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Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer

Cancer research (Chicago, Ill.), 2021-03, Vol.81 (6), p.1583-1594

2021

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Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

Cell reports (Cambridge), 2020-05, Vol.31 (8), p.107669-107669, Article 107669

2020

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A PDX/Organoid Biobank of Advanced Prostate Cancers Captures Genomic and Phenotypic Heterogeneity for Disease Modeling and Therapeutic Screening

Clinical cancer research, 2018-09, Vol.24 (17), p.4332-4345

2018

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Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

Cancer research (Chicago, Ill.), 2014-04, Vol.74 (8), p.2270-2282

2014

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Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer

Nature genetics, 2020-10, Vol.52 (10), p.1011-1017

2020

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LuCaP Prostate Cancer Patient‐Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease and Serve as Models for Evaluating Cancer Therapeutics

The Prostate, 2017-05, Vol.77 (6), p.654-671

2017

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The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis

Cancer discovery, 2014-11, Vol.4 (11), p.1310-1325

2014

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A positive role of c-Myc in regulating androgen receptor and its splice variants in prostate cancer

Oncogene, 2019-06, Vol.38 (25), p.4977-4989

2019

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Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (19), p.E4473-E4482

2018

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Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer

Nature communications, 2014-09, Vol.5 (1), p.4988-4988, Article 4988

2014

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Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer

Nature communications, 2021-07, Vol.12 (1), p.4217-4217, Article 4217

2021

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Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models

Clinical cancer research, 2017-08, Vol.23 (15), p.4335-4346

2017

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Radium-223 mechanism of action: implications for use in treatment combinations

Nature reviews. Urology, 2019-12, Vol.16 (12), p.745-756

2019

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SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Clinical cancer research, 2015-10, Vol.21 (20), p.4698-4708

2015

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Targeted therapy for advanced prostate cancer: inhibition of the PI3K/Akt/mTOR pathway

Current cancer drug targets, 2009-03, Vol.9 (2), p.237-249

2009

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Increased transcription and high translation efficiency lead to accumulation of androgen receptor splice variant after androgen deprivation therapy

Cancer letters, 2021-04, Vol.504, p.37-48

2021

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Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer

Clinical cancer research, 2019-01, Vol.25 (1), p.426-439

2019

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Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (41), p.17087-17092

2011

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Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells

Cancer biology & therapy, 2022-12, Vol.23 (1), p.173-185

2022

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Downregulation of Dipeptidyl Peptidase 4 Accelerates Progression to Castration-Resistant Prostate Cancer

Cancer research (Chicago, Ill.), 2018-11, Vol.78 (22), p.6354-6362

2018

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Proteomic and Transcriptomic Profiling Reveals Mitochondrial Oxidative Phosphorylation as Therapeutic Vulnerability in Androgen Receptor Pathway Active Prostate Tumors

Cancers, 2022-03, Vol.14 (7), p.1739

2022

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MCM2-7 complex is a novel druggable target for neuroendocrine prostate cancer

Scientific reports, 2021-06, Vol.11 (1), p.13305-13305, Article 13305

2021

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Oxidation of p-[125I]Iodobenzoic Acid and p-[211At]Astatobenzoic Acid Derivatives and Evaluation In Vivo

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10655

2022

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Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth

The Journal of clinical investigation, 2023-08, Vol.133 (15)

2023

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Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer

Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

A PDX/Organoid Biobank of Advanced Prostate Cancers Captures Genomic and Phenotypic Heterogeneity for Disease Modeling and Therapeutic Screening

Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer

LuCaP Prostate Cancer Patient‐Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease and Serve as Models for Evaluating Cancer Therapeutics

The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis

A positive role of c-Myc in regulating androgen receptor and its splice variants in prostate cancer

Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer

Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer

Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer

Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models

Radium-223 mechanism of action: implications for use in treatment combinations

SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Targeted therapy for advanced prostate cancer: inhibition of the PI3K/Akt/mTOR pathway

Increased transcription and high translation efficiency lead to accumulation of androgen receptor splice variant after androgen deprivation therapy

Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer

Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells

Downregulation of Dipeptidyl Peptidase 4 Accelerates Progression to Castration-Resistant Prostate Cancer

Proteomic and Transcriptomic Profiling Reveals Mitochondrial Oxidative Phosphorylation as Therapeutic Vulnerability in Androgen Receptor Pathway Active Prostate Tumors

MCM2-7 complex is a novel druggable target for neuroendocrine prostate cancer

Oxidation of p-[125I]Iodobenzoic Acid and p-[211At]Astatobenzoic Acid Derivatives and Evaluation In Vivo

Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer

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