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Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics

Molecular therapy, 2016-04, Vol.24 (4), p.707-718

2016

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The Interactome of the Glucocorticoid Receptor and Its Influence on the Actions of Glucocorticoids in Combatting Inflammatory and Infectious Diseases

Microbiology and molecular biology reviews, 2016-06, Vol.80 (2), p.495-522

2016

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The Zinc-Finger Domain Containing Protein ZC4H2 Interacts with TRPV4, Enhancing Channel Activity and Turnover at the Plasma Membrane

International journal of molecular sciences, 2020-05, Vol.21 (10), p.3556

2020

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Abrogation of the Brd4-Positive Transcription Elongation Factor b Complex by Papillomavirus E2 Protein Contributes to Viral Oncogene Repression

Journal of Virology, 2010-01, Vol.84 (1), p.76-87

2010

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RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding

Journal of cell science, 2011-03, Vol.124 (6), p.921-932

2011

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Trapping mammalian protein complexes in viral particles

Nature communications, 2016-04, Vol.7 (1), p.11416-11416, Article 11416

2016

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RNF41 interacts with the VPS52 subunit of the GARP and EARP complexes

PloS one, 2017-05, Vol.12 (5), p.e0178132-e0178132

2017

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Protein-protein interactions: network analysis and applications in drug discovery

Current pharmaceutical design, 2012, Vol.18 (30), p.4619

2012

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Opposed regulation of type I IFN‐induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2

The FASEB journal, 2012-01, Vol.26 (1), p.240-249

2012

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Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Scientific reports, 2017-08, Vol.7 (1), p.8941-15, Article 8941

2017

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Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation

PloS one, 2013-07, Vol.8 (7), p.e69115

2013

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MAPPIT: A protein interaction toolbox built on insights in cytokine receptor signaling

Cytokine & growth factor reviews, 2011-10, Vol.22 (5), p.321-329

2011

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Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease

Molecular neurodegeneration, 2018-09, Vol.13 (1), p.50-50, Article 50

2018

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Caspase-1 targets the TLR adaptor Mal at a crucial TIR-domain interaction site

Journal of cell science, 2010-01, Vol.123 (2), p.256-265

2010

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Strategies towards high-quality binary protein interactome maps

Journal of proteomics, 2010-06, Vol.73 (8), p.1415-1420

2010

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Array MAPPIT: High-Throughput Interactome Analysis in Mammalian Cells

Journal of proteome research, 2009-02, Vol.8 (2), p.877-886

2009

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Reverse MAPPIT detects disruptors of protein-protein interactions in human cells

Nature protocols, 2006-06, Vol.1 (1), p.92-97

2006

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MAPPIT as a high-throughput screening assay for modulators of protein-protein interactions in HIV and HCV

Methods in molecular biology (Clifton, N.J.), 2012-01, Vol.812, p.295

2012

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A "Clickable" MTX Reagent as a Practical Tool for Profiling Small-Molecule-Intracellular Target Interactions via MASPIT

ChemMedChem, 2013-03, Vol.8 (3), p.521-526

2013

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Mammalian two-hybrids come of age

Trends in biochemical sciences (Amsterdam. Regular ed.), 2009-11, Vol.34 (11), p.579-588

2009

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MAPPIT (MAmmalian Protein–Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells

Journal of virological methods, 2008-10, Vol.153 (1), p.7-15

2008

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KISS: A Mammalian Two-Hybrid Method for In Situ Analysis of Protein-Protein Interactions

Methods in molecular biology (Clifton, N.J.), 2018, Vol.1794, p.269

2018

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MAPPIT, a mammalian two-hybrid method for in-cell detection of protein-protein interactions

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1278, p.447

2015

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Srchi13, a Novel Early Nodulin from Sesbania rostrata, Is Related to Acidic Class III Chitinases

The Plant cell, 1998-06, Vol.10 (6), p.905-915

1998

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The Role of Interacting Proteins in TRPV4 Channelopathies

Biophysical journal, 2016-02, Vol.110 (3), p.286a-286a

2016

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Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics

The Interactome of the Glucocorticoid Receptor and Its Influence on the Actions of Glucocorticoids in Combatting Inflammatory and Infectious Diseases

The Zinc-Finger Domain Containing Protein ZC4H2 Interacts with TRPV4, Enhancing Channel Activity and Turnover at the Plasma Membrane

Abrogation of the Brd4-Positive Transcription Elongation Factor b Complex by Papillomavirus E2 Protein Contributes to Viral Oncogene Repression

RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding

Trapping mammalian protein complexes in viral particles

RNF41 interacts with the VPS52 subunit of the GARP and EARP complexes

Protein-protein interactions: network analysis and applications in drug discovery

Opposed regulation of type I IFN‐induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2

Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation

MAPPIT: A protein interaction toolbox built on insights in cytokine receptor signaling

Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease

Caspase-1 targets the TLR adaptor Mal at a crucial TIR-domain interaction site

Strategies towards high-quality binary protein interactome maps

Array MAPPIT: High-Throughput Interactome Analysis in Mammalian Cells

Reverse MAPPIT detects disruptors of protein-protein interactions in human cells

MAPPIT as a high-throughput screening assay for modulators of protein-protein interactions in HIV and HCV

A "Clickable" MTX Reagent as a Practical Tool for Profiling Small-Molecule-Intracellular Target Interactions via MASPIT

Mammalian two-hybrids come of age

MAPPIT (MAmmalian Protein–Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells

KISS: A Mammalian Two-Hybrid Method for In Situ Analysis of Protein-Protein Interactions

MAPPIT, a mammalian two-hybrid method for in-cell detection of protein-protein interactions

Srchi13, a Novel Early Nodulin from Sesbania rostrata, Is Related to Acidic Class III Chitinases

The Role of Interacting Proteins in TRPV4 Channelopathies

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