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Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans

European journal of clinical pharmacology, 2022-06, Vol.78 (6), p.975-987

2022

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Microdosed Cocktail of Three Oral Factor Xa Inhibitors to Evaluate Drug–Drug Interactions with Potential Perpetrator Drugs

Clinical pharmacokinetics, 2019-09, Vol.58 (9), p.1155-1163

2019

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A Nanocarrier Approach for Oral Peptide Delivery: Evaluation of Cell‐Penetrating‐Peptide‐Modified Liposomal Formulations in Dogs

Advanced therapeutics, 2023-10, Vol.6 (10)

2023

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Clinical feasibility of dried blood spots: Analytics, validation, and applications

Journal of pharmaceutical and biomedical analysis, 2016-10, Vol.130, p.231-243

2016

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Treatment with rilpivirine does not alter plasma concentrations of the CYP3A substrates tadalafil and midazolam in humans

Journal of antimicrobial chemotherapy, 2016-08, Vol.71 (8), p.2241-2247

2016

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The Effect of Induction of CYP3A4 by St John's Wort on Ambrisentan Plasma Pharmacokinetics in Volunteers of known CYP2C19 Genotype

Basic & clinical pharmacology & toxicology, 2015-05, Vol.116 (5), p.423-428

2015

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Pre‐systemic Elimination of Tilidine: Localization and Consequences for the Formation of the Active Metabolite Nortilidine

Basic & clinical pharmacology & toxicology, 2015-02, Vol.116 (2), p.129-133

2015

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Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity

Journal of clinical pharmacology, 2013-11, Vol.53 (11), p.1199-1204

2013

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Bortezomib, carfilzomib and ixazomib do not mediate relevant transporter-based drug-drug interactions

Oncology letters, 2017-09, Vol.14 (3), p.3185-3192

2017

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IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

Cell, 2020-09, Vol.182 (5), p.1252-1270.e34

2020

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Electrospray tandem mass spectroscopic characterisation of 18 antiretroviral drugs and simultaneous quantification of 12 antiretrovirals in plasma

Rapid communications in mass spectrometry, 2007-08, Vol.21 (16), p.2704-2716

2007

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Desorption/Ionization-MS Methods for Drug Quantification in Biological Matrices and Their Validation Following Regulatory Guidance

Analytical chemistry (Washington), 2021-05, Vol.93 (19), p.7152-7163

2021

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Dried-Blood-Spot Technique to Monitor Direct Oral Anticoagulants: Clinical Validation of a UPLC–MS/MS-Based Assay

Analytical chemistry (Washington), 2018-08, Vol.90 (15), p.9395-9402

2018

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Turquoise to dark green organs at autopsy

Virchows Archiv : an international journal of pathology, 2009-03, Vol.454 (3), p.341-344

2009

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Rapid and Sensitive Drug Quantification in Tissue Sections Using Matrix Assisted Laser Desorption Ionization-Ion Mobility-Mass Spectrometry Profiling

Journal of the American Society for Mass Spectrometry, 2020-03, Vol.31 (3), p.742-751

2020

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Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients

PloS one, 2011-12, Vol.6 (12), p.e27810

2011

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Voriconazole Concentration in Human Aqueous Humor and Plasma during Topical or Combined Topical and Systemic Administration for Fungal Keratitis

Antimicrobial Agents and Chemotherapy, 2007-01, Vol.51 (1), p.239-244

2007

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Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1′-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry

Analytical and bioanalytical chemistry, 2012-03, Vol.402 (7), p.2439-2450

2012

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Clomethiazole inhibits cytochrome P450 2E1 and improves alcoholic liver disease

Gut, 2022-04, Vol.71 (4), p.842

2022

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Intact plasma quantification of the large therapeutic lipopeptide bulevirtide

Analytical and bioanalytical chemistry, 2021-09, Vol.413 (22), p.5645-5654

2021

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Dose-Dependent Bioavailability and CYP3A Inhibition Contribute to Non-Linear Pharmacokinetics of Voriconazole

Clinical pharmacokinetics, 2016-12, Vol.55 (12), p.1535-1545

2016

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Substantially increased sildenafil bioavailability after sublingual administration in children with congenital heart disease: two case reports

Journal of medical case reports, 2014-05, Vol.8 (1), p.171-171, Article 171

2014

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Pharmacoenhancement of Low Crizotinib Plasma Concentrations in Patients with Anaplastic Lymphoma Kinase‐Positive Non‐Small Cell Lung Cancer using the CYP3A Inhibitor Cobicistat

Clinical and translational science, 2021-03, Vol.14 (2), p.487-491

2021

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Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion

Clinical pharmacokinetics, 2022-11, Vol.61 (11), p.1595-1607

2022

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Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans

Microdosed Cocktail of Three Oral Factor Xa Inhibitors to Evaluate Drug–Drug Interactions with Potential Perpetrator Drugs

A Nanocarrier Approach for Oral Peptide Delivery: Evaluation of Cell‐Penetrating‐Peptide‐Modified Liposomal Formulations in Dogs

Clinical feasibility of dried blood spots: Analytics, validation, and applications

Treatment with rilpivirine does not alter plasma concentrations of the CYP3A substrates tadalafil and midazolam in humans

The Effect of Induction of CYP3A4 by St John's Wort on Ambrisentan Plasma Pharmacokinetics in Volunteers of known CYP2C19 Genotype

Pre‐systemic Elimination of Tilidine: Localization and Consequences for the Formation of the Active Metabolite Nortilidine

Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity

Bortezomib, carfilzomib and ixazomib do not mediate relevant transporter-based drug-drug interactions

IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

Electrospray tandem mass spectroscopic characterisation of 18 antiretroviral drugs and simultaneous quantification of 12 antiretrovirals in plasma

Desorption/Ionization-MS Methods for Drug Quantification in Biological Matrices and Their Validation Following Regulatory Guidance

Dried-Blood-Spot Technique to Monitor Direct Oral Anticoagulants: Clinical Validation of a UPLC–MS/MS-Based Assay

Turquoise to dark green organs at autopsy

Rapid and Sensitive Drug Quantification in Tissue Sections Using Matrix Assisted Laser Desorption Ionization-Ion Mobility-Mass Spectrometry Profiling

Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients

Voriconazole Concentration in Human Aqueous Humor and Plasma during Topical or Combined Topical and Systemic Administration for Fungal Keratitis

Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1′-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry

Clomethiazole inhibits cytochrome P450 2E1 and improves alcoholic liver disease

Intact plasma quantification of the large therapeutic lipopeptide bulevirtide

Dose-Dependent Bioavailability and CYP3A Inhibition Contribute to Non-Linear Pharmacokinetics of Voriconazole

Substantially increased sildenafil bioavailability after sublingual administration in children with congenital heart disease: two case reports

Pharmacoenhancement of Low Crizotinib Plasma Concentrations in Patients with Anaplastic Lymphoma Kinase‐Positive Non‐Small Cell Lung Cancer using the CYP3A Inhibitor Cobicistat

Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion

A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy

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