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A review of protocols for brain organoids and applications for disease modeling

STAR protocols, 2023-03, Vol.4 (1), p.101860-101860, Article 101860

2023

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iPSC-derived neural precursor cells engineering GBA1 recovers acid β-glucosidase deficiency and diminishes α-synuclein and neuropathology

Molecular therapy. Methods & clinical development, 2023-06, Vol.29, p.185-201

2023

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Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids

Cell metabolism, 2019-08, Vol.30 (2), p.374-384.e6

2019

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Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency

JHEP reports, 2022-04, Vol.4 (4), p.100446, Article 100446

2022

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Digitalized Human Organoid for Wireless Phenotyping

iScience, 2018-06, Vol.4, p.294-301

2018

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RB Loss Promotes Aberrant Ploidy by Deregulating Levels and Activity of DNA Replication Factors

The Journal of biological chemistry, 2007-08, Vol.282 (33), p.23867-23877

2007

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Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy

Cancer research (Chicago, Ill.), 2005-06, Vol.65 (11), p.4568-4577

2005

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Intravenous infusion of iPSC-derived neural precursor cells increases acid β-glucosidase function in the brain and lessens the neuronopathic phenotype in a mouse model of Gaucher disease

Human molecular genetics, 2019-10, Vol.28 (20), p.3406-3421

2019

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RB status governs differential sensitivity to cytotoxic and molecularly-targeted therapeutic agents

Cell cycle (Georgetown, Tex.), 2008-04, Vol.7 (8), p.1095-1103

2008

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RB Reversibly Inhibits DNA Replication via Two Temporally Distinct Mechanisms

Molecular and Cellular Biology, 2004-06, Vol.24 (12), p.5404-5420

2004

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RB Tumor Suppressive Function in Response to Xenobiotic Hepatocarcinogens

The American journal of pathology, 2014-06, Vol.184 (6), p.1853-1859

2014

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RB Loss Abrogates Cell Cycle Control and Genome Integrity to Promote Liver Tumorigenesis

Gastroenterology (New York, N.Y. 1943), 2007-09, Vol.133 (3), p.976-984

2007

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Unique Impact of RB Loss on Hepatic Proliferation: TUMORIGENIC STRESSES UNCOVER DISTINCT PATHWAYS OF CELL CYCLE CONTROL

The Journal of biological chemistry, 2010-01, Vol.285 (2), p.1089-1096

2010

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RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult

Nucleic acids research, 2004-01, Vol.32 (1), p.25

2004

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Repression of Ah receptor and induction of transforming growth factor-β genes in DEN-induced mouse liver tumors

Toxicology (Amsterdam), 2008-04, Vol.246 (2), p.242-247

2008

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Unique Impact of RB Loss on Hepatic Proliferation

The Journal of biological chemistry, 2010-01, Vol.285 (2), p.1089-1096

2010

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Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents

Oncogene, 2004-05, Vol.23 (23), p.4107-4120

2004

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Modeling neuronopathic Gaucher disease with human patient-specific midbrain organoids

Molecular genetics and metabolism, 2022-02, Vol.135 (2), p.S75-S75

2022

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Intravenous infusion of iPSC-derived neural progenitors expressing GCase ameliorates alpha-synuclein aggregates in a mouse model of Gaucher disease

Molecular genetics and metabolism, 2019-02, Vol.126 (2), p.S116-S116

2019

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Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease

Antiviral research, 2005, Vol.65 (1), p.13-22

2005

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In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease

Antiviral research, 2004-06, Vol.62 (3), p.111-120

2004

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Suppression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: Novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea

Antiviral research, 2002-11, Vol.56 (2), p.167-181

2002

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Analysis of RB action in DNA damage checkpoint response

Methods in molecular biology (Clifton, N.J.), 2004, Vol.281, p.3

2004

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Noncoding Deletions Expose a Novel Gene Critical for Intestinal Function

Nature (London), 2019-06, Vol.571 (7763), p.107-111

2019

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Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells

Journal of visualized experiments, 2016-03 (109)

2016

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A review of protocols for brain organoids and applications for disease modeling

iPSC-derived neural precursor cells engineering GBA1 recovers acid β-glucosidase deficiency and diminishes α-synuclein and neuropathology

Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids

Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency

Digitalized Human Organoid for Wireless Phenotyping

RB Loss Promotes Aberrant Ploidy by Deregulating Levels and Activity of DNA Replication Factors

Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy

Intravenous infusion of iPSC-derived neural precursor cells increases acid β-glucosidase function in the brain and lessens the neuronopathic phenotype in a mouse model of Gaucher disease

RB status governs differential sensitivity to cytotoxic and molecularly-targeted therapeutic agents

RB Reversibly Inhibits DNA Replication via Two Temporally Distinct Mechanisms

RB Tumor Suppressive Function in Response to Xenobiotic Hepatocarcinogens

RB Loss Abrogates Cell Cycle Control and Genome Integrity to Promote Liver Tumorigenesis

Unique Impact of RB Loss on Hepatic Proliferation: TUMORIGENIC STRESSES UNCOVER DISTINCT PATHWAYS OF CELL CYCLE CONTROL

RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult

Repression of Ah receptor and induction of transforming growth factor-β genes in DEN-induced mouse liver tumors

Unique Impact of RB Loss on Hepatic Proliferation

Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents

Modeling neuronopathic Gaucher disease with human patient-specific midbrain organoids

Intravenous infusion of iPSC-derived neural progenitors expressing GCase ameliorates alpha-synuclein aggregates in a mouse model of Gaucher disease

Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease

In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease

Suppression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: Novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea

Analysis of RB action in DNA damage checkpoint response

Noncoding Deletions Expose a Novel Gene Critical for Intestinal Function

Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells

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