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Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

Cell, 2010-03, Vol.140 (6), p.900-917

Hotamisligil, Gökhan S.

2010

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Calcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes

Cell metabolism, 2015-09, Vol.22 (3), p.381-397

2015

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Inflammatory mechanisms in obesity

Annual review of immunology, 2011-04, Vol.29 (1), p.415-445

2011

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FABP4 Attenuates PPARγ and Adipogenesis and Is Inversely Correlated With PPARγ in Adipose Tissues

Diabetes (New York, N.Y.), 2014-03, Vol.63 (3), p.900-911

2014

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Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss

Diabetes (New York, N.Y.), 2009-03, Vol.58 (3), p.693-700

2009

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Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

Circulation research, 2010-09, Vol.107 (5), p.579-591

2010

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The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling

Cell metabolism, 2012-05, Vol.15 (5), p.623-634

2012

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Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses

Journal of lipid research, 2019-04, Vol.60 (4), p.734-740

2019

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Role of Endoplasmic Reticulum Stress and c-Jun NH2-Terminal Kinase Pathways in Inflammation and Origin of Obesity and Diabetes

Diabetes (New York, N.Y.), 2005-12, Vol.54 (suppl 2), p.S73-S78

HOTAMISLIGIL, Gökhan S

2005

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Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

Cell metabolism, 2010-06, Vol.11 (6), p.467-478

2010

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Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

Science (American Association for the Advancement of Science), 2006-08, Vol.313 (5790), p.1137-1140

2006

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S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction

Science (American Association for the Advancement of Science), 2015-07, Vol.349 (6247), p.500-506

2015

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Potential role for snoRNAs in PKR activation during metabolic stress

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.5023-5028

2015

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The interaction of hepatic lipid and glucose metabolism in liver diseases

Journal of hepatology, 2012-04, Vol.56 (4), p.952-964

2012

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Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways

Cell metabolism, 2011-07, Vol.14 (1), p.21-32

2011

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Trans-palmitoleic acid, metabolic risk factors, and new-onset diabetes in U.S. adults: a cohort study

Annals of internal medicine, 2010-12, Vol.153 (12), p.790

2010

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Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Science (American Association for the Advancement of Science), 2004-10, Vol.306 (5695), p.457-461

2004

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Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle

Cell reports (Cambridge), 2016-01, Vol.14 (3), p.422-428

2016

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Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

Cell, 2008-09, Vol.134 (6), p.933-944

2008

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Serum fatty acid-binding protein 4 is a predictor of cardiovascular events in end-stage renal disease

PloS one, 2011-11, Vol.6 (11), p.e27356-e27356

2011

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Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity

Journal of lipid research, 2015-02, Vol.56 (2), p.423-434

2015

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Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production

Cell metabolism, 2013-05, Vol.17 (5), p.768-778

2013

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Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice

Diabetes (New York, N.Y.), 2014-02, Vol.63 (2), p.526-534

2014

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Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis

Molecular cell, 2008-03, Vol.29 (5), p.541-551

2008

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Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women

Diabetes (New York, N.Y.), 2010-08, Vol.59 (8), p.1899-1905

2010

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Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

Calcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes

Inflammatory mechanisms in obesity

FABP4 Attenuates PPARγ and Adipogenesis and Is Inversely Correlated With PPARγ in Adipose Tissues

Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling

Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses

Role of Endoplasmic Reticulum Stress and c-Jun NH2-Terminal Kinase Pathways in Inflammation and Origin of Obesity and Diabetes

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction

Potential role for snoRNAs in PKR activation during metabolic stress

The interaction of hepatic lipid and glucose metabolism in liver diseases

Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways

Trans-palmitoleic acid, metabolic risk factors, and new-onset diabetes in U.S. adults: a cohort study

Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle

Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

Serum fatty acid-binding protein 4 is a predictor of cardiovascular events in end-stage renal disease

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity

Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production

Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice

Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis

Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women

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