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Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

The lancet oncology, 2015-12, Vol.16 (16), p.1639-1650

2015

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update

Clinical pharmacology and therapeutics, 2018-02, Vol.103 (2), p.210-216

2018

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Recommendations for HLA‐B15:02 and HLA‐A31:01 genetic testing to reduce the risk of carbamazepine‐induced hypersensitivity reactions

Epilepsia (Copenhagen), 2014-04, Vol.55 (4), p.496-506

2014

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Recommendations for genetic testing to reduce the incidence of anthracycline‐induced cardiotoxicity

British journal of clinical pharmacology, 2016-09, Vol.82 (3), p.683-695

2016

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Clinical importance of risk variants in the dihydropyrimidine dehydrogenase gene for the prediction of early‐onset fluoropyrimidine toxicity

International journal of cancer, 2015-02, Vol.136 (3), p.730-739

2015

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Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity

Pharmacogenomics, 2011-09, Vol.12 (9), p.1321

2011

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A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer

Nature genetics, 2015-09, Vol.47 (9), p.1079-1084

2015

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Alterations in homologous recombination repair genes in prostate cancer brain metastases

Nature communications, 2022-05, Vol.13 (1), p.2400-2400, Article 2400

2022

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Comparison of methods for donor-derived cell-free DNA quantification in plasma and urine from solid organ transplant recipients

Frontiers in genetics, 2023-01, Vol.14, p.1089830-1089830

2023

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Tacrolimus monitoring in hair samples of kidney transplant recipients

Frontiers in medicine, 2023-12, Vol.10, p.1307505-1307505

2023

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VKORC1 and CYP2C9 genotypes are predictors of warfarin-related outcomes in children

Pediatric blood & cancer, 2014-06, Vol.61 (6), p.1055-1062

2014

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LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients

Biomedical chromatography, 2013-01, Vol.27 (1), p.7-16

2013

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Investigation of Different Library Preparation and Tissue of Origin Deconvolution Methods for Urine and Plasma cfDNA Methylome Analysis

Diagnostics (Basel), 2023-07, Vol.13 (15), p.2505

2023

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Accuracy of a Single, Heparin-Calibrated Anti-Xa Assay for the Measurement of Rivaroxaban, Apixaban, and Edoxaban Drug Concentrations: A Prospective Cross-Sectional Study

Frontiers in cardiovascular medicine, 2022-03, Vol.9, p.817826-817826

2022

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High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis

Frontiers in genetics, 2020-08, Vol.11, p.951-951

2020

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Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations

Genes, 2020-11, Vol.11 (11), p.1

2020

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A Novel Nomenclature for Repeat Motifs in the Thymidylate Synthase Enhancer Region and Its Relevance for Pharmacogenetic Studies

Journal of personalized medicine, 2020-10, Vol.10 (4), p.181

2020

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Hypermethylation of the DPYD promoter region is not a major predictor of severe toxicity in 5-fluorouracil based chemotherapy

Journal of experimental & clinical cancer research, 2008-10, Vol.27 (1), p.54-54, Article 54

2008

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Challenges in the introduction of next-generation sequencing (NGS) for diagnostics of myeloid malignancies into clinical routine use

Blood cancer journal (New York), 2018-11, Vol.8 (11), p.113-10, Article 113

2018

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HLA-A31:01 and HLA-B15:02 as Genetic Markers for Carbamazepine Hypersensitivity in Children

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.142-149

2013

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Genotype-guided fluoropyrimidine dosing: ready for implementation

The lancet oncology, 2018-11, Vol.19 (11), p.1421-1422

2018

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Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5‐fluorouracil toxicity

British journal of clinical pharmacology, 2021-08, Vol.87 (8), p.3234-3243

2021

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Assessment of hair cortisol as a potential biomarker for possible adrenal suppression due to inhaled corticosteroid use in children with asthma: A retrospective observational study

Clinical biochemistry, 2018-06, Vol.56, p.26-32

2018

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DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (8), p.1203-1213

2023

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Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update

Recommendations for HLA‐B15:02 and HLA‐A31:01 genetic testing to reduce the risk of carbamazepine‐induced hypersensitivity reactions

Recommendations for genetic testing to reduce the incidence of anthracycline‐induced cardiotoxicity

Clinical importance of risk variants in the dihydropyrimidine dehydrogenase gene for the prediction of early‐onset fluoropyrimidine toxicity

Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity

A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer

Alterations in homologous recombination repair genes in prostate cancer brain metastases

Comparison of methods for donor-derived cell-free DNA quantification in plasma and urine from solid organ transplant recipients

Tacrolimus monitoring in hair samples of kidney transplant recipients

VKORC1 and CYP2C9 genotypes are predictors of warfarin-related outcomes in children

LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients

Investigation of Different Library Preparation and Tissue of Origin Deconvolution Methods for Urine and Plasma cfDNA Methylome Analysis

Accuracy of a Single, Heparin-Calibrated Anti-Xa Assay for the Measurement of Rivaroxaban, Apixaban, and Edoxaban Drug Concentrations: A Prospective Cross-Sectional Study

High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis

Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations

A Novel Nomenclature for Repeat Motifs in the Thymidylate Synthase Enhancer Region and Its Relevance for Pharmacogenetic Studies

Hypermethylation of the DPYD promoter region is not a major predictor of severe toxicity in 5-fluorouracil based chemotherapy

Challenges in the introduction of next-generation sequencing (NGS) for diagnostics of myeloid malignancies into clinical routine use

HLA-A31:01 and HLA-B15:02 as Genetic Markers for Carbamazepine Hypersensitivity in Children

Genotype-guided fluoropyrimidine dosing: ready for implementation

Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5‐fluorouracil toxicity

Assessment of hair cortisol as a potential biomarker for possible adrenal suppression due to inhaled corticosteroid use in children with asthma: A retrospective observational study

DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations

Pharmacogenomics of Vincristine‐Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy Genes

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