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Cryo-EM Structure of the Open Human Ether-à-go-go-Related K+ Channel hERG

Cell, 2017-04, Vol.169 (3), p.422-430.e10

2017

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Structural Basis of Human KCNQ1 Modulation and Gating

Cell, 2020-01, Vol.180 (2), p.340-347.e9

2020

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Structures of the Human HCN1 Hyperpolarization-Activated Channel

Cell, 2017-01, Vol.168 (1-2), p.111-120.e11

2017

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Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

Nature (London), 2014-12, Vol.516 (7529), p.126-130

2014

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Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanism

Science (American Association for the Advancement of Science), 2016-08, Vol.353 (6300), p.664-669

2016

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Structure-based membrane dome mechanism for Piezo mechanosensitivity

eLife, 2017-12, Vol.6

2017

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Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures

Science (American Association for the Advancement of Science), 2018-05, Vol.360 (6388), p.508-513

2018

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X-ray structure of the mammalian GIRK2-βγ G-protein complex

Nature (London), 2013-06, Vol.498 (7453), p.190-197

2013

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Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium

Cell, 2011-09, Vol.147 (1), p.199-208

2011

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Structure of the CLC-1 chloride channel from Homo sapiens

eLife, 2018-05, Vol.7

2018

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Potassium Channels and the Atomic Basis of Selective Ion Conduction (Nobel Lecture)

Angewandte Chemie (International ed.), 2004-08, Vol.43 (33), p.4265-4277

MacKinnon, Roderick

2004

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Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel

Nature (London), 2017-01, Vol.541 (7635), p.46-51

2017

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Potassium channels

FEBS letters, 2003-11, Vol.555 (1), p.62-65

MacKinnon, Roderick

2003

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Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+channels

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (9), p.3614-3619

2014

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Structural Titration of Slo2.2, a Na+-Dependent K+ Channel

Cell, 2017-01, Vol.168 (3), p.390-399.e11

2017

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Structural basis for gating the high-conductance Ca2+-activated K+ channel

Nature (London), 2017-01, Vol.541 (7635), p.52-57

2017

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Piezo's membrane footprint and its contribution to mechanosensitivity

eLife, 2018-11, Vol.7

2018

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Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

Nature (London), 2011-08, Vol.477 (7365), p.495-498

2011

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Molecular structure of human KATP in complex with ATP and ADP

eLife, 2017-12, Vol.6

2017

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Structure of a CLC chloride ion channel by cryo-electron microscopy

Nature (London), 2017-01, Vol.541 (7638), p.500-505

2017

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Crystal Structure of the Human K2P TRAAK, a Lipid-and Mechano-Sensitive K⁺ Ion Channel

Science (American Association for the Advancement of Science), 2012-01, Vol.335 (6067), p.436-441

2012

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Voltage-dependent K⁺ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (49), p.19276-19281

2008

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Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology

eLife, 2019-11, Vol.8

2019

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Gating Charge Transfer Center in Voltage Sensors

Science (American Association for the Advancement of Science), 2010-04, Vol.328 (5974), p.67-73

2010

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Molecular basis of signaling specificity between GIRK channels and GPCRs

eLife, 2018-12, Vol.7

2018

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Cryo-EM Structure of the Open Human Ether-à-go-go-Related K+ Channel hERG

Structural Basis of Human KCNQ1 Modulation and Gating

Structures of the Human HCN1 Hyperpolarization-Activated Channel

Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanism

Structure-based membrane dome mechanism for Piezo mechanosensitivity

Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures

X-ray structure of the mammalian GIRK2-βγ G-protein complex

Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium

Structure of the CLC-1 chloride channel from Homo sapiens

Potassium Channels and the Atomic Basis of Selective Ion Conduction (Nobel Lecture)

Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel

Potassium channels

Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+channels

Structural Titration of Slo2.2, a Na+-Dependent K+ Channel

Structural basis for gating the high-conductance Ca2+-activated K+ channel

Piezo's membrane footprint and its contribution to mechanosensitivity

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

Molecular structure of human KATP in complex with ATP and ADP

Structure of a CLC chloride ion channel by cryo-electron microscopy

Crystal Structure of the Human K2P TRAAK, a Lipid-and Mechano-Sensitive K⁺ Ion Channel

Voltage-dependent K⁺ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane

Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology

Gating Charge Transfer Center in Voltage Sensors

Molecular basis of signaling specificity between GIRK channels and GPCRs

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