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Remdesivir for the treatment of Covid-19: the value of biochemical studies

Current opinion in virology, 2021-08, Vol.49, p.81-85

Götte, Matthias

2021

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Direct-acting antiviral agents for hepatitis C: structural and mechanistic insights

Nature reviews. Gastroenterology & hepatology, 2016-06, Vol.13 (6), p.338

2016

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Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

Viruses, 2019-04, Vol.11 (4), p.326

2019

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Zika Virus Hijacks Stress Granule Proteins and Modulates the Host Stress Response

Journal of virology, 2017-08, Vol.91 (16)

2017

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Theoretical investigation of the applicability of the Meservey-Tedrow technique to the surface states of topological insulators

New journal of physics, 2019-12, Vol.21 (12), p.123042

2019

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Recombinant RNA-Dependent RNA Polymerase Complex of Ebola Virus

Scientific reports, 2018-03, Vol.8 (1), p.3970-9, Article 3970

2018

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Pure spin current devices based on ferromagnetic topological insulators

Scientific reports, 2016-10, Vol.6 (1), p.36070-36070, Article 36070

2016

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Conformational Changes Spanning Angstroms to Nanometers via a Combined Protein-Induced Fluorescence Enhancement-Förster Resonance Energy Transfer Method

The journal of physical chemistry. B, 2017-03, Vol.121 (9), p.2039-2048

2017

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Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

Science translational medicine, 2022-08, Vol.14 (656), p.eabo0718

2022

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Resistance patterns associated with HCV NS5A inhibitors provide limited insight into drug binding

Viruses, 2014-11, Vol.6 (11), p.4227-4241

2014

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Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K–specific inhibition

Proceedings of the National Academy of Sciences - PNAS, 2022-07, Vol.119 (27), p.1-e2200260119

2022

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Modular Assembly of Purine-like Bisphosphonates as Inhibitors of HIV‑1 Reverse Transcriptase

Journal of medicinal chemistry, 2014-09, Vol.57 (17), p.7435-7449

2014

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Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases

Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (43), p.26946-26954

2020

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Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein

PLoS neglected tropical diseases, 2020-06, Vol.14 (6), p.e0008283-e0008283

2020

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Contribution of a mutational bias in hepatitis C virus replication to the genetic barrier in the development of drug resistance

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (51), p.20509-20513

2011

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Resistance to nucleotide analogue inhibitors of hepatitis C virus NS5B: mechanisms and clinical relevance

Current opinion in virology, 2014-10, Vol.8, p.104-108

Gotte, Matthias

2014

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Binding Kinetics and Affinities of Heterodimeric versus Homodimeric HIV‑1 Reverse Transcriptase on DNA–DNA Substrates at the Single-Molecule Level

The journal of physical chemistry. B, 2013-04, Vol.117 (16), p.4560-4567

2013

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Binding and Sliding Dynamics of the Hepatitis C Virus Polymerase: Hunting the 3′ Terminus

ACS infectious diseases, 2023-08, Vol.9 (8), p.1488-1498

2023

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Indolopyridones Inhibit Human Immunodeficiency Virus Reverse Transcriptase with a Novel Mechanism of Action

Journal of Virology, 2006-12, Vol.80 (24), p.12283-12292

2006

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Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing

PLoS medicine, 2007-12, Vol.4 (12), p.e346

Gotte, Matthias

2007

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Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (11), p.3475-3480

2015

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HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors

Viruses, 2010-04, Vol.2 (4), p.900-926

2010

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Structural basis for substrate selection by the SARS-CoV-2 replicase

Nature (London), 2023-02, Vol.614 (7949), p.781-787

2023

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Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility

Journal of virology, 2015-04, Vol.89 (8), p.4636-4644

2015

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Handbook of Antimicrobial Resistance

1st ed. 2018, 2017

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Remdesivir for the treatment of Covid-19: the value of biochemical studies

Direct-acting antiviral agents for hepatitis C: structural and mechanistic insights

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

Zika Virus Hijacks Stress Granule Proteins and Modulates the Host Stress Response

Theoretical investigation of the applicability of the Meservey-Tedrow technique to the surface states of topological insulators

Recombinant RNA-Dependent RNA Polymerase Complex of Ebola Virus

Pure spin current devices based on ferromagnetic topological insulators

Conformational Changes Spanning Angstroms to Nanometers via a Combined Protein-Induced Fluorescence Enhancement-Förster Resonance Energy Transfer Method

Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

Resistance patterns associated with HCV NS5A inhibitors provide limited insight into drug binding

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K–specific inhibition

Modular Assembly of Purine-like Bisphosphonates as Inhibitors of HIV‑1 Reverse Transcriptase

Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases

Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein

Contribution of a mutational bias in hepatitis C virus replication to the genetic barrier in the development of drug resistance

Resistance to nucleotide analogue inhibitors of hepatitis C virus NS5B: mechanisms and clinical relevance

Binding Kinetics and Affinities of Heterodimeric versus Homodimeric HIV‑1 Reverse Transcriptase on DNA–DNA Substrates at the Single-Molecule Level

Binding and Sliding Dynamics of the Hepatitis C Virus Polymerase: Hunting the 3′ Terminus

Indolopyridones Inhibit Human Immunodeficiency Virus Reverse Transcriptase with a Novel Mechanism of Action

Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing

Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics

HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors

Structural basis for substrate selection by the SARS-CoV-2 replicase

Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility

Handbook of Antimicrobial Resistance

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