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Exploration of Bacterial Bottlenecks and Streptococcus pneumoniae Pathogenesis by CRISPRi-Seq

Cell host & microbe, 2021-01, Vol.29 (1), p.107-120.e6

2021

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Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages

Immunity (Cambridge, Mass.), 2017-03, Vol.46 (3), p.457-473

2017

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Toll‐like receptor 4 signaling in hematopoietic‐lineage cells contributes to the enhanced activity of the human vaccine adjuvant AS01

European journal of immunology, 2019-12, Vol.49 (12), p.2134-2145

2019

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Activation of Type 3 Innate Lymphoid Cells and Interleukin 22 Secretion in the Lungs During Streptococcus pneumoniae Infection

The Journal of infectious diseases, 2014-08, Vol.210 (3), p.493-503

2014

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The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea

PLoS pathogens, 2010-09, Vol.6 (9), p.e1001097-e1001097

2010

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Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection

PLoS pathogens, 2018-10, Vol.14 (10), p.e1007360-e1007360

2018

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Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response

Mucosal immunology, 2020-01, Vol.13 (1), p.128-139

2020

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Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence

PLoS biology, 2023-01, Vol.21 (1), p.e3001990-e3001990

2023

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Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq

eLife, 2022-06, Vol.11

2022

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Flagellin Promotes Myeloid Differentiation Factor 88-Dependent Development of Th2-Type Response

The Journal of immunology (1950), 2004-06, Vol.172 (11), p.6922-6930

2004

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Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract

Vaccine, 2015-06, Vol.33 (29), p.3331-3341

2015

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A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against S. pneumoniae in Mice

Pharmaceutics, 2021-03, Vol.13 (4), p.469-12

2021

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NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium

PloS one, 2013-10, Vol.8 (10), p.e77204-e77204

2013

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Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae

Frontiers in immunology, 2018-10, Vol.9, p.2175-2175

2018

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Nod-like receptors: cytosolic watchdogs for immunity against pathogens

PLoS pathogens, 2007-12, Vol.3 (12), p.e152-e152

2007

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Inheritance of the Lysozyme Inhibitor Ivy Was an Important Evolutionary Step by Yersinia pestis to Avoid the Host Innate Immune Response

The Journal of infectious diseases, 2013-05, Vol.207 (10), p.1535-1543

2013

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Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner

PloS one, 2016-11, Vol.11 (11), p.e0163694

2016

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IL‐22 is produced by γC‐independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS‐induced lethality

European journal of immunology, 2011-04, Vol.41 (4), p.1075-1085

2011

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The GM-CSF Released by Airway Epithelial Cells Orchestrates the Mucosal Adjuvant Activity of Flagellin

The Journal of immunology (1950), 2020-11, Vol.205 (10), p.2873-2882

2020

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Early Protection against Pertussis Induced by Live Attenuated Bordetella pertussis BPZE1 Depends on TLR4

The Journal of immunology (1950), 2019-12, Vol.203 (12), p.3293-3300

2019

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The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia

Pharmaceutics, 2021-04, Vol.13 (5), p.601

2021

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Role of Toll‐like receptors in costimulating cytotoxic T cell responses

European journal of immunology, 2003-06, Vol.33 (6), p.1465-1470

2003

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Synthetic gene-regulatory networks in the opportunistic human pathogen Streptococcus pneumoniae

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (44), p.27608-27619

2020

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Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells

Immunobiology (1979), 2015-10, Vol.220 (10), p.1161-1169

2015

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Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5), p.1541-1546

2015

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Exploration of Bacterial Bottlenecks and Streptococcus pneumoniae Pathogenesis by CRISPRi-Seq

Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages

Toll‐like receptor 4 signaling in hematopoietic‐lineage cells contributes to the enhanced activity of the human vaccine adjuvant AS01

Activation of Type 3 Innate Lymphoid Cells and Interleukin 22 Secretion in the Lungs During Streptococcus pneumoniae Infection

The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea

Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection

Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response

Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence

Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq

Flagellin Promotes Myeloid Differentiation Factor 88-Dependent Development of Th2-Type Response

Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract

A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against S. pneumoniae in Mice

NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium

Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae

Nod-like receptors: cytosolic watchdogs for immunity against pathogens

Inheritance of the Lysozyme Inhibitor Ivy Was an Important Evolutionary Step by Yersinia pestis to Avoid the Host Innate Immune Response

Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner

IL‐22 is produced by γC‐independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS‐induced lethality

The GM-CSF Released by Airway Epithelial Cells Orchestrates the Mucosal Adjuvant Activity of Flagellin

Early Protection against Pertussis Induced by Live Attenuated Bordetella pertussis BPZE1 Depends on TLR4

The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia

Role of Toll‐like receptors in costimulating cytotoxic T cell responses

Synthetic gene-regulatory networks in the opportunistic human pathogen Streptococcus pneumoniae

Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells

Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5

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