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Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells

Developmental cell, 2015-09, Vol.34 (6), p.656-668

2015

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Evidence for Loss in Identity, De-Differentiation, and Trans -Differentiation of Islet β-Cells in Type 2 Diabetes

Frontiers in genetics, 2017-03, Vol.8, p.35-35

2017

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Gestational Diabetes Mellitus From Inactivation of Prolactin Receptor and MafB in Islet β-Cells

Diabetes (New York, N.Y.), 2016-08, Vol.65 (8), p.2331-2341

2016

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Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health

Diabetes (New York, N.Y.), 2020-03, Vol.69 (3), p.342-354

2020

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Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks

The Journal of clinical investigation, 2019-01, Vol.129 (1), p.246-251

2019

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α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes

Cell reports (Cambridge), 2018-03, Vol.22 (10), p.2667-2676

2018

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Dynamic Recruitment of Functionally Distinct Swi/Snf Chromatin Remodeling Complexes Modulates Pdx1 Activity in Islet β Cells

Cell reports (Cambridge), 2015-03, Vol.10 (12), p.2032-2042

2015

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Repression of latent NF-κB enhancers by PDX1 regulates β cell functional heterogeneity

Cell metabolism, 2024-01, Vol.36 (1), p.90-102.e7

2024

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Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue

Diabetologia, 2019-06, Vol.62 (6), p.1036-1047

2019

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Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state

Cell metabolism, 2022-02, Vol.34 (2), p.256-268.e5

2022

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Stress-impaired transcription factor expression and insulin secretion in transplanted human islets

The Journal of clinical investigation, 2016-05, Vol.126 (5), p.1857-1870

2016

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Cognate Nonlytic Interactions between CD8 + T Cells and Breast Cancer Cells Induce Cancer Stem Cell-like Properties

Cancer research (Chicago, Ill.), 2019-04, Vol.79 (7), p.1507-1519

2019

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Anti-CD39 and anti-CD73 antibodies A1 and 7G2 improve targeted therapy in ovarian cancer by blocking adenosine-dependent immune evasion

American journal of translational research, 2014-01, Vol.6 (2), p.129-139

2014

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Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages - a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape

Journal for immunotherapy of cancer, 2016-08, Vol.4 (1), p.49-49, Article 49

2016

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Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes

Diabetes (New York, N.Y.), 2021-11, Vol.70 (11), p.2595-2607

2021

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Oxidative Stress-mediated, Post-translational Loss of MafA Protein as a Contributing Mechanism to Loss of Insulin Gene Expression in Glucotoxic Beta Cells

The Journal of biological chemistry, 2005-03, Vol.280 (12), p.11107-11113

2005

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Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas

Diabetes (New York, N.Y.), 2009-09, Vol.58 (9), p.2059-2069

2009

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In vivo studies of glucagon secretion by human islets transplanted in mice

Nature metabolism, 2020-06, Vol.2 (6), p.547

2020

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Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation

Genes & development, 2006-01, Vol.20 (2), p.253-266

2006

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Members of the Large Maf Transcription Family Regulate Insulin Gene Transcription in Islet β Cells

Molecular and Cellular Biology, 2003-09, Vol.23 (17), p.6049-6062

2003

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Disruption of a Novel Krüppel-like Transcription Factor p300-regulated Pathway for Insulin Biosynthesis Revealed by Studies of the c.-331 INS Mutation Found in Neonatal Diabetes Mellitus

The Journal of biological chemistry, 2011-08, Vol.286 (32), p.28414-28424

2011

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MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes

Cell reports (Cambridge), 2016-03, Vol.14 (8), p.1991-2002

2016

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Ptf1a Binds to and Activates Area III, a Highly Conserved Region of the Pdx1 Promoter That Mediates Early Pancreas-Wide Pdx1 Expression

Molecular and Cellular Biology, 2007-06, Vol.27 (11), p.4093-4104

2007

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Phosphorylation within the MafA N Terminus Regulates C-terminal Dimerization and DNA Binding

The Journal of biological chemistry, 2010-04, Vol.285 (17), p.12655-12661

2010

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Combinatorial transcription factor profiles predict mature and functional human islet α and β cells

JCI insight, 2021-09, Vol.6 (18)

2021

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Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells

Evidence for Loss in Identity, De-Differentiation, and Trans -Differentiation of Islet β-Cells in Type 2 Diabetes

Gestational Diabetes Mellitus From Inactivation of Prolactin Receptor and MafB in Islet β-Cells

Lipid Droplet Accumulation in Human Pancreatic Islets Is Dependent On Both Donor Age and Health

Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks

α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes

Dynamic Recruitment of Functionally Distinct Swi/Snf Chromatin Remodeling Complexes Modulates Pdx1 Activity in Islet β Cells

Repression of latent NF-κB enhancers by PDX1 regulates β cell functional heterogeneity

Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue

Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state

Stress-impaired transcription factor expression and insulin secretion in transplanted human islets

Cognate Nonlytic Interactions between CD8 + T Cells and Breast Cancer Cells Induce Cancer Stem Cell-like Properties

Anti-CD39 and anti-CD73 antibodies A1 and 7G2 improve targeted therapy in ovarian cancer by blocking adenosine-dependent immune evasion

Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages - a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape

Lipid Droplets Protect Human β-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes

Oxidative Stress-mediated, Post-translational Loss of MafA Protein as a Contributing Mechanism to Loss of Insulin Gene Expression in Glucotoxic Beta Cells

Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas

In vivo studies of glucagon secretion by human islets transplanted in mice

Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation

Members of the Large Maf Transcription Family Regulate Insulin Gene Transcription in Islet β Cells

Disruption of a Novel Krüppel-like Transcription Factor p300-regulated Pathway for Insulin Biosynthesis Revealed by Studies of the c.-331 INS Mutation Found in Neonatal Diabetes Mellitus

MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes

Ptf1a Binds to and Activates Area III, a Highly Conserved Region of the Pdx1 Promoter That Mediates Early Pancreas-Wide Pdx1 Expression

Phosphorylation within the MafA N Terminus Regulates C-terminal Dimerization and DNA Binding

Combinatorial transcription factor profiles predict mature and functional human islet α and β cells

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