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Acetogenins from Annonaceae: recent progress in isolation, synthesis and mechanisms of action

Natural product reports, 2005-01, Vol.22 (2), p.269-303

2005

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Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase

FEBS letters, 1993-10, Vol.332 (1), p.127-131

1993

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Circumdatin H, a new inhibitor of mitochondrial NADH oxidase, from Aspergillus ochraceus

Journal of antibiotics, 2005-06, Vol.58 (6), p.416-419

2005

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Steady-State Kinetics of the Reduction of Coenzyme Q Analogs by Complex I (NADH:Ubiquinone Oxidoreductase) in Bovine Heart Mitochondria and Submitochondrial Particles

Biochemistry (Easton), 1996-02, Vol.35 (8), p.2705-2716

1996

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Acetogenins from annonaceae, inhibitors of mitochondrial complex I

Phytochemistry, 1996-05, Vol.42 (2), p.253-271

1996

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Specific interactions of monotetrahydrofuranic annonaceous acetogenins as inhibitors of mitochondrial complex I

Chemico-biological interactions, 1999-11, Vol.122 (3), p.171-183

1999

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Inhibitory effects on mitochondrial complex I of semisynthetic mono-Tetrahydrofuran acetogenin derivatives

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (22), p.4101-4105

2003

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Kinetic Characterization of Mitochondrial Complex I Inhibitors Using Annonaceous Acetogenins

Archives of biochemistry and biophysics, 1999-09, Vol.369 (1), p.119-126

1999

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Semisynthesis of Antitumoral Acetogenins: SAR of Functionalized Alkyl-Chain Bis-Tetrahydrofuranic Acetogenins, Specific Inhibitors of Mitochondrial Complex I

Journal of medicinal chemistry, 2000-12, Vol.43 (25), p.4793-4800

2000

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Guanaconetins, new antitumoral acetogenins, mitochondrial complex I and tumor cell growth inhibitors

Bioorganic & medicinal chemistry, 2006-02, Vol.14 (4), p.1089-1094

2006

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Tigliane diterpenes from the latex of Euphorbia obtusifolia with inhibitory activity on the mammalian mitochondrial respiratory chain

Journal of ethnopharmacology, 2003-04, Vol.85 (2), p.279-282

2003

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3-Acetylaltholactone and related styryl-lactones, mitochondrial respiratory chain inhibitors

Phytochemistry (Oxford), 2000-06, Vol.54 (3), p.311-315

2000

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New Evidence for the Multiplicity of Ubiquinone- and Inhibitor-Binding Sites in the Mitochondrial Complex I

Archives of biochemistry and biophysics, 2000-09, Vol.381 (2), p.241-246

2000

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Semisynthesis of new tetrahydrofuranic alkyl ester and furano-pyrone derivatives as inhibitors of the mitochondrial complex I

Tetrahedron, 2002-02, Vol.58 (7), p.1335-1342

2002

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Novel Inhibitors of Mitochondrial Respiratory Chain: Endoperoxides from the Marine Tunicate Stolonica socialis

Journal of medicinal chemistry, 2001-07, Vol.44 (14), p.2362-2365

2001

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In vitro antitumor SAR of threo/cis/threo/cis/erythro bis-THF acetogenins: correlations with their inhibition of mitochondrial Complex I

Oncology research, 2003-01, Vol.13 (12), p.521

2003

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Novel Inhibitors of the Mitochondrial Respiratory Chain: Oximes and Pyrrolines Isolated from Penicillium brevicompactum and Synthetic Analogues

Journal of agricultural and food chemistry, 2005-10, Vol.53 (21), p.8296-8301

2005

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γ-Lactone-functionalized antitumoral acetogenins are the most potent inhibitors of Mitochondrial Complex I

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (5), p.681-684

2001

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Jatrophane Diterpenes from the Latex of Euphorbia obtusifolia with Inhibitory Activity on the Mammalian Mitochondrial Respiratory Chain

Planta medica, 2003-02, Vol.69 (2), p.177-178

2003

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Cherimolin-1, New Selective Inhibitor of the First Energy-Coupling Site of the NADH:Ubiquinone Oxidoreductase (Complex I)

