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The 2-oxoglutarate analog 3-oxoglutarate decreases normoxic hypoxia-inducible factor-1α in cancer cells, induces cell death, and reduces tumor xenograft growth

Hypoxia, 2016-01, Vol.4, p.15-27

2016

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4582 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) DEPLETION MUST BE SEVERE TO INDUCE CARDIAC DYSFUNCTION AND EVENTUAL FAILURE

Journal of clinical and translational science, 2020-06, Vol.4 (s1), p.13-13

2020

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5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination

Molecular genetics and metabolism, 2018-09, Vol.125 (1-2), p.118-126

2018

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Absence of Detectable Arsenate in DNA from Arsenate-Grown GFAJ-1 Cells

Science (American Association for the Advancement of Science), 2012-07, Vol.337 (6093), p.470-473

2012

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Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

Nature chemical biology, 2009-08, Vol.5 (8), p.593-599

2009

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Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach

Nature protocols, 2008-08, Vol.3 (8), p.1299-1311

2008

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Abstract 1013: Quantification of NADPH balance in cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1013-1013

2016

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Abstract 13461: Severe, but Not Mild Decreases in Nicotinamide Adenine Dinucleotide (NAD) Cause Heart Failure

Circulation (New York, N.Y.), 2019-11, Vol.140 (Suppl_1 Suppl 1), p.A13461-A13461

2019

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Abstract 21: The mTORC2 target Akt is regulated in response to glutamine metabolite levels

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.21-21

2016

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Abstract 232: Pharmacological and genetic dissection of one carbon pathway provides novel insights into generation, transformation and utilization of one carbon units

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.232-232

2016

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Abstract 285: Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.285-285

2023

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Abstract 2953: Rev-erbα modulates Myc-driven cancer cell growth and altered metabolism

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.2953-2953

2014

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Abstract 2992: Cellular pharmacodynamics of mitochondrial one-carbon metabolism-targeting 5-substituted pyrrolo[3,2- d ]pyrimidine antifolates

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2992-2992

2019

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Abstract 33: Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.33-33

2010

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Abstract 3980: Dual targeting mitochondrial and cytosolic one-carbon metabolism via the proton-coupled folate transporter with novel 5-substituted pyrrolo[3,2- d ]pyrimidine antifolates

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3980-3980

2018

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Abstract 4709: Compartmental flexibility in mammalian folate metabolism

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4709-4709

2015

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Abstract 562: Comprehensive Arteriovenous Metabolomics in the Human Heart

Circulation research, 2019-08, Vol.125 (Suppl_1)

2019

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Abstract 5713: Reprogramming of serine metabolism during breast cancer progression

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5713-5713

2020

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Abstract A14: Role of mitochondrial folate metabolism in cancer cell growth and proliferation

Molecular cancer research, 2016-01, Vol.14 (1_Supplement), p.A14-A14

2016

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Abstract B27: A phase Ib/II trial of high-dose (HD) ascorbic acid (AA) + paclitaxel protein bound (PP) + cisplatin (C) + gemcitabine (G) in patients (pts) with metastatic pancreatic cancer (MPC)

Cancer research (Chicago, Ill.), 2019-12, Vol.79 (24_Supplement), p.B27-B27

2019

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Abstract CT163: A Phase Ib/II trial of high dose ascorbic acid (AA) + paclitaxel protein bound (PP) + cisplatin (C) + gemcitabine (G) in patients (pts) with metastatic pancreatic cancer (MPC)

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.CT163-CT163

2019

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Abstract CT549: Randomized Phase II trial of two different nutritional approaches for patients receiving treatment for their advanced pancreatic cancer

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.CT549-CT549

2022

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Abstract IA018: ATP production in pancreas cancer and tumor infiltrating lymphocytes

Cancer research (Chicago, Ill.), 2022-11, Vol.82 (22_Supplement), p.IA018-IA018

Rabinowitz, Joshua D.

2022

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Abstract LB-61: Targeting cancer cell metabolism in pancreatic cancer: p53, a key regulator of glycolysis and a major factor deciding the outcome of targeting the Warburg effect

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.LB-61-LB-61

2012

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Abstract P3-02-06: Tracing glucose catabolism in human triple negative breast cancer tumors

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (4_Supplement), p.P3-P3-02-06

2020

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The 2-oxoglutarate analog 3-oxoglutarate decreases normoxic hypoxia-inducible factor-1α in cancer cells, induces cell death, and reduces tumor xenograft growth

4582 NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) DEPLETION MUST BE SEVERE TO INDUCE CARDIAC DYSFUNCTION AND EVENTUAL FAILURE

5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination

Absence of Detectable Arsenate in DNA from Arsenate-Grown GFAJ-1 Cells

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach

Abstract 1013: Quantification of NADPH balance in cancer

Abstract 13461: Severe, but Not Mild Decreases in Nicotinamide Adenine Dinucleotide (NAD) Cause Heart Failure

Abstract 21: The mTORC2 target Akt is regulated in response to glutamine metabolite levels

Abstract 232: Pharmacological and genetic dissection of one carbon pathway provides novel insights into generation, transformation and utilization of one carbon units

Abstract 285: Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma

Abstract 2953: Rev-erbα modulates Myc-driven cancer cell growth and altered metabolism

Abstract 2992: Cellular pharmacodynamics of mitochondrial one-carbon metabolism-targeting 5-substituted pyrrolo[3,2- d ]pyrimidine antifolates

Abstract 33: Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Abstract 3980: Dual targeting mitochondrial and cytosolic one-carbon metabolism via the proton-coupled folate transporter with novel 5-substituted pyrrolo[3,2- d ]pyrimidine antifolates

Abstract 4709: Compartmental flexibility in mammalian folate metabolism

Abstract 562: Comprehensive Arteriovenous Metabolomics in the Human Heart

Abstract 5713: Reprogramming of serine metabolism during breast cancer progression

Abstract A14: Role of mitochondrial folate metabolism in cancer cell growth and proliferation

Abstract B27: A phase Ib/II trial of high-dose (HD) ascorbic acid (AA) + paclitaxel protein bound (PP) + cisplatin (C) + gemcitabine (G) in patients (pts) with metastatic pancreatic cancer (MPC)

Abstract CT163: A Phase Ib/II trial of high dose ascorbic acid (AA) + paclitaxel protein bound (PP) + cisplatin (C) + gemcitabine (G) in patients (pts) with metastatic pancreatic cancer (MPC)

Abstract CT549: Randomized Phase II trial of two different nutritional approaches for patients receiving treatment for their advanced pancreatic cancer

Abstract IA018: ATP production in pancreas cancer and tumor infiltrating lymphocytes

Abstract LB-61: Targeting cancer cell metabolism in pancreatic cancer: p53, a key regulator of glycolysis and a major factor deciding the outcome of targeting the Warburg effect

Abstract P3-02-06: Tracing glucose catabolism in human triple negative breast cancer tumors

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