro characterization of the furin inhibitor MI-1851: Albumin binding, interaction with cytochrome P450 enzymes and cytotoxicity

Biomedicine & pharmacotherapy, 2022-07, Vol.151, p.113124-113124, Article 113124

2022

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Evaluation of potential herb-drug interactions based on the effect of Suxiao Jiuxin Pill on CYP450 enzymes and transporters

Journal of ethnopharmacology, 2021-11, Vol.280, p.114408, Article 114408

2021

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Unravelling the Molecular Determinants of Bee Sensitivity to Neonicotinoid Insecticides

Current biology, 2018-04, Vol.28 (7), p.1137-1143.e5

2018

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Potential drug targets in the Mycobacterium tuberculosis cytochrome P450 system

Journal of inorganic biochemistry, 2018-03, Vol.180, p.235-245

Ortiz de Montellano, Paul R.

2018

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Molecular determinant of substrate binding and specificity of cytochrome P450 2J2

Scientific reports, 2020-12, Vol.10 (1), p.22267-22267, Article 22267

2020

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In Vitro and In Vivo Drug-Drug Interaction Study of the Effects of Ivermectin and Oxantel Pamoate on Tribendimidine

Antimicrobial agents and chemotherapy, 2019-01, Vol.63 (1)

2019

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Drug-drug interactions that interfere with statin metabolism

Expert opinion on drug metabolism & toxicology, 2015-01, Vol.11 (9), p.1435-1447

2015

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Pharmaceutical Excipients and Drug Metabolism: A Mini-Review

International journal of molecular sciences, 2020-11, Vol.21 (21), p.8224

2020

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Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study

Cancer prevention research (Philadelphia, Pa.), 2010-09, Vol.3 (9), p.1168-1175

2010

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Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure

Emerging infectious diseases, 2009-07, Vol.15 (7), p.1068-1076

2009

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Drug–Drug Interaction Potential of Darolutamide: In Vitro and Clinical Studies

European journal of drug metabolism and pharmacokinetics, 2019-12, Vol.44 (6), p.747-759

2019

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Microsomal cytochrome P450 as a target for drug discovery and repurposing

Drug metabolism reviews, 2017-01, Vol.49 (1), p.1-17

2017

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Interactions between tamoxifen and antidepressants via cytochrome P450 2D6

The journal of clinical psychiatry, 2009-12, Vol.70 (12), p.1688

2009

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Active Site Hydrogen Bonding Induced in Cytochrome P450cam by Effector Putidaredoxin

Biochemistry (Easton), 2021-06, Vol.60 (21), p.1699-1707

2021

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Evaluation of in vitro inhibition and induction of cytochrome P450 activities by hydrolyzed ginkgolides

Journal of ethnopharmacology, 2014-12, Vol.158, p.132-139

2014

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Cytochrome P450 (CYP) epoxygenases as potential targets in the management of impaired diabetic wound healing

Laboratory investigation, 2017-07, Vol.97 (7), p.782

2017

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Inhibitory Effects of Quercetin and Its Main Methyl, Sulfate, and Glucuronic Acid Conjugates on Cytochrome P450 Enzymes, and on OATP, BCRP and MRP2 Transporters

Nutrients, 2020-07, Vol.12 (8), p.2306

2020

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Aidi injection altered the activity of CYP2D4, CYP1A2, CYP2C19, CYP3A2, CYP2E1 and CYP2C11 in normal and diethylnitrosamine-induced hepatocellular carcinoma in rats

Journal of ethnopharmacology, 2022-03, Vol.286, p.114930-114930, Article 114930

2022

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Cannabis and Cannabinoids: Kinetics and Interactions

The impact of legacy and novel perfluoroalkyl substances on human cytochrome P450: An in vitro study on the inhibitory potential and underlying mechanisms

Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids

Pharmacokinetics and pharmacodynamics of cytochrome P450 inhibitors for HIV treatment

In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug–drug interactions

Pharmacogenomics of triazole antifungal agents: implications for safety, tolerability and efficacy

New azole derivatives showing antimicrobial effects and their mechanism of antifungal activity by molecular modeling studies

In vitro characterization of the furin inhibitor MI-1851: Albumin binding, interaction with cytochrome P450 enzymes and cytotoxicity

Evaluation of potential herb-drug interactions based on the effect of Suxiao Jiuxin Pill on CYP450 enzymes and transporters

Unravelling the Molecular Determinants of Bee Sensitivity to Neonicotinoid Insecticides

Potential drug targets in the Mycobacterium tuberculosis cytochrome P450 system

Molecular determinant of substrate binding and specificity of cytochrome P450 2J2

In Vitro and In Vivo Drug-Drug Interaction Study of the Effects of Ivermectin and Oxantel Pamoate on Tribendimidine

Drug-drug interactions that interfere with statin metabolism

Pharmaceutical Excipients and Drug Metabolism: A Mini-Review

Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study

Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure

Drug–Drug Interaction Potential of Darolutamide: In Vitro and Clinical Studies

Microsomal cytochrome P450 as a target for drug discovery and repurposing

Interactions between tamoxifen and antidepressants via cytochrome P450 2D6

Active Site Hydrogen Bonding Induced in Cytochrome P450cam by Effector Putidaredoxin

Evaluation of in vitro inhibition and induction of cytochrome P450 activities by hydrolyzed ginkgolides

Cytochrome P450 (CYP) epoxygenases as potential targets in the management of impaired diabetic wound healing

Inhibitory Effects of Quercetin and Its Main Methyl, Sulfate, and Glucuronic Acid Conjugates on Cytochrome P450 Enzymes, and on OATP, BCRP and MRP2 Transporters

Aidi injection altered the activity of CYP2D4, CYP1A2, CYP2C19, CYP3A2, CYP2E1 and CYP2C11 in normal and diethylnitrosamine-induced hepatocellular carcinoma in rats

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