Biochemical and biophysical research communications, 1997-11, Vol.240 (1), p.234-238

1997

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Bisbenzyltetrahydroisoquinolines, a new class of inhibitors of the mitochondrial respiratory chain complex I

Planta medica, 2004-03, Vol.70 (3), p.266-268

2004

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Effects of vitamin A deficiency on mitochondrial function in rat liver and heart

British journal of nutrition, 2000-12, Vol.84 (6), p.927-934

2000

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Enantiospecific Semisynthesis of (+)-Almuheptolide-A, a Novel Natural Heptolide Inhibitor of the Mammalian Mitochondrial Respiratory Chain

Journal of medicinal chemistry, 1998-12, Vol.41 (26), p.5158-5166

1998

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Complex I and Complex III of Mitochondria Have Common Inhibitors Acting as Ubiquinone Antagonists

Biochemical and biophysical research communications, 1993-02, Vol.190 (3), p.1090-1096

1993

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Rollimembrin, a novel acetogenin inhibitor of mammalian mitochondrial complex I

Bioorganic & medicinal chemistry letters, 1997-05, Vol.7 (9), p.1113-1118

1997

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Acetogenins from Annonaceae: recent progress in isolation, synthesis and mechanisms of action

Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase

Circumdatin H, a new inhibitor of mitochondrial NADH oxidase, from Aspergillus ochraceus

Steady-State Kinetics of the Reduction of Coenzyme Q Analogs by Complex I (NADH:Ubiquinone Oxidoreductase) in Bovine Heart Mitochondria and Submitochondrial Particles

Acetogenins from annonaceae, inhibitors of mitochondrial complex I

Specific interactions of monotetrahydrofuranic annonaceous acetogenins as inhibitors of mitochondrial complex I

Inhibitory effects on mitochondrial complex I of semisynthetic mono-Tetrahydrofuran acetogenin derivatives

Kinetic Characterization of Mitochondrial Complex I Inhibitors Using Annonaceous Acetogenins

Semisynthesis of Antitumoral Acetogenins: SAR of Functionalized Alkyl-Chain Bis-Tetrahydrofuranic Acetogenins, Specific Inhibitors of Mitochondrial Complex I

Guanaconetins, new antitumoral acetogenins, mitochondrial complex I and tumor cell growth inhibitors

Tigliane diterpenes from the latex of Euphorbia obtusifolia with inhibitory activity on the mammalian mitochondrial respiratory chain

3-Acetylaltholactone and related styryl-lactones, mitochondrial respiratory chain inhibitors

New Evidence for the Multiplicity of Ubiquinone- and Inhibitor-Binding Sites in the Mitochondrial Complex I

Semisynthesis of new tetrahydrofuranic alkyl ester and furano-pyrone derivatives as inhibitors of the mitochondrial complex I

Novel Inhibitors of Mitochondrial Respiratory Chain: Endoperoxides from the Marine Tunicate Stolonica socialis

In vitro antitumor SAR of threo/cis/threo/cis/erythro bis-THF acetogenins: correlations with their inhibition of mitochondrial Complex I

Novel Inhibitors of the Mitochondrial Respiratory Chain: Oximes and Pyrrolines Isolated from Penicillium brevicompactum and Synthetic Analogues

γ-Lactone-functionalized antitumoral acetogenins are the most potent inhibitors of Mitochondrial Complex I

Jatrophane Diterpenes from the Latex of Euphorbia obtusifolia with Inhibitory Activity on the Mammalian Mitochondrial Respiratory Chain

Cherimolin-1, New Selective Inhibitor of the First Energy-Coupling Site of the NADH:Ubiquinone Oxidoreductase (Complex I)

Bisbenzyltetrahydroisoquinolines, a new class of inhibitors of the mitochondrial respiratory chain complex I

Effects of vitamin A deficiency on mitochondrial function in rat liver and heart

Enantiospecific Semisynthesis of (+)-Almuheptolide-A, a Novel Natural Heptolide Inhibitor of the Mammalian Mitochondrial Respiratory Chain

Complex I and Complex III of Mitochondria Have Common Inhibitors Acting as Ubiquinone Antagonists

Rollimembrin, a novel acetogenin inhibitor of mammalian mitochondrial complex I

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