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Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy

Cell reports (Cambridge), 2024-05, Vol.43 (5), p.114141, Article 114141

2024

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328 Batf3 dendritic cells and 4–1BB/4–1BB ligand axis are required at the effector phase within the tumor microenvironment for anti-PD-L1 efficacy

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A354-A354

2021

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664 Pulmonary priming of tumor-reactive CD8+ T cells by DC1 is impaired by regulatory T cells

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A692-A692

2021

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183 Overcoming immunotherapy resistance in T cell-inflamed lung cancer

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A197-A197

2020

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517 Splenic tumor-reactive CD8+ T cells are endowed with a unique potential for expansion and are the dominant source of systemic anti-tumor immunity after ICB therapy

Journal for immunotherapy of cancer, 2022, Vol.10 (Suppl 2), p.A542-A542

2022

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The particulars on peptides

Nature (London), 1996-02, Vol.379 (6564), p.471-472

HORTON>, BRENDAN

1996

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Abstract B154: Immune surveillance is thwarted by tumor-cell intrinsic β-catenin signaling

Cancer immunology research, 2016-01, Vol.4 (1_Supplement), p.B154-B154

2016

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303 Non-functional T cell responses in non-small cell lung cancer are induced during tumor antigen-specific T cell priming in the mediastinal lymph node

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A326-A326

2021

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Trade and Transport Facilitation Assessment: A Practical Toolkit for Country Implementation

1, 2010

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Immune surveillance is thwarted by tumor-cell intrinsic beta-catenin signaling

Journal for immunotherapy of cancer, 2015-11, Vol.3 (Suppl 2), p.P418-P418, Article P418

2015

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Abstract 2618: Agonist antibodies targeting OX40 and GITR enhance the activity of the IDO1-selective inhibitor epacadostat in preclinical models

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2618-2618

2017

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Intratumoral CD8+ T-Cell Apoptosis is a Major Component of T-Cell Dysfunction and Impedes Anti-Tumor Immunity

Cancer immunology research, 2017-11, Vol.6 (1), p.14-24

2017

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Polycythemia Vera and Chronic Idiopathic Myelofibrosis CD34+ Cells Preferentially Traffic to Splenic Niches

Blood, 2012-11, Vol.120 (21), p.1750-1750

2012

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LAG-3 and 4-1BB identify dysfunctional antigen-specific T cells in the tumor microenvironment and combinatorial LAG-3/4-1BB targeting gives synergistic tumor control

Journal for immunotherapy of cancer, 2015-11, Vol.3 (Suppl 2), p.P328-P328, Article P328

2015

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Applications matter

Nature (London), 2002-03, Vol.416 (6877), p.4-5

Horton, Brendan

2002

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Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment

Journal for immunotherapy of cancer, 2015-11, Vol.3 (Suppl 2), p.O10-O10, Article O10

2015

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Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors

Journal for immunotherapy of cancer, 2014-11, Vol.2 (Suppl 3), p.P213-P213, Article P213

2014

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Passing the baton?

Nature (London), 2000-01, Vol.403 (6768), p.463-463

Horton, Brendan

2000

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Creative fusion of many minds

Nature (London), 2000-01, Vol.403 (6768), p.464-464

Horton, Brendan

2000

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First write your business plan

Nature (London), 1999-05, Vol.399 (6732), p.176-176

Horton, Brendan

1999

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Getting into automatic gear

Nature (London), 1999-01, Vol.397 (6717), p.369-370

Horton, Brendan

1999

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Cell biology smorgasbord

Nature (London), 1998-12, Vol.396 (6711), p.599-602

Horton, Brendan

1998

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Ways to handle DNA

Nature (London), 1998-10, Vol.395 (6703), p.725-726

Horton, Brendan

1998

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A light at the end of the tube

Nature (London), 1998-07, Vol.394 (6692), p.507-507

Horton, Brendan

1998

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Refining your image acquisition

Nature (London), 1998-07, Vol.394 (6688), p.102-102

Horton, Brendan

1998

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Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy

328 Batf3 dendritic cells and 4–1BB/4–1BB ligand axis are required at the effector phase within the tumor microenvironment for anti-PD-L1 efficacy

664 Pulmonary priming of tumor-reactive CD8+ T cells by DC1 is impaired by regulatory T cells

183 Overcoming immunotherapy resistance in T cell-inflamed lung cancer

517 Splenic tumor-reactive CD8+ T cells are endowed with a unique potential for expansion and are the dominant source of systemic anti-tumor immunity after ICB therapy

The particulars on peptides

Abstract B154: Immune surveillance is thwarted by tumor-cell intrinsic β-catenin signaling

303 Non-functional T cell responses in non-small cell lung cancer are induced during tumor antigen-specific T cell priming in the mediastinal lymph node

Trade and Transport Facilitation Assessment: A Practical Toolkit for Country Implementation

Immune surveillance is thwarted by tumor-cell intrinsic beta-catenin signaling

Abstract 2618: Agonist antibodies targeting OX40 and GITR enhance the activity of the IDO1-selective inhibitor epacadostat in preclinical models

Intratumoral CD8+ T-Cell Apoptosis is a Major Component of T-Cell Dysfunction and Impedes Anti-Tumor Immunity

Polycythemia Vera and Chronic Idiopathic Myelofibrosis CD34+ Cells Preferentially Traffic to Splenic Niches

LAG-3 and 4-1BB identify dysfunctional antigen-specific T cells in the tumor microenvironment and combinatorial LAG-3/4-1BB targeting gives synergistic tumor control

Applications matter

Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment

Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors

Passing the baton?

Creative fusion of many minds

First write your business plan

Getting into automatic gear

Cell biology smorgasbord

Ways to handle DNA

A light at the end of the tube

Refining your image acquisition

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Suchergebnisse filtern