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Molecular Mechanisms of Insulin Resistance in Humans and Their Potential Links With Mitochondrial Dysfunction

Diabetes (New York, N.Y.), 2006-12, Vol.55 (Supplement 2), p.S9-S15

2006

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Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

Diabetes (New York, N.Y.), 2012-11, Vol.61 (11), p.2711-2717

2012

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Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients

Diabetes (New York, N.Y.), 2007-05, Vol.56 (5), p.1376-1381

2007

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Cellular Mechanism by Which Estradiol Protects Female Ovariectomized Mice From High-Fat Diet-Induced Hepatic and Muscle Insulin Resistance

Endocrinology (Philadelphia), 2013-03, Vol.154 (3), p.1021-1028

2013

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Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications: Potential Role of Alterations in Mitochondrial Function in the Pathogenesis of Insulin Resistance and Type 2 Diabetes

Endocrinology (Philadelphia), 2020-04, Vol.161 (4), p.1

2020

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Disassociation of Liver and Muscle Insulin Resistance from Ectopic Lipid Accumulation in Low-Birth-Weight Individuals

The journal of clinical endocrinology and metabolism, 2011-12, Vol.96 (12), p.3873-3880

2011

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Lipid-induced insulin resistance: unravelling the mechanism

The Lancet (British edition), 2010-06, Vol.375 (9733), p.2267-2277

2010

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Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (13), p.7347-7354

2020

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Disordered Lipid Metabolism and the Pathogenesis of Insulin Resistance

Physiological reviews, 2007-04, Vol.87 (2), p.507-520

2007

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Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation

Cell, 2018-01, Vol.172 (1-2), p.234-248.e17

2018

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Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (8), p.2212-2217

2016

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Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (39), p.16381-16385

2011

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Anti‐inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid‐induced insulin resistance

The Journal of physiology, 2019-08, Vol.597 (15), p.3885-3903

2019

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31P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism

Diabetes (New York, N.Y.), 2012-10, Vol.61 (11), p.2669-2678

2012

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Effect of a Low-Fat Vegan Diet on Body Weight, Insulin Sensitivity, Postprandial Metabolism, and Intramyocellular and Hepatocellular Lipid Levels in Overweight Adults: A Randomized Clinical Trial

JAMA network open, 2020-11, Vol.3 (11), p.e2025454-e2025454

2020

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Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (33), p.13705-13709

2011

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Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes

Cell metabolism, 2018-01, Vol.27 (1), p.210-217.e3

2018

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Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (48), p.18273-18277

2006

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role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (31), p.12587-12594

2007

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Effect of aging on muscle mitochondrial substrate utilization in humans

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (36), p.11330-11334

2015

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Reversal of Nonalcoholic Hepatic Steatosis, Hepatic Insulin Resistance, and Hyperglycemia by Moderate Weight Reduction in Patients With Type 2 Diabetes

Diabetes (New York, N.Y.), 2005-03, Vol.54 (3), p.603-608

2005

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Hypophosphatemia promotes lower rates of muscle ATP synthesis

The FASEB journal, 2016-10, Vol.30 (10), p.3378-3387

2016

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Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications

Endocrinology (Philadelphia), 2020-04, Vol.161 (4)

2020

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Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents

The Journal of clinical investigation, 2005-12, Vol.115 (12), p.3587-3593

2005

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Molecular Mechanisms of Insulin Resistance in Humans and Their Potential Links With Mitochondrial Dysfunction

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients

Cellular Mechanism by Which Estradiol Protects Female Ovariectomized Mice From High-Fat Diet-Induced Hepatic and Muscle Insulin Resistance

Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications: Potential Role of Alterations in Mitochondrial Function in the Pathogenesis of Insulin Resistance and Type 2 Diabetes

Disassociation of Liver and Muscle Insulin Resistance from Ectopic Lipid Accumulation in Low-Birth-Weight Individuals

Lipid-induced insulin resistance: unravelling the mechanism

Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease

Disordered Lipid Metabolism and the Pathogenesis of Insulin Resistance

Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation

Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

Anti‐inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid‐induced insulin resistance

31P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism

Effect of a Low-Fat Vegan Diet on Body Weight, Insulin Sensitivity, Postprandial Metabolism, and Intramyocellular and Hepatocellular Lipid Levels in Overweight Adults: A Randomized Clinical Trial

Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals

Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes

Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men

role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome

Effect of aging on muscle mitochondrial substrate utilization in humans

Reversal of Nonalcoholic Hepatic Steatosis, Hepatic Insulin Resistance, and Hyperglycemia by Moderate Weight Reduction in Patients With Type 2 Diabetes

Hypophosphatemia promotes lower rates of muscle ATP synthesis

Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents

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