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Synthesis and Structure–Activity Relationships of Novel Zwitterionic Compounds as Peroxisome Proliferator Activated Receptor α/γ Dual Agonists with Improved Physicochemical Properties

Chemical and Pharmaceutical Bulletin, 2013/12/01, Vol.61(12), pp.1248-1263

2013

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Discovery of N-[(1 R,2 S,5 S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4- c]pyridine-2-carboxamide hydrochloride: A novel, potent and orally active direct inhibitor of factor Xa

Bioorganic & medicinal chemistry, 2009-02, Vol.17 (3), p.1193-1206

2009

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Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (16), p.4683-4688

2007

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Suppressive Effect of β-Endorphin on Body Shaking Response to Ice Water Immersion and Synergistic Action of Vasoactive Intestinal Peptide on β-Endorphin in Anesthetized Rats

The Japanese Journal of Physiology, 1983, Vol.33(5), pp.821-826

1983

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Hypermotility induced by vasoactive intestinal peptide in the rat: Its reciprocal action to cholecystokinin octapeptide

Peptides (New York, N.Y. : 1980), 1985-01, Vol.6 (1), p.53-57

1985

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Behavioral effects of thyrotropin releasing hormone in frontal decorticated rats

Peptides (New York, N.Y. : 1980), 1984-01, Vol.5 (5), p.899-903

1984

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Interaction of cholecystokinin with vasoactive intestinal peptide in body shaking response to ice-water immersion in rats

Neuroscience letters, 1983-10, Vol.40 (3), p.299-302

1983

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Potentiation of beta-endorphin effects by cholecystokinin antiserum in rats

Canadian journal of physiology and pharmacology, 1985-01, Vol.63 (1), p.81

1985

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Social isolation-induced aggression potentiates anxiety and depressive-like behavior in male mice subjected to unpredictable chronic mild stress

PloS one, 2011-06, Vol.6 (6), p.e20955-e20955

2011

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Heterozygous Disruption of Autism susceptibility candidate 2 Causes Impaired Emotional Control and Cognitive Memory

PloS one, 2015-12, Vol.10 (12), p.e0145979-e0145979

2015

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Loss of SMAD4 Promotes Lung Metastasis of Colorectal Cancer by Accumulation of CCR1+ Tumor-Associated Neutrophils through CCL15-CCR1 Axis

Clinical cancer research, 2017-02, Vol.23 (3), p.833-844

2017

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Altered dendritic morphology of Purkinje cells in Dyt1 ΔGAG knock-in and purkinje cell-specific Dyt1 conditional knockout mice

PloS one, 2011-03, Vol.6 (3), p.e18357-e18357

2011

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Arachidonic acid drives postnatal neurogenesis and elicits a beneficial effect on prepulse inhibition, a biological trait of psychiatric illnesses

PloS one, 2009-04, Vol.4 (4), p.e5085-e5085

2009

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Brg1 is required to maintain colorectal cancer stem cells

The Journal of pathology, 2021-11, Vol.255 (3), p.257-269

2021

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Lineage tracing and targeting of IL17RB⁺ tuft cell-like human colorectal cancer stem cells

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (26), p.12996-13005

2019

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Locally Produced BDNF Promotes Sclerotic Change in Alveolar Bone after Nerve Injury

PloS one, 2017-01, Vol.12 (1), p.e0169201-e0169201

2017

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Arterial pressure lability is improved by sodium-glucose cotransporter 2 inhibitor in streptozotocin-induced diabetic rats

Hypertension research, 2017-07, Vol.40 (7), p.646-651

2017

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Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

Nature communications, 2012-06, Vol.3 (1), p.883-883, Article 883

2012

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Food-Derived Collagen Peptides, Prolyl-Hydroxyproline (Pro-Hyp), and Hydroxyprolyl-Glycine (Hyp-Gly) Enhance Growth of Primary Cultured Mouse Skin Fibroblast Using Fetal Bovine Serum Free from Hydroxyprolyl Peptide

