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Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation

Chemistry & biodiversity, 2021-05, Vol.18 (5), p.e2001037-n/a

2021

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A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation

Scientific reports, 2022-09, Vol.12 (1), p.15139-15139, Article 15139

2022

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Human Hepatocellular Carcinoma Classification from H&E Stained Histopathology Images with 3D Convolutional Neural Networks and Focal Loss Function

Journal of imaging, 2023-01, Vol.9 (2), p.25

2023

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Object‐Oriented Segmentation of Cell Nuclei in Fluorescence Microscopy Images

Cytometry. Part A, 2018-10, Vol.93 (10), p.1019-1028

2018

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Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines

BMC chemistry, 2021-12, Vol.15 (1), p.66-66, Article 66

2021

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Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases

Briefings in bioinformatics, 2019-09, Vol.20 (5), p.1878-1912

2019

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A visual object tracking benchmark for cell motility in time-lapse imaging

Signal, image and video processing, 2019-09, Vol.13 (6), p.1063-1070

2019

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Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells

BMC cancer, 2022-03, Vol.22 (1), p.320-320, Article 320

2022

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Intermittent Hypoxia Attenuates and Reverses Epinephrine‐Induced Changes in Gene Expression in Endothelial Cells

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Development of a novel zebrafish xenograft model in ache mutants using liver cancer cell lines

Scientific reports, 2018-01, Vol.8 (1), p.1570-14, Article 1570

2018

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Design, Synthesis and In Vitro Cytotoxic Activity of New 6,9-Disubstituted Purine Analogues

Acta chimica Slovenica, 2020-03, Vol.67 (1), p.70-82

2020

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Contrast Enhancement of Microscopy Images Using Image Phase Information

IEEE access, 2018-01, Vol.6, p.3839-3850

2018

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Design, synthesis, and biological evaluation of indole-based 1,4-disubstituted piperazines as cytotoxic agents

Turkish journal of chemistry, 2012-01

2012

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DEEPScreen: high performance drug-target interaction prediction with convolutional neural networks using 2-D structural compound representations

Chemical science (Cambridge), 2020-03, Vol.11 (9), p.2531-2557

2020

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Abstract LB-A08: Differential alteration of IL-8 in response to Sorafenib and PI3K/Akt/mTOR inhibitors in liver cancer cells and in liver cancer stem cells

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.LB-A08-LB-A08

2018

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Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

European journal of medicinal chemistry, 2021-10, Vol.221, p.113489-113489, Article 113489

2021

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Bioactivity-guided isolation of cytotoxic secondary metabolites from the roots of Glycyrrhiza glabra and elucidation of their mechanisms of action

Industrial crops and products, 2018-11, Vol.124, p.389-396

2018

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Novel indole-pyrazole hybrids as potential tubulin-targeting agents; Synthesis, antiproliferative evaluation, and molecular modeling studies

Journal of molecular structure, 2023-08, Vol.1285, p.135477, Article 135477

2023

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Design and synthesis of novel substituted indole-acrylamide derivatives and evaluation of their anti-cancer activity as potential tubulin-targeting agents

Journal of molecular structure, 2022-04, Vol.1254, p.132345, Article 132345

2022

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Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.1352-1361

2018

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iBioProVis: interactive visualization and analysis of compound bioactivity space

Bioinformatics, 2020-11, Vol.36 (17), p.4674-4674

2020

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Abstract 5235: In vitro validation of drug-target interactions revealed in silico by Comprehensive Resource of Biomedical Relations with Network Representations and Deep Learning (CROssBAR) in HCC

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5235-5235

2020

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Abstract 3937: Differential alteration of IL-8 in liver cancer stem cell enrichment in response to PI3K/Akt/mTOR inhibitors and sorafenib

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3937-3937

2018

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DeepDistance: A multi-task deep regression model for cell detection in inverted microscopy images

Medical image analysis, 2020-07, Vol.63, p.101720-101720, Article 101720

2020

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Human Hepatocellular Carcinoma Classification from H E Stained Histopathology Images with 3D Convolutional Neural Networks and Focal Loss Function

Journal of imaging, 2023-01, Vol.9 (2), p.25

2023

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Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation

A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation

Human Hepatocellular Carcinoma Classification from H&E Stained Histopathology Images with 3D Convolutional Neural Networks and Focal Loss Function

Object‐Oriented Segmentation of Cell Nuclei in Fluorescence Microscopy Images

Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines

Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases

A visual object tracking benchmark for cell motility in time-lapse imaging

Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells

Intermittent Hypoxia Attenuates and Reverses Epinephrine‐Induced Changes in Gene Expression in Endothelial Cells

Development of a novel zebrafish xenograft model in ache mutants using liver cancer cell lines

Design, Synthesis and In Vitro Cytotoxic Activity of New 6,9-Disubstituted Purine Analogues

Contrast Enhancement of Microscopy Images Using Image Phase Information

Design, synthesis, and biological evaluation of indole-based 1,4-disubstituted piperazines as cytotoxic agents

DEEPScreen: high performance drug-target interaction prediction with convolutional neural networks using 2-D structural compound representations

Abstract LB-A08: Differential alteration of IL-8 in response to Sorafenib and PI3K/Akt/mTOR inhibitors in liver cancer cells and in liver cancer stem cells

Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

Bioactivity-guided isolation of cytotoxic secondary metabolites from the roots of Glycyrrhiza glabra and elucidation of their mechanisms of action

Novel indole-pyrazole hybrids as potential tubulin-targeting agents; Synthesis, antiproliferative evaluation, and molecular modeling studies

Design and synthesis of novel substituted indole-acrylamide derivatives and evaluation of their anti-cancer activity as potential tubulin-targeting agents

Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

iBioProVis: interactive visualization and analysis of compound bioactivity space

Abstract 5235: In vitro validation of drug-target interactions revealed in silico by Comprehensive Resource of Biomedical Relations with Network Representations and Deep Learning (CROssBAR) in HCC

Abstract 3937: Differential alteration of IL-8 in liver cancer stem cell enrichment in response to PI3K/Akt/mTOR inhibitors and sorafenib

DeepDistance: A multi-task deep regression model for cell detection in inverted microscopy images

Human Hepatocellular Carcinoma Classification from H E Stained Histopathology Images with 3D Convolutional Neural Networks and Focal Loss Function

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