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Expansion of the CRISPR-Cas9 genome targeting space through the use of H1 promoter-expressed guide RNAs

Nature communications, 2014-08, Vol.5 (1), p.4516-4516, Article 4516

2014

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Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (6), p.E507-E516

2013

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Construction of human activity‐based phosphorylation networks

Molecular systems biology, 2013, Vol.9 (1), p.655-n/a

2013

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Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells

PloS one, 2016-03, Vol.11 (3), p.e0150758-e0150758

2016

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Crx, a Novel Otx-like Paired-Homeodomain Protein, Binds to and Transactivates Photoreceptor Cell-Specific Genes

Neuron (Cambridge, Mass.), 1997-11, Vol.19 (5), p.1017-1030

1997

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Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors

BMC bioinformatics, 2007-11, Vol.8 (1), p.437-437, Article 437

2007

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Analysis of the VMD2 Promoter and Implication of E-box Binding Factors in Its Regulation

The Journal of biological chemistry, 2004-04, Vol.279 (18), p.19064-19073

2004

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Expression of rod-derived cone viability factor: dual role of CRX in regulating promoter activity and cell-type specificity

PloS one, 2010-10, Vol.5 (10), p.e13075

2010

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Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

Human molecular genetics, 2014-11, Vol.23 (21), p.5827-5837

2014

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A Pineal Regulatory Element (PIRE) Mediates Transactivation by the Pineal/Retina-Specific Transcription Factor CRX

Proceedings of the National Academy of Sciences - PNAS, 1998-02, Vol.95 (4), p.1876-1881

1998

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Rin, a Neuron-Specific and Calmodulin-Binding Small G-Protein, and Rit Define a Novel Subfamily of Ras Proteins

The Journal of neuroscience, 1996-11, Vol.16 (21), p.6784-6794

1996

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Cloning and Characterization of a Human β,β-Carotene-15, 15′-Dioxygenase That Is Highly Expressed in the Retinal Pigment Epithelium

Genomics (San Diego, Calif.), 2001-03, Vol.72 (2), p.193-202

2001

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QRX, a novel homeobox gene, modulates photoreceptor gene expression

Human molecular genetics, 2004-05, Vol.13 (10), p.1025-1040

2004

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Functional analysis of the rod photoreceptor cGMP phosphodiesterase alpha-subunit gene promoter: Nrl and Crx are required for full transcriptional activity

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.19800-19807

2004

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Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration

Neuron (Cambridge, Mass.), 1997-12, Vol.19 (6), p.1329-1336

1997

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Cloning and Characterization of a Secreted Frizzled-Related Protein that is Expressed by the Retinal Pigment Epithelium

Human molecular genetics, 1999-04, Vol.8 (4), p.575-583

1999

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Functional analysis of cone–rod homeobox (CRX) mutations associated with retinal dystrophy

Human molecular genetics, 2002-04, Vol.11 (8), p.873-884

2002

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Functional Domains of the Cone-Rod Homeobox (CRX) Transcription Factor

The Journal of biological chemistry, 2000-11, Vol.275 (47), p.37264-37270

2000

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The bZIP Transcription Factor Nrl Stimulates Rhodopsin Promoter Activity in Primary Retinal Cell Cultures

The Journal of biological chemistry, 1996-11, Vol.271 (47), p.29612-29618

1996

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Ret 4, a Positive Acting Rhodopsin Regulatory Element Identified Using a Bovine Retina in Vitro Transcription System

The Journal of biological chemistry, 1996-11, Vol.271 (45), p.28549-28557

1996

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Mammalian Homolog of Drosophila retinal degeneration B Rescues the Mutant Fly Phenotype

The Journal of neuroscience, 1997-08, Vol.17 (15), p.5881-5890

1997

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RER, an Evolutionarily Conserved Sequence Upstream of the Rhodopsin Gene, Has Enhancer Activity ()

The Journal of biological chemistry, 1996-02, Vol.271 (5), p.2667-2675

1996

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The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation

The Journal of biological chemistry, 2000-09, Vol.275 (38), p.29794-29799

2000

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Functional Dissection of the Promoter of the Interphotoreceptor Retinoid-Binding Protein Gene: The Cone-Rod-Homeobox Element Is Essential for Photoreceptor-Specific Expression In Vivo

Journal of biochemistry (Tokyo), 1999-06, Vol.125 (6), p.1189-1199

1999

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The Basic Motif-Leucine Zipper Transcription Factor Nrl can Positively Regulate Rhodopsin Gene Expression

Proceedings of the National Academy of Sciences - PNAS, 1996-01, Vol.93 (1), p.191-195

1996

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Expansion of the CRISPR-Cas9 genome targeting space through the use of H1 promoter-expressed guide RNAs

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration

Construction of human activity‐based phosphorylation networks

Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells

Crx, a Novel Otx-like Paired-Homeodomain Protein, Binds to and Transactivates Photoreceptor Cell-Specific Genes

Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors

Analysis of the VMD2 Promoter and Implication of E-box Binding Factors in Its Regulation

Expression of rod-derived cone viability factor: dual role of CRX in regulating promoter activity and cell-type specificity

Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

A Pineal Regulatory Element (PIRE) Mediates Transactivation by the Pineal/Retina-Specific Transcription Factor CRX

Rin, a Neuron-Specific and Calmodulin-Binding Small G-Protein, and Rit Define a Novel Subfamily of Ras Proteins

Cloning and Characterization of a Human β,β-Carotene-15, 15′-Dioxygenase That Is Highly Expressed in the Retinal Pigment Epithelium

QRX, a novel homeobox gene, modulates photoreceptor gene expression

Functional analysis of the rod photoreceptor cGMP phosphodiesterase alpha-subunit gene promoter: Nrl and Crx are required for full transcriptional activity

Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration

Cloning and Characterization of a Secreted Frizzled-Related Protein that is Expressed by the Retinal Pigment Epithelium

Functional analysis of cone–rod homeobox (CRX) mutations associated with retinal dystrophy

Functional Domains of the Cone-Rod Homeobox (CRX) Transcription Factor

The bZIP Transcription Factor Nrl Stimulates Rhodopsin Promoter Activity in Primary Retinal Cell Cultures

Ret 4, a Positive Acting Rhodopsin Regulatory Element Identified Using a Bovine Retina in Vitro Transcription System

Mammalian Homolog of Drosophila retinal degeneration B Rescues the Mutant Fly Phenotype

RER, an Evolutionarily Conserved Sequence Upstream of the Rhodopsin Gene, Has Enhancer Activity ()

The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation

Functional Dissection of the Promoter of the Interphotoreceptor Retinoid-Binding Protein Gene: The Cone-Rod-Homeobox Element Is Essential for Photoreceptor-Specific Expression In Vivo

The Basic Motif-Leucine Zipper Transcription Factor Nrl can Positively Regulate Rhodopsin Gene Expression

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