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Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor

Toxicology letters, 2018-09, Vol.293, p.172-183

2018

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In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers

Toxicology letters, 2018-09, Vol.293, p.190-197

2018

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First asymmetric syntheses of 6-substituted nipecotic acid derivatives

Tetrahedron, 2004-01, Vol.60 (2), p.307-318

2004

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Evaluation of GABA uptake in subcellular fractions of bovine frontal cortex and brainstem

Neuroscience letters, 2004-06, Vol.364 (1), p.53-57

2004

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Synthesis of the Four Stereoisomers of 1-Amino-2-(hydroxymethyl)cyclobutanecarboxylic Acid and Their Biological Evaluation as Ligands for the Glycine Binding Site of the NMDA Receptor

European journal of organic chemistry, 2003-06, Vol.2003 (12), p.2233-2242

2003

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Syntheses of novel pyrazolomorphinans and their binding to mu- and kappa-opioid-receptors

Pharmazie, 1998-02, Vol.53 (2), p.87-90

1998

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Synthesis and resolution of racemic eliprodil and evaluation of the enantiomers of eliprodil as NMDA receptor antagonists

Bioorganic & medicinal chemistry letters, 2000-06, Vol.10 (12), p.1377-1380

2000

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Synthesis of enantiomerically pure 6,10-epoxybenzocycloocten-7-amines with CNS activity

Archiv der Pharmazie (Weinheim), 1992-11, Vol.325 (11), p.733

1992

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Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4

European journal of pharmacology, 2005-09, Vol.519 (1-2), p.43-47

2005

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Synthesis, Pharmacological Investigation and Computational Studies on a Tricyclic Ergoline Analog with Selective Dopamine Autoreceptor Activity

Archiv der Pharmazie (Weinheim), 1995, Vol.328 (7-8), p.609-614

1995

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Tricyclic CNS Active Agents by Intramolecular Oxa-Pictet-Spengler Reaction

Archiv der Pharmazie (Weinheim), 1995, Vol.328 (6), p.487-495

1995

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Synthesis of (S)-3,4-Diaminobutanenitriles as Precursors for 3-Amino-GABA Derivatives

Archiv der Pharmazie (Weinheim), 1995, Vol.328 (3), p.265-268

1995

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Synthesis and CNS-activity of spirocyclic pethidine and prodine analogs

Archiv der Pharmazie (Weinheim), 1993-09, Vol.326 (9), p.513

1993

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[ 3H]ifenprodil binding to NMDA receptors in porcine hippocampal brain membranes

European journal of pharmacology, 2000-04, Vol.394 (2), p.211-219

2000

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Characterisation of the binding of [ 3H]MDL 105,519, a radiolabelled antagonist for the N-methyl- d-aspartate-associated glycine site, to pig cortical brain membranes

Neuroscience letters, 1997-04, Vol.226 (2), p.79-82

1997

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Enteral nutritional support by percutaneous endoscopic gastrostomy in children with congenital heart disease

Pediatric cardiology, 2000-07, Vol.21 (4), p.341-346

2000

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Synthesis and opioid-receptor binding of novel amino-substituted morphan analogues

Archiv der Pharmazie (Weinheim), 2001-09, Vol.334 (8-9), p.284-290

2001

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Competitive Binding Assays Made Easy with a Native Marker and Mass Spectrometric Quantification

Angewandte Chemie (International ed.), 2003-11, Vol.42 (42), p.5235-5237

2003

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ZNS-wirksame Pyrane: Amin- und arylsubstituierte Dioxabicyclooctane

Archiv der Pharmazie (Weinheim), 1994, Vol.327 (7), p.405-412

1994

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Characterisation of [3H]MK-801 Binding and its Cooperative Modulation by PIG Brain Membranes

Journal of receptors and signal transduction, 1996-01, Vol.16 (5-6), p.297-313

1996

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Azagrevellins, Part I. Grevellin analogs with affinity to the N-methyl-D-aspartate (glycine site) receptor, a novel lead structure

Archiv der Pharmazie (Weinheim), 2000-07, Vol.333 (7), p.211-216

2000

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Stereoselective Synthesis and Receptor Binding of Conformationally Restricted and Flexible 2,4-Disubstituted 1,3-Dioxanes Derived from Benzomorphans

Archiv der Pharmazie (Weinheim), 1999-12, Vol.332 (12), p.413-421

1999

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Stereoselective syntheses and CNS activity of novel tricyclic amines

Pharmazie, 1997-02, Vol.52 (2), p.87-91

1997

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Pyrrolidine-2,4-diones with affinity to the N-methyl-D-aspartate (glycine site) receptor, Part II. 5-arylidene-pyrrolidine-2,3,4-trione 3-oximes as NMDA receptor antagonists

Archiv der Pharmazie (Weinheim), 1999-09, Vol.332 (9), p.309-316

1999

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CNS-active pyrans: amine- and aryl- substituted dioxabicyclooctanes

Archiv der Pharmazie (Weinheim), 1994-07, Vol.327 (7), p.405-412

1994

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Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor

In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers

First asymmetric syntheses of 6-substituted nipecotic acid derivatives

Evaluation of GABA uptake in subcellular fractions of bovine frontal cortex and brainstem

Synthesis of the Four Stereoisomers of 1-Amino-2-(hydroxymethyl)cyclobutanecarboxylic Acid and Their Biological Evaluation as Ligands for the Glycine Binding Site of the NMDA Receptor

Syntheses of novel pyrazolomorphinans and their binding to mu- and kappa-opioid-receptors

Synthesis and resolution of racemic eliprodil and evaluation of the enantiomers of eliprodil as NMDA receptor antagonists

Synthesis of enantiomerically pure 6,10-epoxybenzocycloocten-7-amines with CNS activity

Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4

Synthesis, Pharmacological Investigation and Computational Studies on a Tricyclic Ergoline Analog with Selective Dopamine Autoreceptor Activity

Tricyclic CNS Active Agents by Intramolecular Oxa-Pictet-Spengler Reaction

Synthesis of (S)-3,4-Diaminobutanenitriles as Precursors for 3-Amino-GABA Derivatives

Synthesis and CNS-activity of spirocyclic pethidine and prodine analogs

[ 3H]ifenprodil binding to NMDA receptors in porcine hippocampal brain membranes

Characterisation of the binding of [ 3H]MDL 105,519, a radiolabelled antagonist for the N-methyl- d-aspartate-associated glycine site, to pig cortical brain membranes

Enteral nutritional support by percutaneous endoscopic gastrostomy in children with congenital heart disease

Synthesis and opioid-receptor binding of novel amino-substituted morphan analogues

Competitive Binding Assays Made Easy with a Native Marker and Mass Spectrometric Quantification

ZNS-wirksame Pyrane: Amin- und arylsubstituierte Dioxabicyclooctane

Characterisation of [3H]MK-801 Binding and its Cooperative Modulation by PIG Brain Membranes

Azagrevellins, Part I. Grevellin analogs with affinity to the N-methyl-D-aspartate (glycine site) receptor, a novel lead structure

Stereoselective Synthesis and Receptor Binding of Conformationally Restricted and Flexible 2,4-Disubstituted 1,3-Dioxanes Derived from Benzomorphans

Stereoselective syntheses and CNS activity of novel tricyclic amines

Pyrrolidine-2,4-diones with affinity to the N-methyl-D-aspartate (glycine site) receptor, Part II. 5-arylidene-pyrrolidine-2,3,4-trione 3-oximes as NMDA receptor antagonists

CNS-active pyrans: amine- and aryl- substituted dioxabicyclooctanes

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