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Cenicriviroc Treatment for Adults With Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study

Hepatology (Baltimore, Md.), 2020-09, Vol.72 (3), p.892-905

2020

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Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis

PloS one, 2016-06, Vol.11 (6), p.e0158156

2016

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Maraviroc: a review of its use in HIV infection and beyond

Drug design, development and therapy, 2015-01, Vol.9 (default), p.5447-5468

2015

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A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action

European journal of pharmaceutical sciences, 2013-02, Vol.48 (3), p.406-415

2013

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Activity and structural analysis of GRL-117C: a novel small molecule CCR5 inhibitor active against R5-tropic HIV-1s

Scientific reports, 2019-03, Vol.9 (1), p.4828, Article 4828

2019

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Chemokine receptor CCR5 antagonist maraviroc: medicinal chemistry and clinical applications

Current topics in medicinal chemistry, 2014-09, Vol.14 (13), p.1504

2014

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Function-Oriented Development of CXCR4 Antagonists as Selective Human Immunodeficiency Virus (HIV)‑1 Entry Inhibitors

Journal of medicinal chemistry, 2015-02, Vol.58 (3), p.1452-1465

2015

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How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher?

Biochemical journal, 2017-05, Vol.474 (10), p.1559-1577

2017

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A randomized, placebo‐controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis

Hepatology (Baltimore, Md.), 2018-05, Vol.67 (5), p.1754-1767

2018

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CCR5 Blockade in Inflammatory PML and PML-IRIS Associated With Chronic Inflammatory Diseases' Treatments

Neurology : neuroimmunology & neuroinflammation, 2022-01, Vol.9 (1)

2022

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Asymmetric Synthesis of (−)-Brevipolide H through Cyclopropanation of the α,β-Unsaturated Ketone

Organic letters, 2014-10, Vol.16 (20), p.5328-5331

2014

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Design, syntheses, and characterization of piperazine based chemokine receptor CCR5 antagonists as anti prostate cancer agents

Bioorganic & medicinal chemistry letters, 2014-05, Vol.24 (10), p.2319-2323

2014

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Incompatible Natures of the HIV-1 Envelope in Resistance to the CCR5 Antagonist Cenicriviroc and to Neutralizing Antibodies

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.437-450

2016

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Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists

Organic & biomolecular chemistry, 2015-01, Vol.13 (8), p.2407-2422

2015

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Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

Immunity (Cambridge, Mass.), 2017-06, Vol.46 (6), p.1005-1017.e5

2017

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Brief Report: Pharmacokinetic/Pharmacodynamic Investigation of Single-Dose Oral Maraviroc in the Context of HIV-1 Pre-exposure Prophylaxis

Journal of acquired immune deficiency syndromes (1999), 2016-11, Vol.73 (3), p.252

2016

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Targeting CCR5 as a Component of an HIV-1 Therapeutic Strategy

Frontiers in immunology, 2022-01, Vol.12, p.816515

2022

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Maraviroc reduces neuropathic pain through polarization of microglia and astroglia – Evidence from in vivo and in vitro studies

Neuropharmacology, 2016-09, Vol.108, p.207-219

2016

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The efficacy and safety of maraviroc addition to a stable antiretroviral regimen in subjects with suppressed plasma HIV-RNA is not influenced by age

AIDS research and human retroviruses, 2015-09, Vol.31 (9), p.893

2015

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Inhibition of Inflammatory and Neuropathic Pain by Targeting a Mu Opioid Receptor/Chemokine Receptor5 Heteromer (MOR-CCR5)

Journal of medicinal chemistry, 2015-11, Vol.58 (21), p.8647-8657

2015

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Co-receptor signaling in the pathogenesis of neuroHIV

Retrovirology, 2021-08, Vol.18 (1), p.24-24, Article 24

2021

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Targeting chemokine receptors for HIV: past, present and future

Future medicinal chemistry, 2015-01, Vol.7 (17), p.2311-2315

Fricker, Simon P

2015

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Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES

Journal of controlled release, 2019-03, Vol.298, p.1-11

2019

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Clinical evidence for a lack of cross-resistance between temsavir and ibalizumab or maraviroc

AIDS (London), 2022-01, Vol.36 (1), p.11-18

2022

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A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands

British journal of pharmacology, 2014-07, Vol.171 (14), p.3364-3375

2014

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Cenicriviroc Treatment for Adults With Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study

Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis

Maraviroc: a review of its use in HIV infection and beyond

A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action

Activity and structural analysis of GRL-117C: a novel small molecule CCR5 inhibitor active against R5-tropic HIV-1s

Chemokine receptor CCR5 antagonist maraviroc: medicinal chemistry and clinical applications

Function-Oriented Development of CXCR4 Antagonists as Selective Human Immunodeficiency Virus (HIV)‑1 Entry Inhibitors

How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher?

A randomized, placebo‐controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis

CCR5 Blockade in Inflammatory PML and PML-IRIS Associated With Chronic Inflammatory Diseases' Treatments

Asymmetric Synthesis of (−)-Brevipolide H through Cyclopropanation of the α,β-Unsaturated Ketone

Design, syntheses, and characterization of piperazine based chemokine receptor CCR5 antagonists as anti prostate cancer agents

Incompatible Natures of the HIV-1 Envelope in Resistance to the CCR5 Antagonist Cenicriviroc and to Neutralizing Antibodies

Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists

Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

Brief Report: Pharmacokinetic/Pharmacodynamic Investigation of Single-Dose Oral Maraviroc in the Context of HIV-1 Pre-exposure Prophylaxis

Targeting CCR5 as a Component of an HIV-1 Therapeutic Strategy

Maraviroc reduces neuropathic pain through polarization of microglia and astroglia – Evidence from in vivo and in vitro studies

The efficacy and safety of maraviroc addition to a stable antiretroviral regimen in subjects with suppressed plasma HIV-RNA is not influenced by age

Inhibition of Inflammatory and Neuropathic Pain by Targeting a Mu Opioid Receptor/Chemokine Receptor5 Heteromer (MOR-CCR5)

Co-receptor signaling in the pathogenesis of neuroHIV

Targeting chemokine receptors for HIV: past, present and future

Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES

Clinical evidence for a lack of cross-resistance between temsavir and ibalizumab or maraviroc

A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands

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