International journal of molecular sciences, 2019-12, Vol.21 (1), p.229

2019

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Brain-enriched guanylate kinase-associated protein, a component of the post-synaptic density protein complexes, contributes to learning and memory

Scientific reports, 2023-12, Vol.13 (1), p.22027-22027, Article 22027

2023

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The skin is an important bulwark of acquired immunity against intestinal helminths

The Journal of experimental medicine, 2013-11, Vol.210 (12), p.2583-2595

2013

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Functional role of CD44v‐xCT system in the development of spasmolytic polypeptide‐expressing metaplasia

Cancer science, 2013-10, Vol.104 (10), p.1323-1329

2013

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Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy

Neuron (Cambridge, Mass.), 2012-08, Vol.75 (3), p.437-450

2012

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Single-laboratory Validation Study and Surveillance Using an Improved Multiresidue Analytical Method for Veterinary Drugs in Livestock Products by LC-MS/MS

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 2023/02/25, Vol.64(1), pp.53-60

2023

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Effects of iguratimod on glucocorticoid-induced disorder of bone metabolism in vitro

Journal of bone and mineral metabolism, 2021-07, Vol.39 (4), p.639-648

2021

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Synthesis and Structure–Activity Relationships of Novel Zwitterionic Compounds as Peroxisome Proliferator Activated Receptor α/γ Dual Agonists with Improved Physicochemical Properties

Discovery of N-[(1 R,2 S,5 S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4- c]pyridine-2-carboxamide hydrochloride: A novel, potent and orally active direct inhibitor of factor Xa

Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors

Suppressive Effect of β-Endorphin on Body Shaking Response to Ice Water Immersion and Synergistic Action of Vasoactive Intestinal Peptide on β-Endorphin in Anesthetized Rats

Hypermotility induced by vasoactive intestinal peptide in the rat: Its reciprocal action to cholecystokinin octapeptide

Behavioral effects of thyrotropin releasing hormone in frontal decorticated rats

Interaction of cholecystokinin with vasoactive intestinal peptide in body shaking response to ice-water immersion in rats

Potentiation of beta-endorphin effects by cholecystokinin antiserum in rats

Social isolation-induced aggression potentiates anxiety and depressive-like behavior in male mice subjected to unpredictable chronic mild stress

Heterozygous Disruption of Autism susceptibility candidate 2 Causes Impaired Emotional Control and Cognitive Memory

Loss of SMAD4 Promotes Lung Metastasis of Colorectal Cancer by Accumulation of CCR1+ Tumor-Associated Neutrophils through CCL15-CCR1 Axis

Altered dendritic morphology of Purkinje cells in Dyt1 ΔGAG knock-in and purkinje cell-specific Dyt1 conditional knockout mice

Arachidonic acid drives postnatal neurogenesis and elicits a beneficial effect on prepulse inhibition, a biological trait of psychiatric illnesses

Brg1 is required to maintain colorectal cancer stem cells

Lineage tracing and targeting of IL17RB⁺ tuft cell-like human colorectal cancer stem cells

Locally Produced BDNF Promotes Sclerotic Change in Alveolar Bone after Nerve Injury

Arterial pressure lability is improved by sodium-glucose cotransporter 2 inhibitor in streptozotocin-induced diabetic rats

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

Food-Derived Collagen Peptides, Prolyl-Hydroxyproline (Pro-Hyp), and Hydroxyprolyl-Glycine (Hyp-Gly) Enhance Growth of Primary Cultured Mouse Skin Fibroblast Using Fetal Bovine Serum Free from Hydroxyprolyl Peptide

Brain-enriched guanylate kinase-associated protein, a component of the post-synaptic density protein complexes, contributes to learning and memory

The skin is an important bulwark of acquired immunity against intestinal helminths

Functional role of CD44v‐xCT system in the development of spasmolytic polypeptide‐expressing metaplasia

Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy

Single-laboratory Validation Study and Surveillance Using an Improved Multiresidue Analytical Method for Veterinary Drugs in Livestock Products by LC-MS/MS

Effects of iguratimod on glucocorticoid-induced disorder of bone metabolism in vitro

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