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Modulation of Cardiac Contractility by the Phopholamban/SERCA2a Regulatome

Circulation research, 2012-06, Vol.110 (12), p.1646-1660

2012

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Human Cardiac Gene Therapy

Circulation research, 2018-08, Vol.123 (5), p.601-613

2018

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Altered Myocardial Calcium Cycling and Energetics in Heart Failure—A Rational Approach for Disease Treatment

Cell metabolism, 2015-02, Vol.21 (2), p.183-194

2015

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Potential of gene therapy as a treatment for heart failure

The Journal of clinical investigation, 2013-01, Vol.123 (1), p.53-61

Hajjar, Roger J

2013

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Gene therapy for the treatment of heart failure: promise postponed

European heart journal, 2016-06, Vol.37 (21), p.1651-1658

2016

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Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration

Circulation (New York, N.Y.), 2020-04, Vol.141 (15), p.1249-1265

2020

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Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders

The Journal of biological chemistry, 2016-03, Vol.291 (10), p.5185-5198

2016

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Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure

Circulation research, 2019-04, Vol.124 (9), p.e63-e80

2019

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Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis

Journal of the American College of Cardiology, 2016-04, Vol.67 (13), p.1556-1568

2016

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Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes

PloS one, 2011-11, Vol.6 (11), p.e27417-e27417

2011

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Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling

Circulation research, 2018-01, Vol.122 (1), p.167-183

2018

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Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy

Science translational medicine, 2012-04, Vol.4 (130), p.130ra47

2012

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Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair

Nature medicine, 2007-08, Vol.13 (8), p.962-969

2007

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Neutralizing Antibodies Against AAV Serotypes 1, 2, 6, and 9 in Sera of Commonly Used Animal Models

Molecular therapy, 2012-01, Vol.20 (1), p.73-83

2012

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Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways

The Journal of biological chemistry, 2011-05, Vol.286 (21), p.18465-18473

2011

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Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial

Journal of cardiac failure, 2009-04, Vol.15 (3), p.171-181

2009

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Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapy

Human gene therapy. Part B. Methods, 2013-04, Vol.24 (2), p.59

2013

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Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium

The FASEB journal, 2014-02, Vol.28 (2), p.644-654

2014

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Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies

Biological research, 2021-08, Vol.54 (1), p.1-23, Article 23

2021

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In vivo tracking of stem cells for clinical trials in cardiovascular disease

Circulation (New York, N.Y.), 2004-11, Vol.110 (21), p.3378-3383

2004

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Targeted Sarcoplasmic Reticulum Ca2+ ATPase 2a Gene Delivery to Restore Electrical Stability in the Failing Heart

Circulation (New York, N.Y.), 2012-10, Vol.126 (17), p.2095-2104

2012

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Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2675

2023

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Current Methods in Cardiac Gene Therapy: Overview

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1521, p.3

2017

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Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle

The Journal of clinical investigation, 2011-03, Vol.121 (3), p.1044-1052

2011

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Direct reprogramming induces vascular regeneration post muscle ischemic injury

Molecular therapy, 2021-10, Vol.29 (10), p.3042-3058

2021

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Modulation of Cardiac Contractility by the Phopholamban/SERCA2a Regulatome

Human Cardiac Gene Therapy

Altered Myocardial Calcium Cycling and Energetics in Heart Failure—A Rational Approach for Disease Treatment

Potential of gene therapy as a treatment for heart failure

Gene therapy for the treatment of heart failure: promise postponed

Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration

Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders

Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure

Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis

Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes

Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy

Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair

Neutralizing Antibodies Against AAV Serotypes 1, 2, 6, and 9 in Sera of Commonly Used Animal Models

Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial

Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapy

Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium

Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies

In vivo tracking of stem cells for clinical trials in cardiovascular disease

Targeted Sarcoplasmic Reticulum Ca2+ ATPase 2a Gene Delivery to Restore Electrical Stability in the Failing Heart

Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy

Current Methods in Cardiac Gene Therapy: Overview

Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle

Direct reprogramming induces vascular regeneration post muscle ischemic injury

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