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Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment

Nucleic acid therapeutics, 2019-02, Vol.29 (1), p.1

2019

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Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment

Molecular therapy. Nucleic acids, 2012-08, Vol.1 (8), p.e38-e38, Article e38

2012

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Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo

Organic & biomolecular chemistry, 2013-11, Vol.11 (43), p.7621-7630

2013

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Systematic screening of LNA/2′- O-methyl chimeric derivatives of a TAR RNA aptamer

FEBS letters, 2007-02, Vol.581 (4), p.771-774

2007

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PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation

Nucleic acids research, 2011-07, Vol.39 (12), p.5284

2011

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Cell penetrating peptide conjugates of steric block oligonucleotides

Advanced drug delivery reviews, 2008-03, Vol.60 (4), p.517-529

2008

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Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells

Nucleic acids research, 2005-01, Vol.33 (21), p.6837

2005

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RNA targeting with peptide conjugates of oligonucleotides, siRNA and PNA

Blood cells, molecules, & diseases, 2007, Vol.38 (1), p.1-7

2007

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Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides

Nucleic acids research, 2005-01, Vol.33 (1), p.27

2005

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Parallel synthesis of cell-penetrating peptide conjugates of PMO toward exon skipping enhancement in Duchenne muscular dystrophy

Nucleic acid therapeutics, 2015-02, Vol.25 (1), p.1

2015

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A Peptide-Based Dendrimer That Enhances the Splice-Redirecting Activity of PNA Conjugates in Cells

Bioconjugate chemistry, 2009-08, Vol.20 (8), p.1523-1530

2009

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Peptide nanoparticle delivery of charge-neutral splice-switching morpholino oligonucleotides

Nucleic acid therapeutics, 2015-04, Vol.25 (2), p.65

2015

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Peptide-based delivery of steric-block PNA oligonucleotides

Methods in molecular biology (Clifton, N.J.), 2009, Vol.480, p.85

2009

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Targeting the HIV-1 RNA leader sequence with synthetic oligonucleotides and siRNA: Chemistry and cell delivery

Biochimica et biophysica acta, 2006-03, Vol.1758 (3), p.290-300

2006

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Synthesis of Peptide−Oligonucleotide Conjugates with Single and Multiple Peptides Attached to 2‘-Aldehydes through Thiazolidine, Oxime, and Hydrazine Linkages

Bioconjugate chemistry, 2002-07, Vol.13 (4), p.822-830

2002

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Enhanced splice correction by 3′, 5′-serinol and 2′-(ω-O-methylserinol) guarded OMe-RNA/DNA mixmers in cells

Artificial DNA, PNA & XNA, 2013-07, Vol.4 (3), p.77-83

2013

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Steric inhibition of human immunodeficiency virus type-1 Tat-dependent trans-activation in vitro and in cells by oligonucleotides containing 2'-O-methyl G-clamp ribonucleoside analogues

Nucleic acids research, 2003-06, Vol.31 (11), p.2759

2003

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A bi-functional siRNA construct induces RNA interference and also primes PCR amplification for its own quantification

Nucleic acids research, 2005-01, Vol.33 (18), p.e151

2005

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Overview of alternative oligonucleotide chemistries for exon skipping

Methods in molecular biology (Clifton, N.J.), 2012, Vol.867, p.365

2012

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Anti-HIV Activity of Steric Block Oligonucleotides

Annals of the New York Academy of Sciences, 2006-10, Vol.1082 (1), p.103-115

2006

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Splice redirection as a convenient assay to monitor CPP-ON efficiency and mechanism

Methods in molecular biology (Clifton, N.J.), 2011, Vol.683, p.307

2011

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PNA-peptide conjugates as intracellular gene control agents

Nucleic Acids Symposium Series, 2008, Vol.52 (1), p.31-32

2008

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ANTIVIRAL ACTIVITY OF STERIC-BLOCK OLIGONUCLEOTIDES TARGETING THE HIV-1 TRANS-ACTIVATION RESPONSE AND PACKAGING SIGNAL STEM-LOOP RNAS

Nucleosides, nucleotides & nucleic acids, 2005-01, Vol.24 (5-7), p.393-396

2005

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Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargoElectronic supplementary information (ESI) available: MALDI mass-spectroscopy data for peptides and PNA705 conjugates of LB1 and LB2. Amino acid sequences, purity, synthesis and conjugation yields of LB2. Examples of HPLC-graphs and MALDI mass-spectra for peptides and conjugates. Luciferase readout of LB1 crude and purified PNA705 conjugates and single data-point splice correction a

2013-10

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Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo† †Electronic supplementary information (ESI) available: MALDI mass-spectroscopy data for peptides and PNA705 conjugates of LB1 and LB2. Amino acid sequences, purity, synthesis and conjugation yields of LB2. Examples of HPLC-graphs and MALDI mass-spectra for peptides and conjugates. Luciferase readout of LB1 crude and purified PNA705 conjugates and single data-point splice correctio

Organic & biomolecular chemistry, 2013-10, Vol.11 (43), p.7621-7630

2013

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Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment

Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment

Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo

Systematic screening of LNA/2′- O-methyl chimeric derivatives of a TAR RNA aptamer

PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation

Cell penetrating peptide conjugates of steric block oligonucleotides

Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells

RNA targeting with peptide conjugates of oligonucleotides, siRNA and PNA

Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides

Parallel synthesis of cell-penetrating peptide conjugates of PMO toward exon skipping enhancement in Duchenne muscular dystrophy

A Peptide-Based Dendrimer That Enhances the Splice-Redirecting Activity of PNA Conjugates in Cells

Peptide nanoparticle delivery of charge-neutral splice-switching morpholino oligonucleotides

Peptide-based delivery of steric-block PNA oligonucleotides

Targeting the HIV-1 RNA leader sequence with synthetic oligonucleotides and siRNA: Chemistry and cell delivery

Synthesis of Peptide−Oligonucleotide Conjugates with Single and Multiple Peptides Attached to 2‘-Aldehydes through Thiazolidine, Oxime, and Hydrazine Linkages

Enhanced splice correction by 3′, 5′-serinol and 2′-(ω-O-methylserinol) guarded OMe-RNA/DNA mixmers in cells

Steric inhibition of human immunodeficiency virus type-1 Tat-dependent trans-activation in vitro and in cells by oligonucleotides containing 2'-O-methyl G-clamp ribonucleoside analogues

A bi-functional siRNA construct induces RNA interference and also primes PCR amplification for its own quantification

Overview of alternative oligonucleotide chemistries for exon skipping

Anti-HIV Activity of Steric Block Oligonucleotides

Splice redirection as a convenient assay to monitor CPP-ON efficiency and mechanism

PNA-peptide conjugates as intracellular gene control agents

ANTIVIRAL ACTIVITY OF STERIC-BLOCK OLIGONUCLEOTIDES TARGETING THE HIV-1 TRANS-ACTIVATION RESPONSE AND PACKAGING SIGNAL STEM-LOOP RNAS

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