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A Method to Prepare Claudin-Modulating Recombinant Proteins

Methods in molecular biology (Clifton, N.J.), 2020, Vol.2109, p.251

2020

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Tight junction modulators for drug delivery to the central nervous system

Drug discovery today, 2020-08, Vol.25 (8), p.1477-1486

2020

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Design and In Vitro Evaluation of Splice-Switching Oligonucleotides Bearing Locked Nucleic Acids, Amido-Bridged Nucleic Acids, and Guanidine-Bridged Nucleic Acids

International journal of molecular sciences, 2021-03, Vol.22 (7), p.3526

2021

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The Clinical Innovation Network: a policy for promoting development of drugs and medical devices in Japan

Drug discovery today, 2019-01, Vol.24 (1), p.4-8

2019

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Association of Plasma Claudin-5 with Age and Alzheimer Disease

International journal of molecular sciences, 2024-02, Vol.25 (3), p.1419

2024

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Safety and efficacy of an anti-claudin-5 monoclonal antibody to increase blood–brain barrier permeability for drug delivery to the brain in a non-human primate

Journal of controlled release, 2021-08, Vol.336, p.105-111

2021

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Claudin-5: A Pharmacological Target to Modify the Permeability of the Blood–Brain Barrier

Biological and Pharmaceutical Bulletin, 2021/10/01, Vol.44(10), pp.1380-1390

2021

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Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening

PloS one, 2018-05, Vol.13 (5), p.e0197373-e0197373

2018

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The Roadmap to Approval under Japan’s Two-Track Regulatory System: Comparing Six Regenerative Medical Products

Cell stem cell, 2020-10, Vol.27 (4), p.515-518

2020

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A Review of the Regulatory Framework for Initiation and Acceleration of Patient Access to Innovative Medical Products in Japan

Clinical pharmacology and therapeutics, 2019-09, Vol.106 (3), p.508-511

2019

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New Japanese Regulatory Frameworks for Post-Marketing Management of Pharmaceutical Products

Pharmaceutical research, 2020-07, Vol.37 (7), p.122, Article 122

2020

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Potential for Tight Junction Protein-Directed Drug Development Using Claudin Binders and Angubindin-1

International journal of molecular sciences, 2019-08, Vol.20 (16), p.4016

2019

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The Role of PPARs in Cancer

PPAR Research, 2008-01, Vol.2008, p.102737-15

2008

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Radiolabeled cCPE Peptides for SPECT Imaging of Claudin-4 Overexpression in Pancreatic Cancer

Journal of Nuclear Medicine, 2020-12, Vol.61 (12), p.1756-1763

2020

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Enhancement of exon skipping activity by reduction in the secondary structure content of LNA-based splice-switching oligonucleotides

Chemical communications (Cambridge, England), 2019-06, Vol.55 (48), p.685-6853

2019

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A Concept for a Japanese Regulatory Framework for Emerging Medical Devices with Frequently Modified Behavior

Clinical and translational science, 2020-09, Vol.13 (5), p.877-879

2020

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Overview of the Premarketing and Postmarketing Requirements for Drugs Granted Japanese Conditional Marketing Approval

Clinical and translational science, 2021-05, Vol.14 (3), p.806-811

2021

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Tight Junction Modulating Bioprobes for Drug Delivery System to the Brain: A Review

Pharmaceutics, 2020-12, Vol.12 (12), p.1236

2020

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Structural development of 1H-pyrazolo-[3,4-b]pyridine-4-carboxylic acid derivatives as human peroxisome proliferator-activated receptor alpha (PPARα)-selective agonists

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2124-2128

2019

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Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase Activity

PloS one, 2016-10, Vol.11 (10), p.e0165766-e0165766

2016

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Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

Proceedings of the National Academy of Sciences - PNAS, 2003-12, Vol.100 (26), p.15924-15929

2003

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Structural Basis for PPARα Activation by 1H-pyrazolo-[3,4-b]pyridine Derivatives

Scientific reports, 2020-05, Vol.10 (1), p.7623-7623, Article 7623

2020

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Facilitation of adipocyte differentiation of 3T3-L1 cells by debrominated tetrabromobisphenol A compounds detected in Japanese breast milk

Environmental research, 2015-07, Vol.140, p.157-164

2015

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Analysis of the subcellular localization of the human histone methyltransferase SETDB1

Biochemical and biophysical research communications, 2015-10, Vol.465 (4), p.725-731

2015

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Drug discovery and development scheme for liver-targeting bridged nucleic acid antisense oligonucleotides

Molecular therapy. Nucleic acids, 2021-12, Vol.26, p.957-969

2021

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A Method to Prepare Claudin-Modulating Recombinant Proteins

Tight junction modulators for drug delivery to the central nervous system

Design and In Vitro Evaluation of Splice-Switching Oligonucleotides Bearing Locked Nucleic Acids, Amido-Bridged Nucleic Acids, and Guanidine-Bridged Nucleic Acids

The Clinical Innovation Network: a policy for promoting development of drugs and medical devices in Japan

Association of Plasma Claudin-5 with Age and Alzheimer Disease

Safety and efficacy of an anti-claudin-5 monoclonal antibody to increase blood–brain barrier permeability for drug delivery to the brain in a non-human primate

Claudin-5: A Pharmacological Target to Modify the Permeability of the Blood–Brain Barrier

Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening

The Roadmap to Approval under Japan’s Two-Track Regulatory System: Comparing Six Regenerative Medical Products

A Review of the Regulatory Framework for Initiation and Acceleration of Patient Access to Innovative Medical Products in Japan

New Japanese Regulatory Frameworks for Post-Marketing Management of Pharmaceutical Products

Potential for Tight Junction Protein-Directed Drug Development Using Claudin Binders and Angubindin-1

The Role of PPARs in Cancer

Radiolabeled cCPE Peptides for SPECT Imaging of Claudin-4 Overexpression in Pancreatic Cancer

Enhancement of exon skipping activity by reduction in the secondary structure content of LNA-based splice-switching oligonucleotides

A Concept for a Japanese Regulatory Framework for Emerging Medical Devices with Frequently Modified Behavior

Overview of the Premarketing and Postmarketing Requirements for Drugs Granted Japanese Conditional Marketing Approval

Tight Junction Modulating Bioprobes for Drug Delivery System to the Brain: A Review

Structural development of 1H-pyrazolo-[3,4-b]pyridine-4-carboxylic acid derivatives as human peroxisome proliferator-activated receptor alpha (PPARα)-selective agonists

Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase Activity

Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

Structural Basis for PPARα Activation by 1H-pyrazolo-[3,4-b]pyridine Derivatives

Facilitation of adipocyte differentiation of 3T3-L1 cells by debrominated tetrabromobisphenol A compounds detected in Japanese breast milk

Analysis of the subcellular localization of the human histone methyltransferase SETDB1

Drug discovery and development scheme for liver-targeting bridged nucleic acid antisense oligonucleotides

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