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Prediction of Liquid–Liquid Phase Separation at the Dissolving Drug Salt Particle Surface

Molecular pharmaceutics, 2023-06, Vol.20 (6), p.3140-3149

2023

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Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

International journal of pharmaceutics, 2009-02, Vol.368 (1-2), p.116-122

Sugano, Kiyohiko

2009

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The Solubility–Permeability Interplay in Using Cyclodextrins as Pharmaceutical Solubilizers: Mechanistic Modeling and Application to Progesterone

Journal of pharmaceutical sciences, 2010-06, Vol.99 (6), p.2739-2749

2010

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Practical Approach to Modeling the Impact of Amorphous Drug Nanoparticles on the Oral Absorption of Poorly Soluble Drugs

Molecular pharmaceutics, 2020-01, Vol.17 (1), p.180-189

2020

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Designing a Novel Coamorphous Salt Formulation of Telmisartan with Amlodipine to Enhance Permeability and Oral Absorption

Molecular pharmaceutics, 2023-08, Vol.20 (8), p.4071-4085

2023

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Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

International journal of pharmaceutics, 2010-03, Vol.387 (1), p.103-109

Sugano, Kiyohiko

2010

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An evaluation of the relative roles of the unstirred water layer and receptor sink in limiting the in-vitro intestinal permeability of drug compounds of varying lipophilicity

Journal of pharmacy and pharmacology, 2008-10, Vol.60 (10), p.1311-1319

2008

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Oral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulations

PloS one, 2013-07, Vol.8 (7), p.e68237-e68237

2013

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Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

European journal of pharmaceutical sciences, 2010-05, Vol.40 (2), p.118-124

2010

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Toward Successful Cyclodextrin Based Solubility-Enabling Formulations for Oral Delivery of Lipophilic Drugs: Solubility–Permeability Trade-Off, Biorelevant Dissolution, and the Unstirred Water Layer

Molecular pharmaceutics, 2017-06, Vol.14 (6), p.2138-2146

2017

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Methacrylate-Copolymer Eudragit EPO as a Solubility-Enabling Excipient for Anionic Drugs: Investigation of Drug Solubility, Intestinal Permeability, and Their Interplay

Molecular pharmaceutics, 2019-07, Vol.16 (7), p.2884-2891

2019

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Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population

International journal of pharmaceutics, 2009-05, Vol.373 (1), p.55-61

Sugano, Kiyohiko

2009

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Physicochemical properties of water and its effect on drug delivery A commentary

International journal of pharmaceutics, 2008-04, Vol.354 (1-2), p.248-254

2008

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Quantitative Investigation of Intestinal Drug Absorption Enhancement by Drug-Rich Nanodroplets Generated via Liquid–Liquid Phase Separation

Molecular pharmaceutics, 2024-04, Vol.21 (4), p.1745-1755

2024

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Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability

European journal of pharmaceutics and biopharmaceutics, 2010-03, Vol.74 (3), p.495-502

2010

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Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters

International journal of pharmaceutics, 2010-08, Vol.395 (1), p.182-197

2010

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Prediction Characteristics of Oral Absorption Simulation Software Evaluated Using Structurally Diverse Low-Solubility Drugs

Journal of pharmaceutical sciences, 2020-03, Vol.109 (3), p.1403-1416

2020

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Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles

Acta pharmaceutica Sinica. B, 2017-05, Vol.7 (3), p.260-280

2017

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‘Stirred not Shaken!’ Comparing Agitation Methods for Permeability Studies Using a Novel Type of 96-Well Sandwich-Plates

Journal of pharmaceutical sciences, 2022-01, Vol.111 (1), p.32-40

2022

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In vitro dissolution testing of respirable size anti-tubercular drug particles using a small volume dissolution apparatus

International journal of pharmaceutics, 2019-03, Vol.559, p.235-244

2019

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In silico Prediction of Human Oral Absorption Based on QSAR Analyses of PAMPA Permeability

Chemistry & biodiversity, 2009-11, Vol.6 (11), p.1845-1866

2009

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50years of oral lipid-based formulations: Provenance, progress and future perspectives

Advanced drug delivery reviews, 2016-06, Vol.101, p.167-194

2016

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Liquid–liquid phase separation drug aggregate: Merit for oral delivery of amorphous solid dispersions

Journal of controlled release, 2023-01, Vol.353, p.42-50

2023

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Recent advances in the engineering of nanosized active pharmaceutical ingredients: Promises and challenges

Advances in colloid and interface science, 2016-02, Vol.228, p.71-91

2016

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Solubility and permeability of steroids in water in the presence of potassium halides

Pharmazie, 2010-02, Vol.65 (2), p.83-85

2010

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Prediction of Liquid–Liquid Phase Separation at the Dissolving Drug Salt Particle Surface

Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

The Solubility–Permeability Interplay in Using Cyclodextrins as Pharmaceutical Solubilizers: Mechanistic Modeling and Application to Progesterone

Practical Approach to Modeling the Impact of Amorphous Drug Nanoparticles on the Oral Absorption of Poorly Soluble Drugs

Designing a Novel Coamorphous Salt Formulation of Telmisartan with Amlodipine to Enhance Permeability and Oral Absorption

Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

An evaluation of the relative roles of the unstirred water layer and receptor sink in limiting the in-vitro intestinal permeability of drug compounds of varying lipophilicity

Oral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulations

Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

Toward Successful Cyclodextrin Based Solubility-Enabling Formulations for Oral Delivery of Lipophilic Drugs: Solubility–Permeability Trade-Off, Biorelevant Dissolution, and the Unstirred Water Layer

Methacrylate-Copolymer Eudragit EPO as a Solubility-Enabling Excipient for Anionic Drugs: Investigation of Drug Solubility, Intestinal Permeability, and Their Interplay

Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population

Physicochemical properties of water and its effect on drug delivery A commentary

Quantitative Investigation of Intestinal Drug Absorption Enhancement by Drug-Rich Nanodroplets Generated via Liquid–Liquid Phase Separation

Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability

Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters

Prediction Characteristics of Oral Absorption Simulation Software Evaluated Using Structurally Diverse Low-Solubility Drugs

Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles

‘Stirred not Shaken!’ Comparing Agitation Methods for Permeability Studies Using a Novel Type of 96-Well Sandwich-Plates

In vitro dissolution testing of respirable size anti-tubercular drug particles using a small volume dissolution apparatus

In silico Prediction of Human Oral Absorption Based on QSAR Analyses of PAMPA Permeability

50years of oral lipid-based formulations: Provenance, progress and future perspectives

Liquid–liquid phase separation drug aggregate: Merit for oral delivery of amorphous solid dispersions

Recent advances in the engineering of nanosized active pharmaceutical ingredients: Promises and challenges

Solubility and permeability of steroids in water in the presence of potassium halides

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