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High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na + channel complex

Scientific reports, 2019-11, Vol.9 (1), p.16890-15, Article 16890

2019

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Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (17), p.6704

2012

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Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.E1857-E1865

2017

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Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

PloS one, 2016-11, Vol.11 (11), p.e0166143

2016

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Modulation of a voltage-gated Na+channel by sevoflurane involves multiple sites and distinct mechanisms

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (18), p.6726-6731

2014

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A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

Nature communications, 2014-07, Vol.5 (1), p.4350-4350, Article 4350

2014

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Morphine decreases enteric neuron excitability via inhibition of sodium channels

PloS one, 2012-09, Vol.7 (9), p.e45251

2012

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Bidirectional influence of sodium channel activation on NMDA receptor–dependent cerebrocortical neuron structural plasticity

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (48), p.19840-19845

2012

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The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development

PloS one, 2017-01, Vol.12 (1), p.e0169882

2017

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Potassium softens vascular endothelium and increases nitric oxide release

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2829-2834

2009

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Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2648-2653

2012

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A sodium-channel mutation causes isolated cardiac conduction disease

Nature (London), 2001-02, Vol.409 (6823), p.1043-1047

2001

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Noninactivating Voltage-Gated Sodium Channels in Severe Myoclonic Epilepsy of Infancy

Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (30), p.11147-11152

2004

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Assessment of TTX-s and TTX-r Action Potential Conduction along Neurites of NGF and GDNF Cultured Porcine DRG Somata

PloS one, 2015-09, Vol.10 (9), p.e0139107-e0139107

2015

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Differential effects of TipE and a TipE-homologous protein on modulation of gating properties of sodium channels from Drosophila melanogaster

PloS one, 2013-07, Vol.8 (7), p.e67551-e67551

2013

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Neuronal activity controls transsynaptic geometry

Scientific reports, 2016-03, Vol.6 (1), p.22703, Article 22703

2016

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Mechanisms of Adaptation in a Predator-Prey Arms Race: TTX-Resistant Sodium Channels

Science (American Association for the Advancement of Science), 2002-08, Vol.297 (5585), p.1336-1339

2002

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Differential toxicity and venom gland gene expression in Centruroides vittatus

PloS one, 2017-10, Vol.12 (10), p.e0184695

2017

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Tetrodotoxin: A brief history

Proceedings of the Japan Academy, Series B, 2008/05/30, Vol.84(5), pp.147-154

NARAHASHI, Toshio

2008

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A Comparison of the Potential Role of the Tetrodotoxin-Insensitive Sodium Channels, PN3/SNS and NaN/SNS2, in Rat Models of Chronic Pain

Proceedings of the National Academy of Sciences - PNAS, 1999-07, Vol.96 (14), p.7640-7644

1999

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An epithelial serine protease activates the amiloride-sensitive sodium channel

Nature (London), 1997-10, Vol.389 (6651), p.607-610

1997

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Genetics: An incomplete mosaic

Nature (London), 2016-07, Vol.535 (7611), p.S12-S13

Brown, Eryn

2016

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A novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic response

PloS one, 2007-12, Vol.2 (12), p.e1258-e1258

2007

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A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

Nature (London), 1996-01, Vol.379 (6562), p.257-262

1996

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High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na + channel complex

Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Modulation of a voltage-gated Na+channel by sevoflurane involves multiple sites and distinct mechanisms

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

Morphine decreases enteric neuron excitability via inhibition of sodium channels

Bidirectional influence of sodium channel activation on NMDA receptor–dependent cerebrocortical neuron structural plasticity

The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development

Potassium softens vascular endothelium and increases nitric oxide release

Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor

A sodium-channel mutation causes isolated cardiac conduction disease

Noninactivating Voltage-Gated Sodium Channels in Severe Myoclonic Epilepsy of Infancy

Assessment of TTX-s and TTX-r Action Potential Conduction along Neurites of NGF and GDNF Cultured Porcine DRG Somata

Differential effects of TipE and a TipE-homologous protein on modulation of gating properties of sodium channels from Drosophila melanogaster

Neuronal activity controls transsynaptic geometry

Mechanisms of Adaptation in a Predator-Prey Arms Race: TTX-Resistant Sodium Channels

Differential toxicity and venom gland gene expression in Centruroides vittatus

Tetrodotoxin: A brief history

A Comparison of the Potential Role of the Tetrodotoxin-Insensitive Sodium Channels, PN3/SNS and NaN/SNS2, in Rat Models of Chronic Pain

An epithelial serine protease activates the amiloride-sensitive sodium channel

Genetics: An incomplete mosaic

A novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic response

A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

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