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Bone marrow lesions in osteoarthritis: What lies beneath

Journal of orthopaedic research, 2018-07, Vol.36 (7), p.1818-1825

2018

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Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistance

Journal of bone and mineral research, 2012-09, Vol.27 (9), p.1936-1950

2012

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Age-related changes in the plasticity and toughness of human cortical bone at multiple length scales

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (35), p.14416-14421

2011

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Contributions of Material Properties and Structure to Increased Bone Fragility for a Given Bone Mass in the UCD‐T2DM Rat Model of Type 2 Diabetes

Journal of bone and mineral research, 2018-06, Vol.33 (6), p.1066-1075

2018

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Characterization of the effects of x-ray irradiation on the hierarchical structure and mechanical properties of human cortical bone

Biomaterials, 2011-12, Vol.32 (34), p.8892-8904

2011

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How Tough Is Brittle Bone? Investigating Osteogenesis Imperfecta in Mouse Bone

Journal of bone and mineral research, 2014-06, Vol.29 (6), p.1392-1401

2014

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Osteocyte Control of Bone Quality and Fragility in Skeletal Aging

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

Alliston, Tamara

2022

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Osteocyte-Intrinsic TGF-β Signaling Regulates Bone Quality through Perilacunar/Canalicular Remodeling

Cell reports (Cambridge), 2017-11, Vol.21 (9), p.2585-2596

2017

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Load regulates bone formation and Sclerostin expression through a TGFβ-dependent mechanism

PloS one, 2013, Vol.8 (1), p.e53813-e53813

2013

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Smad3 binds scleraxis and mohawk and regulates tendon matrix organization

Journal of orthopaedic research, 2013-09, Vol.31 (9), p.1475-1483

2013

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Deep coverage and quantification of the bone proteome provides enhanced opportunities for new discoveries in skeletal biology and disease

PloS one, 2023-10, Vol.18 (10), p.e0292268-e0292268

2023

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Biologically Regulated Marrow Stimulation by Blocking TGF-β1 With Losartan Oral Administration Results in Hyaline-like Cartilage Repair: A Rabbit Osteochondral Defect Model

The American journal of sports medicine, 2020-03, Vol.48 (4), p.974-984

2020

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Biological Regulation of Bone Quality

Current osteoporosis reports, 2014-09, Vol.12 (3), p.366-375

Alliston, Tamara

2014

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Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis

Bone research, 2019-11, Vol.7, p.34-17

2019

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Effects of cell type and configuration on anabolic and catabolic activity in 3D co‐culture of mesenchymal stem cells and nucleus pulposus cells

Journal of orthopaedic research, 2017-01, Vol.35 (1), p.61-73

2017

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Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension

eLife, 2015-12, Vol.4, p.e09300-e09300

2015

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Bone-cartilage crosstalk informed by aging mouse bone transcriptomics and human osteoarthritis genome-wide association studies

Bone Reports, 2023-06, Vol.18, p.101647-101647, Article 101647

2023

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TGF-β Regulates the Mechanical Properties and Composition of Bone Matrix

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (52), p.18813-18818

2005

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Smad4 regulates growth plate matrix production and chondrocyte polarity

Biology open, 2017-03, Vol.6 (3), p.358-364

2017

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Type 2 diabetes impairs annulus fibrosus fiber deformation and rotation under disc compression in the University of California Davis type 2 diabetes mellitus (UCD-T2DM) rat model

PNAS nexus, 2023-12, Vol.2 (12), p.pgad363-pgad363

2023

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Aging impairs the osteocytic regulation of collagen integrity and bone quality

Bone research, 2024-02, Vol.12 (1), p.13-13

2024

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Disrupted bone remodeling leads to cochlear overgrowth and hearing loss in a mouse model of fibrous dysplasia

PloS one, 2014-05, Vol.9 (5), p.e94989-e94989

2014

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Bone Quality Sleuths: Uncovering Tissue‐Level Mechanisms of Bone Fragility in Human Type 2 Diabetes

Journal of bone and mineral research, 2019-07, Vol.34 (7), p.1189-1190

2019

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Glucocorticoids cause mandibular bone fragility and suppress osteocyte perilacunar-canalicular remodeling

Bone Reports, 2018-12, Vol.9, p.145-153

2018

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Pulsed Electromagnetic Fields (PEMF) Inhibit Matrix Metalloproteinase-13 Expression in Human Annulus Fibrosus Cells

The spine journal, 2014-11, Vol.14 (11), p.S167-S167

2014

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Bone marrow lesions in osteoarthritis: What lies beneath

Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistance

Age-related changes in the plasticity and toughness of human cortical bone at multiple length scales

Contributions of Material Properties and Structure to Increased Bone Fragility for a Given Bone Mass in the UCD‐T2DM Rat Model of Type 2 Diabetes

Characterization of the effects of x-ray irradiation on the hierarchical structure and mechanical properties of human cortical bone

How Tough Is Brittle Bone? Investigating Osteogenesis Imperfecta in Mouse Bone

Osteocyte Control of Bone Quality and Fragility in Skeletal Aging

Osteocyte-Intrinsic TGF-β Signaling Regulates Bone Quality through Perilacunar/Canalicular Remodeling

Load regulates bone formation and Sclerostin expression through a TGFβ-dependent mechanism

Smad3 binds scleraxis and mohawk and regulates tendon matrix organization

Deep coverage and quantification of the bone proteome provides enhanced opportunities for new discoveries in skeletal biology and disease

Biologically Regulated Marrow Stimulation by Blocking TGF-β1 With Losartan Oral Administration Results in Hyaline-like Cartilage Repair: A Rabbit Osteochondral Defect Model

Biological Regulation of Bone Quality

Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis

Effects of cell type and configuration on anabolic and catabolic activity in 3D co‐culture of mesenchymal stem cells and nucleus pulposus cells

Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension

Bone-cartilage crosstalk informed by aging mouse bone transcriptomics and human osteoarthritis genome-wide association studies

TGF-β Regulates the Mechanical Properties and Composition of Bone Matrix

Smad4 regulates growth plate matrix production and chondrocyte polarity

Type 2 diabetes impairs annulus fibrosus fiber deformation and rotation under disc compression in the University of California Davis type 2 diabetes mellitus (UCD-T2DM) rat model

Aging impairs the osteocytic regulation of collagen integrity and bone quality

Disrupted bone remodeling leads to cochlear overgrowth and hearing loss in a mouse model of fibrous dysplasia

Bone Quality Sleuths: Uncovering Tissue‐Level Mechanisms of Bone Fragility in Human Type 2 Diabetes

Glucocorticoids cause mandibular bone fragility and suppress osteocyte perilacunar-canalicular remodeling

Pulsed Electromagnetic Fields (PEMF) Inhibit Matrix Metalloproteinase-13 Expression in Human Annulus Fibrosus Cells

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