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Isocitrate dehydrogenase mutations in gliomas

Neuro-oncology (Charlottesville, Va.), 2016-01, Vol.18 (1), p.16-26

2016

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The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma

Nature communications, 2018-05, Vol.9 (1), p.2087-11, Article 2087

2018

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The integrated genomic and epigenomic landscape of brainstem glioma

Nature communications, 2020-06, Vol.11 (1), p.3077-3077, Article 3077

2020

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Biological Role and Therapeutic Potential of IDH Mutations in Cancer

Cancer cell, 2018-08, Vol.34 (2), p.186-195

2018

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Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation

Cancer research (Chicago, Ill.), 2017-11, Vol.77 (22), p.6097-6108

2017

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CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP

Molecular cancer research, 2019-10, Vol.17 (10), p.2042-2050

2019

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Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas

Nature communications, 2024-01, Vol.15 (1), p.730-730, Article 730

2024

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Signal Integration and Gene Induction by a Functionally Distinct STAT3 Phosphoform

Molecular and cellular biology, 2014-05, Vol.34 (10), p.1800-1811

2014

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TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist

Acta neuropathologica communications, 2021-11, Vol.9 (1), p.178-178, Article 178

2021

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Targeting Isocitrate Dehydrogenase Mutations in Cancer: Emerging Evidence and Diverging Strategies

Clinical cancer research, 2021-01, Vol.27 (2), p.383-388

2021

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Mining cancer genomes for change-of-metabolic-function mutations

Communications biology, 2023-11, Vol.6 (1), p.1143-1143, Article 1143

2023

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STAT3-mediated Coincidence Detection Regulates Noncanonical Immediate Early Gene Induction

The Journal of biological chemistry, 2013-04, Vol.288 (17), p.11988-12003

2013

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Mechanisms of telomere maintenance and associated therapeutic vulnerabilities in malignant gliomas

Neuro-oncology (Charlottesville, Va.), 2024-01

2024

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Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma

The Journal of clinical investigation, 2024-01, Vol.134 (2)

2024

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Pooled genetic screens to identify vulnerabilities in TERT-promoter-mutant glioblastoma

Oncogene, 2023-10, Vol.42 (44), p.3274-3286

2023

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Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells

Neuro-oncology (Charlottesville, Va.), 2023-09, Vol.25 (9), p.1563-1575

2023

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Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib

Molecular cancer research, 2020-07, Vol.18 (7), p.968-980

2020

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Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe

Nanotechnology, 2019-07, Vol.30 (27), p.275101-275101

2019

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Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas

Neuro-oncology (Charlottesville, Va.), 2019-03, Vol.21 (4), p.440-450

2019

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Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression

Molecular cancer research, 2017-05, Vol.15 (5), p.507-520

2017

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Mitogen-activated protein kinase phosphatase-1 promotes neovascularization and angiogenic gene expression

Arteriosclerosis, thrombosis, and vascular biology, 2014-05, Vol.34 (5), p.1020

2014

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Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma

The Journal of clinical investigation, 2024-01, Vol.134 (2), p.1-8

2024

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Abstract 5821: The role of SMARCAL1 loss-of-function mutations in glioblastoma telomere maintenance

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5821-5821

2020

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Abstract 3143: A bioinformatic pipeline for identifying change-of-metabolic-function cancer mutations

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.3143-3143

2023

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Isocitrate dehydrogenase mutations in gliomas

The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma

The integrated genomic and epigenomic landscape of brainstem glioma

Biological Role and Therapeutic Potential of IDH Mutations in Cancer

Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation

CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP

Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas

Signal Integration and Gene Induction by a Functionally Distinct STAT3 Phosphoform

TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist

Targeting Isocitrate Dehydrogenase Mutations in Cancer: Emerging Evidence and Diverging Strategies

Mining cancer genomes for change-of-metabolic-function mutations

STAT3-mediated Coincidence Detection Regulates Noncanonical Immediate Early Gene Induction

Mechanisms of telomere maintenance and associated therapeutic vulnerabilities in malignant gliomas

Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition

Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma

Pooled genetic screens to identify vulnerabilities in TERT-promoter-mutant glioblastoma

Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells

Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib

Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe

Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas

Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression

Mitogen-activated protein kinase phosphatase-1 promotes neovascularization and angiogenic gene expression

Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma

Abstract 5821: The role of SMARCAL1 loss-of-function mutations in glioblastoma telomere maintenance

Abstract 3143: A bioinformatic pipeline for identifying change-of-metabolic-function cancer mutations

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