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Structure-Based Approach for the Discovery of Bis-benzamidines as Novel Inhibitors of Matriptase

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1349-1355

2001

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Of mice and Myc: c-Myc and mammary tumorigenesis

Journal of mammary gland biology and neoplasia, 2004-01, Vol.9 (1), p.27-37

2004

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Co-expression of matriptase and N-acetylglucosaminyltransferase V in thyroid cancer tissues--its possible role in prolonged stability in vivo by aberrant glycosylation

Glycobiology (Oxford), 2006-05, Vol.16 (5), p.368-374

2006

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Activation of Hepatocyte Growth Factor and Urokinase/Plasminogen Activator by Matriptase, an Epithelial Membrane Serine Protease

The Journal of biological chemistry, 2000-11, Vol.275 (47), p.36720-36725

2000

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Production of soluble matriptase by human cancer cell lines and cell surface activation of its zymogen by trypsin

Journal of cellular biochemistry, 2005-06, Vol.95 (3), p.632-647

2005

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Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer

Cancer research (Chicago, Ill.), 2003-03, Vol.63 (5), p.1101-1105

2003

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Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts

American Journal of Physiology: Cell Physiology, 2004-05, Vol.286 (5), p.C1159-C1169

2004

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Calmodulin modulates Akt activity in human breast cancer cell lines

Breast cancer research and treatment, 2009-06, Vol.115 (3), p.545-560

2009

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Purification and Characterization of a Complex Containing Matriptase and a Kunitz-type Serine Protease Inhibitor from Human Milk

The Journal of biological chemistry, 1999-06, Vol.274 (26), p.18237-18242

1999

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Expression of the serine protease Matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: Correlation with clinical outcome and tumor clinicopathological parameters

Clinical cancer research, 2002-04, Vol.8 (4), p.1101-1107

2002

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Zymogen activation, inhibition, and ectodomain shedding of matriptase

Frontiers in bioscience, 2008-01, Vol.13, p.621

2008

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Design and Synthesis of Novel and Potent Inhibitors of the Type II Transmembrane Serine Protease, Matriptase, Based upon the Sunflower Trypsin Inhibitor-1

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.5976-5983

2007

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Molecular Cloning of cDNA for Matriptase, a Matrix-degrading Serine Protease with Trypsin-like Activity

The Journal of biological chemistry, 1999-06, Vol.274 (26), p.18231-18236

1999

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Overexpression of c-Myc Alters G1/S Arrest following Ionizing Radiation

Molecular and Cellular Biology, 2002-03, Vol.22 (6), p.1819-1833

2002

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Design and Synthesis of Redox Stable Analogues of Sunflower Trypsin Inhibitors (SFTI-1) on Solid Support, Potent Inhibitors of Matriptase

Organic letters, 2007-01, Vol.9 (1), p.9-12

2007

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Matrix metalloproteinase inhibitors

Investigational new drugs, 1997-01, Vol.15 (1), p.61-75

1997

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Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells

American Journal of Physiology: Cell Physiology, 2006-07, Vol.291 (1), p.C40-C49

2006

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Multicolour spectral karyotyping of mouse chromosomes

Nature genetics, 1996-11, Vol.14 (3), p.312-315

1996

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Increased expression of matriptase is associated with histopathologic grades of cervical neoplasia

Human pathology, 2005-06, Vol.36 (6), p.626-633

2005

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Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation

American Journal of Physiology: Cell Physiology, 2008-08, Vol.295 (2), p.C365-C377

2008

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Estrogen-Induced Factors of Breast Cancer Cells Partially Replace Estrogen to Promote Tumor Growth

Science (American Association for the Advancement of Science), 1986-06, Vol.232 (4757), p.1540-1543

1986

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Roles of the matrix metalloproteinases in mammary gland development and cancer

Breast cancer research and treatment, 1998-07, Vol.50 (2), p.97-116

1998

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Cell Death in MMTV-c-myc Transgenic Mouse Mammary Tumors May Not Be Typical Apoptosis

Laboratory investigation, 2003-10, Vol.83 (10), p.1437-1449

2003

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Deregulated activation of matriptase in breast cancer cells

Clinical & experimental metastasis, 2002-01, Vol.19 (7), p.639-649

2002

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EXPLANT-CELL CULTURE OF PRIMARY MAMMARY TUMORS FROM MMTV-c-Myc TRANSGENIC MICE

In vitro cellular & developmental biology. Animal, 2004-01, Vol.40 (1), p.14-21

2004

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Structure-Based Approach for the Discovery of Bis-benzamidines as Novel Inhibitors of Matriptase

Of mice and Myc: c-Myc and mammary tumorigenesis

Co-expression of matriptase and N-acetylglucosaminyltransferase V in thyroid cancer tissues--its possible role in prolonged stability in vivo by aberrant glycosylation

Activation of Hepatocyte Growth Factor and Urokinase/Plasminogen Activator by Matriptase, an Epithelial Membrane Serine Protease

Production of soluble matriptase by human cancer cell lines and cell surface activation of its zymogen by trypsin

Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer

Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts

Calmodulin modulates Akt activity in human breast cancer cell lines

Purification and Characterization of a Complex Containing Matriptase and a Kunitz-type Serine Protease Inhibitor from Human Milk

Expression of the serine protease Matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: Correlation with clinical outcome and tumor clinicopathological parameters

Zymogen activation, inhibition, and ectodomain shedding of matriptase

Design and Synthesis of Novel and Potent Inhibitors of the Type II Transmembrane Serine Protease, Matriptase, Based upon the Sunflower Trypsin Inhibitor-1

Molecular Cloning of cDNA for Matriptase, a Matrix-degrading Serine Protease with Trypsin-like Activity

Overexpression of c-Myc Alters G1/S Arrest following Ionizing Radiation

Design and Synthesis of Redox Stable Analogues of Sunflower Trypsin Inhibitors (SFTI-1) on Solid Support, Potent Inhibitors of Matriptase

Matrix metalloproteinase inhibitors

Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells

Multicolour spectral karyotyping of mouse chromosomes

Increased expression of matriptase is associated with histopathologic grades of cervical neoplasia

Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation

Estrogen-Induced Factors of Breast Cancer Cells Partially Replace Estrogen to Promote Tumor Growth

Roles of the matrix metalloproteinases in mammary gland development and cancer

Cell Death in MMTV-c-myc Transgenic Mouse Mammary Tumors May Not Be Typical Apoptosis

Deregulated activation of matriptase in breast cancer cells

EXPLANT-CELL CULTURE OF PRIMARY MAMMARY TUMORS FROM MMTV-c-Myc TRANSGENIC MICE

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