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Assemblages: functional units formed by cellular phase separation

The Journal of cell biology, 2014-09, Vol.206 (5), p.579-588

2014

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EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

Nature (London), 2018-03, Vol.555 (7696), p.387

2018

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EWS-FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex

Nucleic acids research, 2019-10, Vol.47 (18), p.9619

2019

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YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion

PloS one, 2011-04, Vol.6 (4), p.e19343-e19343

2011

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Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cells

PloS one, 2021-06, Vol.16 (6), p.e0253170

2021

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O‑Linked‑N‑Acetylglucosaminylation of the RNA-Binding Protein EWS N‑Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics

Journal of the American Chemical Society, 2021-08, Vol.143 (30), p.11520-11534

2021

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High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition

PloS one, 2010-11, Vol.5 (11), p.e13943

2010

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Oncogenic partnerships: EWS-FLI1 protein interactions initiate key pathways of Ewing's sarcoma

Clinical cancer research, 2010-08, Vol.16 (16), p.4077-4083

2010

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Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

The Journal of clinical investigation, 2011-01, Vol.121 (1), p.148-160

2011

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Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (11), p.E1307-E1316

2015

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Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma

Science signaling, 2014-05, Vol.7 (324), p.ra42

2014

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A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model

PloS one, 2014-12, Vol.9 (12), p.e114260-e114260

2014

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Mutational Inactivation of STAG2 Causes Aneuploidy in Human Cancer

Science (American Association for the Advancement of Science), 2011-08, Vol.333 (6045), p.1039-1043

2011

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USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity

Molecular cancer, 2023-12, Vol.22 (1), p.204-204, Article 204

2023

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Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives

Journal of clinical medicine, 2021-04, Vol.10 (8), p.1685

2021

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Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors

Science (American Association for the Advancement of Science), 2018-08, Vol.361 (6405)

2018

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A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

Nature medicine, 2009-07, Vol.15 (7), p.750-756

2009

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The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents

Clinical cancer research, 2019-08, Vol.25 (16), p.5167-5176

2019

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Osteosarcoma enters a post genomic era with in silico opportunities: Generation of the High Dimensional Database for facilitating sarcoma biology research: A report from the Children's Oncology Group and the QuadW Foundation

PloS one, 2017-07, Vol.12 (7), p.e0181204-e0181204

2017

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An intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregation

PloS one, 2012-11, Vol.7 (11), p.e48243-e48243

2012

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Combining PARP-1 inhibition and radiation in Ewing sarcoma results in lethal DNA damage

Molecular cancer therapeutics, 2013-11, Vol.12 (11), p.2591-2600

2013

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Ezrin Inhibition Up-regulates Stress Response Gene Expression

The Journal of biological chemistry, 2016-06, Vol.291 (25), p.13257-13270

2016

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Beta-catenin accelerates human papilloma virus type-16 mediated cervical carcinogenesis in transgenic mice

PloS one, 2011-11, Vol.6 (11), p.e27243

2011

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Synovial sarcoma is a gateway to the role of chromatin remodeling in cancer

Cancer and metastasis reviews, 2015-09, Vol.34 (3), p.417-428

2015

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The Role of IGF‐1R in Pediatric Malignancies

The oncologist (Dayton, Ohio), 2009-01, Vol.14 (1), p.83-91

2009

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Assemblages: functional units formed by cellular phase separation

EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

EWS-FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex

YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion

Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cells

O‑Linked‑N‑Acetylglucosaminylation of the RNA-Binding Protein EWS N‑Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics

High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition

Oncogenic partnerships: EWS-FLI1 protein interactions initiate key pathways of Ewing's sarcoma

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing

Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma

A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model

Mutational Inactivation of STAG2 Causes Aneuploidy in Human Cancer

USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity

Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives

Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents

Osteosarcoma enters a post genomic era with in silico opportunities: Generation of the High Dimensional Database for facilitating sarcoma biology research: A report from the Children's Oncology Group and the QuadW Foundation

An intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregation

Combining PARP-1 inhibition and radiation in Ewing sarcoma results in lethal DNA damage

Ezrin Inhibition Up-regulates Stress Response Gene Expression

Beta-catenin accelerates human papilloma virus type-16 mediated cervical carcinogenesis in transgenic mice

Synovial sarcoma is a gateway to the role of chromatin remodeling in cancer

The Role of IGF‐1R in Pediatric Malignancies

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