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R1507, a Monoclonal Antibody to the Insulin-Like Growth Factor 1 Receptor, in Patients With Recurrent or Refractory Ewing Sarcoma Family of Tumors: Results of a Phase II Sarcoma Alliance for Research Through Collaboration Study

Journal of clinical oncology, 2011-12, Vol.29 (34), p.4541-4547

2011

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R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis

PloS one, 2011-10, Vol.6 (10), p.e26060

2011

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Development of tetravalent IgG1 dual targeting IGF-1R–EGFR antibodies with potent tumor inhibition

Archives of biochemistry and biophysics, 2012-10, Vol.526 (2), p.206-218

2012

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Structural Basis for the Regulation of Insulin-like Growth Factors by IGF Binding Proteins

Structure (London), 2005, Vol.13 (1), p.155-167

2005

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A Novel Glycoengineered Bispecific Antibody Format for Targeted Inhibition of Epidermal Growth Factor Receptor (EGFR) and Insulin-like Growth Factor Receptor Type I (IGF-1R) Demonstrating Unique Molecular Properties

The Journal of biological chemistry, 2014-07, Vol.289 (27), p.18693-18706

2014

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Vγ9Vδ2 T Cells: Can We Re-Purpose a Potent Anti-Infection Mechanism for Cancer Therapy?

Cells (Basel, Switzerland), 2020-03, Vol.9 (4), p.829

2020

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Selective Tumor Cell Apoptosis and Tumor Regression in CDH17-Positive Colorectal Cancer Models using BI 905711, a Novel Liver-Sparing TRAILR2 Agonist

Molecular cancer therapeutics, 2021-01, Vol.20 (1), p.96-108

2021

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Abstract 2051: BI 905711, a novel CDH17-targeting TRAILR2 agonist, effectively triggers tumor cell apoptosis and tumor regressions selectively in CDH17-positive colorectal cancer models

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2051-2051

2019

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Abstract 710: Kinetic of phosphoproteins in the PI3K and MAPK pathway reflect responsiveness of Ewing's Sarcoma cells to R1507, a human IgG1 Mab that binds IGF-IR

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.710-710

2010

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Short-hairpin-RNA-mediated silencing of fucosyltransferase 8 in Chinese-hamster ovary cells for the production of antibodies with enhanced antibody immune effector function

Biotechnology and applied biochemistry, 2009-05, Vol.53 (1), p.31-37

2009

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Abstract LB-397: Functional characterization of IGF-1R antibodies and possible implications for clinical safety and efficacy

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.LB-397-LB-397

2011

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Abstract 1755: Sensitization of radiotherapy and chemotherapy by adjunction of R1507 (anti-IGF-1R monoclonal antibody) in small cell lung cancer cell lines: Opportunity of translating the triple combination R1507-Cisplatin-radiotherapy

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.1755-1755

2011

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Abstract LB-212: XGFR, an Fc-engineered dual signaling inhibitor targeting IGF-1R and EGFR

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.LB-212-LB-212

2011

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The Preprotein Translocation Channel of the Outer Membrane of Mitochondria

Cell, 1998-06, Vol.93 (6), p.1009-1019

1998

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NMR Spectroscopy Reveals the Solution Dimerization Interface of p53 Core Domains Bound to Their Consensus DNA

The Journal of biological chemistry, 2001-12, Vol.276 (52), p.49020-49027

2001

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Design and Crystal Structures of Protein Kinase B-Selective Inhibitors in Complex with Protein Kinase A and Mutants

Journal of medicinal chemistry, 2005-01, Vol.48 (1), p.163-170

2005

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High Thermostability and Lack of Cooperative DNA Binding Distinguish the p63 Core Domain from the Homologous Tumor Suppressor p53

The Journal of biological chemistry, 2001-10, Vol.276 (40), p.37390-37401

2001

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Dynamics of the TOM Complex of Mitochondria during Binding and Translocation of Preproteins

Molecular and Cellular Biology, 1998-09, Vol.18 (9), p.5256-5262

1998

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Assembly of Tom6 and Tom7 into the TOM core complex of Neurospora crassa

The Journal of biological chemistry, 2001-05, Vol.276 (21), p.17679-17685

2001

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‘Sheltered disruption’ of Neurospora crassa MOM22, an essential component of the mitochondrial protein import complex

The EMBO journal, 1995-03, Vol.14 (6), p.1099-1108

1995

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Sequence of the nuclear ATP synthase subunit 9 gene of Podospora anserina: lack of similarity to the mitochondrial genome

Current genetics, 1991-09, Vol.20 (4), p.349-351

1991

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R1507, a Monoclonal Antibody to the Insulin-Like Growth Factor 1 Receptor, in Patients With Recurrent or Refractory Ewing Sarcoma Family of Tumors: Results of a Phase II Sarcoma Alliance for Research Through Collaboration Study

R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis

Development of tetravalent IgG1 dual targeting IGF-1R–EGFR antibodies with potent tumor inhibition

Structural Basis for the Regulation of Insulin-like Growth Factors by IGF Binding Proteins

A Novel Glycoengineered Bispecific Antibody Format for Targeted Inhibition of Epidermal Growth Factor Receptor (EGFR) and Insulin-like Growth Factor Receptor Type I (IGF-1R) Demonstrating Unique Molecular Properties

Vγ9Vδ2 T Cells: Can We Re-Purpose a Potent Anti-Infection Mechanism for Cancer Therapy?

Selective Tumor Cell Apoptosis and Tumor Regression in CDH17-Positive Colorectal Cancer Models using BI 905711, a Novel Liver-Sparing TRAILR2 Agonist

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

Abstract 2051: BI 905711, a novel CDH17-targeting TRAILR2 agonist, effectively triggers tumor cell apoptosis and tumor regressions selectively in CDH17-positive colorectal cancer models

Abstract 710: Kinetic of phosphoproteins in the PI3K and MAPK pathway reflect responsiveness of Ewing's Sarcoma cells to R1507, a human IgG1 Mab that binds IGF-IR

Short-hairpin-RNA-mediated silencing of fucosyltransferase 8 in Chinese-hamster ovary cells for the production of antibodies with enhanced antibody immune effector function

Abstract LB-397: Functional characterization of IGF-1R antibodies and possible implications for clinical safety and efficacy

Abstract 1755: Sensitization of radiotherapy and chemotherapy by adjunction of R1507 (anti-IGF-1R monoclonal antibody) in small cell lung cancer cell lines: Opportunity of translating the triple combination R1507-Cisplatin-radiotherapy

Abstract LB-212: XGFR, an Fc-engineered dual signaling inhibitor targeting IGF-1R and EGFR

The Preprotein Translocation Channel of the Outer Membrane of Mitochondria

NMR Spectroscopy Reveals the Solution Dimerization Interface of p53 Core Domains Bound to Their Consensus DNA

Design and Crystal Structures of Protein Kinase B-Selective Inhibitors in Complex with Protein Kinase A and Mutants

High Thermostability and Lack of Cooperative DNA Binding Distinguish the p63 Core Domain from the Homologous Tumor Suppressor p53

Dynamics of the TOM Complex of Mitochondria during Binding and Translocation of Preproteins

Assembly of Tom6 and Tom7 into the TOM core complex of Neurospora crassa

‘Sheltered disruption’ of Neurospora crassa MOM22, an essential component of the mitochondrial protein import complex

Sequence of the nuclear ATP synthase subunit 9 gene of Podospora anserina: lack of similarity to the mitochondrial genome

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