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Targeting MET in cancer: rationale and progress

Nature reviews. Cancer, 2012-02, Vol.12 (2), p.89

2012

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Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

Nature communications, 2020-02, Vol.11 (1), p.929-929, Article 929

2020

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Tracing tumorigenesis in a solid tumor model at single-cell resolution

Nature communications, 2020-02, Vol.11 (1), p.991-12, Article 991

2020

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The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness

Nature communications, 2020-12, Vol.11 (1), p.6422-15, Article 6422

2020

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Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors

Cancer research (Chicago, Ill.), 2017-04, Vol.77 (8), p.2134-2147

2017

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SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling

Frontiers in immunology, 2019-10, Vol.10, p.2468-2468

2019

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MLL1 is required for maintenance of intestinal stem cells

PLoS genetics, 2021-12, Vol.17 (12), p.e1009250

2021

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Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo

Cell reports (Cambridge), 2018-04, Vol.23 (1), p.39-49

2018

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Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells

Nature communications, 2019-03, Vol.10 (1), p.1444-14, Article 1444

2019

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Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (9), p.3472-3477

2014

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Distinct roles of Wnt/β-catenin and Bmp signaling during early cardiogenesis

Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (47), p.18531-18536

2007

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The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis

Nature communications, 2018-08, Vol.9 (1), p.3259-17, Article 3259

2018

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Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors

PloS one, 2024-03, Vol.19 (3), p.e0282938-e0282938

2024

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Wnt signalling and its impact on development and cancer

Nature reviews. Cancer, 2008-05, Vol.8 (5), p.387-398

2008

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Continuous Tooth Generation in Mouse Is Induced by Activated Epithelial Wnt/β-Catenin Signaling

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (49), p.18627-18632

2006

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Orchestrating Wnt signalling for metabolic liver zonation

Nature cell biology, 2016-05, Vol.18 (5), p.463

Birchmeier, Walter

2016

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Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice

PloS one, 2021-06, Vol.16 (6), p.e0252649-e0252649

2021

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Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (27), p.10921-10926

2012

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Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (45), p.18174-18179

2013

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Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors

Breast cancer research : BCR, 2022-04, Vol.24 (1), p.23-23, Article 23

2022

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Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (20), p.7275-7280

2008

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Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence

Nature communications, 2023-08, Vol.14 (1), p.5106-5106, Article 5106

2023

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Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors

Molecular and Cellular Biology, 2002-02, Vol.22 (4), p.1184-1193

2002

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The role of Axin2 in calvarial morphogenesis and craniosynostosis

Development (Cambridge), 2005-04, Vol.132 (8), p.1995-2005

2005

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tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (39), p.16704-16709

2009

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Targeting MET in cancer: rationale and progress

Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

Tracing tumorigenesis in a solid tumor model at single-cell resolution

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness

Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors

SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling

MLL1 is required for maintenance of intestinal stem cells

Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo

Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine

Distinct roles of Wnt/β-catenin and Bmp signaling during early cardiogenesis

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis

Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors

Wnt signalling and its impact on development and cancer

Continuous Tooth Generation in Mouse Is Induced by Activated Epithelial Wnt/β-Catenin Signaling

Orchestrating Wnt signalling for metabolic liver zonation

Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice

Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development

Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors

Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking

Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence

Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors

The role of Axin2 in calvarial morphogenesis and craniosynostosis

tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development

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