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Modification of ghrelin receptor signaling by somatostatin receptor-5 regulates insulin release

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (46), p.19003-19008

2012

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Des-Acyl Ghrelin Induces Food Intake by a Mechanism Independent of the Growth Hormone Secretagogue Receptor

Endocrinology (Philadelphia), 2006-05, Vol.147 (5), p.2306-2314

2006

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The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

Neuron (Cambridge, Mass.), 2003-02, Vol.37 (4), p.649-661

2003

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Ghrelin Prevents Cisplatin-Induced Mechanical Hyperalgesia and Cachexia

Endocrinology (Philadelphia), 2008-02, Vol.149 (2), p.455-460

2008

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An Essential Component in Steroid Synthesis, the Steroidogenic Acute Regulatory Protein, Is Expressed in Discrete Regions of the Brain

The Journal of neuroscience, 2002-12, Vol.22 (24), p.10613-10620

2002

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Dissociating ghrelin-dependent G protein from β-arrestin-2 signaling in transgenic rats

Science signaling, 2016-04, Vol.9 (424), p.fs6

Smith, Roy G

2016

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Molecular Analysis of Rat Pituitary and Hypothalamic Growth Hormone Secretagogue Receptors

Molecular endocrinology (Baltimore, Md.), 1997-04, Vol.11 (4), p.415-423

1997

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Molecular cloning and characterization of a new receptor for galanin

FEBS letters, 1997-04, Vol.405 (3), p.285-290

1997

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Blockade of growth hormone secretagogue receptor 1A signaling by JMV 2959 attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition

Psychopharmacologia, 2015-12, Vol.232 (23), p.4285-4292

2015

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A Nonpeptidyl Growth Hormone Secretagogue

Science (American Association for the Advancement of Science), 1993-06, Vol.260 (5114), p.1640-1643

1993

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Structural Requirements for the Activation of the Human Growth Hormone Secretagogue Receptor by Peptide and Nonpeptide Secretagogues

Molecular endocrinology (Baltimore, Md.), 1998-01, Vol.12 (1), p.137-145

1998

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Initial structure–activity relationship of a novel class of nonpeptidyl GnRH receptor antagonists: 2-arylindoles

Bioorganic & medicinal chemistry letters, 2001-02, Vol.11 (4), p.509-513

2001

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1-[2(R)-(2-Amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]-3- benzylpiperidine-3(S)-carboxylic Acid Ethyl Ester (L-163,540): A Potent, Orally Bioavailable, and Short-Duration Growth Hormone Secretagogue

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2439-2441

1998

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Antidiabetic Activity of a Highly Potent and Selective Nonpeptide Somatostatin Receptor Subtype-2 Agonist

Endocrinology (Philadelphia), 2006-10, Vol.147 (10), p.4664-4673

2006

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Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues

Brain research. Molecular brain research., 1997-08, Vol.48 (1), p.23-29

1997

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Synthesis and Biological Activities of Potent Peptidomimetics Selective for Somatostatin Receptor Subtype 2

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (18), p.10836-10841

1998

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Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin‐specific receptor

British journal of pharmacology, 2003-06, Vol.139 (3), p.575-584

2003

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Down-regulation of the Expression of the Obese Gene by an Antidiabetic Thiazolidinedione in Zucker Diabetic Fatty Rats and db/db Mice (∗)

The Journal of biological chemistry, 1996-04, Vol.271 (16), p.9455-9459

1996

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The aging process: where are the drug opportunities?

Current Opinion in Chemical Biology, 2000-08, Vol.4 (4), p.371-376

Smith, Roy G

2000

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Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist

Bioorganic & medicinal chemistry letters, 1999-09, Vol.9 (17), p.2615-2620

1999

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Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists

Bioorganic & medicinal chemistry letters, 1999-09, Vol.9 (17), p.2621-2624

1999

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Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides

Bioorganic & medicinal chemistry letters, 2000-03, Vol.10 (5), p.443-447

2000

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SAR studies of novel 5-substituted 2-arylindoles as nonpeptidyl GnRH receptor antagonists

Bioorganic & medicinal chemistry letters, 2001-02, Vol.11 (4), p.515-517

2001

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A Novel 3-Substituted Benzazepinone Growth Hormone Secretagogue (L-692,429)

Journal of medicinal chemistry, 1994-04, Vol.37 (7), p.897-906

1994

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2-(3,5-Dimethylphenyl)tryptamine Derivatives that Bind to the GnRH Receptor

Bioorganic & medicinal chemistry letters, 2001-04, Vol.11 (8), p.1073-1076

2001

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Modification of ghrelin receptor signaling by somatostatin receptor-5 regulates insulin release

Des-Acyl Ghrelin Induces Food Intake by a Mechanism Independent of the Growth Hormone Secretagogue Receptor

The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

Ghrelin Prevents Cisplatin-Induced Mechanical Hyperalgesia and Cachexia

An Essential Component in Steroid Synthesis, the Steroidogenic Acute Regulatory Protein, Is Expressed in Discrete Regions of the Brain

Dissociating ghrelin-dependent G protein from β-arrestin-2 signaling in transgenic rats

Molecular Analysis of Rat Pituitary and Hypothalamic Growth Hormone Secretagogue Receptors

Molecular cloning and characterization of a new receptor for galanin

Blockade of growth hormone secretagogue receptor 1A signaling by JMV 2959 attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition

A Nonpeptidyl Growth Hormone Secretagogue

Structural Requirements for the Activation of the Human Growth Hormone Secretagogue Receptor by Peptide and Nonpeptide Secretagogues

Initial structure–activity relationship of a novel class of nonpeptidyl GnRH receptor antagonists: 2-arylindoles

1-[2(R)-(2-Amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]-3- benzylpiperidine-3(S)-carboxylic Acid Ethyl Ester (L-163,540): A Potent, Orally Bioavailable, and Short-Duration Growth Hormone Secretagogue

Antidiabetic Activity of a Highly Potent and Selective Nonpeptide Somatostatin Receptor Subtype-2 Agonist

Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues

Synthesis and Biological Activities of Potent Peptidomimetics Selective for Somatostatin Receptor Subtype 2

Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin‐specific receptor

Down-regulation of the Expression of the Obese Gene by an Antidiabetic Thiazolidinedione in Zucker Diabetic Fatty Rats and db/db Mice (∗)

The aging process: where are the drug opportunities?

Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist

Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists

Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides

SAR studies of novel 5-substituted 2-arylindoles as nonpeptidyl GnRH receptor antagonists

A Novel 3-Substituted Benzazepinone Growth Hormone Secretagogue (L-692,429)

2-(3,5-Dimethylphenyl)tryptamine Derivatives that Bind to the GnRH Receptor

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