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Recombinant PaurTx-3, a spider toxin, inhibits sodium channels and decreases membrane excitability in DRG neurons

Biochemical and biophysical research communications, 2020-12, Vol.533 (4), p.958-964

2020

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Modulation of peripheral Na+ channels and neuronal firing by n-butyl-p-aminobenzoate

European journal of pharmacology, 2014-03, Vol.727, p.158-166

2014

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Blocking voltage-gated sodium channels as a strategy to suppress pathological cough

Pulmonary pharmacology & therapeutics, 2017-12, Vol.47, p.38-41

2017

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Mechanism and molecular basis for the sodium channel subtype specificity of µ‐conopeptide CnIIIC

British journal of pharmacology, 2012-10, Vol.167 (3), p.576-586

2012

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ENaC structure and function in the wake of a resolved structure of a family member

American journal of physiology. Renal physiology, 2011-10, Vol.301 (4), p.F684-F696

2011

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High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na + channel complex

Scientific reports, 2019-11, Vol.9 (1), p.16890-15, Article 16890

2019

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Sidedness of carbamazepine accessibility to voltage-gated sodium channels

Molecular pharmacology, 2014-02, Vol.85 (2), p.381-387

2014

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Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

The Journal of biological chemistry, 2020-01, Vol.295 (5), p.1315-1327

2020

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Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin

Marine drugs, 2016-02, Vol.14 (2), p.36

2016

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Ciguatoxins Evoke Potent CGRP Release by Activation of Voltage-Gated Sodium Channel Subtypes Na V 1.9, Na V 1.7 and Na V 1.1

Marine drugs, 2017-08, Vol.15 (9)

2017

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The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5

British journal of pharmacology, 2014-01, Vol.171 (2), p.427

2014

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To4, the first Tityus obscurus β-toxin fully electrophysiologically characterized on human sodium channel isoforms

Peptides (New York, N.Y. : 1980), 2017-09, Vol.95, p.106-115

2017

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Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels

Annual review of pharmacology and toxicology, 2020-01, Vol.60, p.133

2020

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Differential modulation of Nav1.7 and Nav1.8 channels by antidepressant drugs

European journal of pharmacology, 2015-10, Vol.764, p.395-403

2015

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Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC)

Pflügers Archiv, 2014-02, Vol.466 (2), p.253-263

2014

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Targeting voltage gated sodium channels NaV1.7, Na V1.8, and Na V1.9 for treatment of pathological cough

Lung, 2014-02, Vol.192 (1), p.15

2014

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Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells

BMC cardiovascular disorders, 2016-01, Vol.16 (1), p.1-1, Article 1

2016

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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin

Circulation (New York, N.Y.), 2021-06, Vol.143 (22), p.2188-2204

2021

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International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel

Pharmacological reviews, 2015, Vol.67 (1), p.1-35

2015

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Dynamical characterization of inactivation path in voltage-gated Na+ ion channel by non-equilibrium response spectroscopy

Channels (Austin, Tex.), 2016-11, Vol.10 (6), p.478-497

2016

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Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5

Journal of biomolecular screening, 2016-06, Vol.21 (5), p.480-489

2016

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Status of peripheral sodium channel blockers for non-addictive pain treatment

Nature reviews. Neurology, 2020-12, Vol.16 (12), p.689-705

2020

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Aprotinin prevents proteolytic epithelial sodium channel (ENaC) activation and volume retention in nephrotic syndrome

Kidney international, 2018-01, Vol.93 (1), p.159-172

2018

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The Concise Guide to PHARMACOLOGY 2015/16: Voltage‐gated ion channels

British journal of pharmacology, 2015-12, Vol.172 (24), p.5904-5941

2015

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Nav1.7 and other voltage-gated sodium channels as drug targets for pain relief

Expert opinion on therapeutic targets, 2016-08, Vol.20 (8), p.975-983

2016

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Recombinant PaurTx-3, a spider toxin, inhibits sodium channels and decreases membrane excitability in DRG neurons

Modulation of peripheral Na+ channels and neuronal firing by n-butyl-p-aminobenzoate

Blocking voltage-gated sodium channels as a strategy to suppress pathological cough

Mechanism and molecular basis for the sodium channel subtype specificity of µ‐conopeptide CnIIIC

ENaC structure and function in the wake of a resolved structure of a family member

High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na + channel complex

Sidedness of carbamazepine accessibility to voltage-gated sodium channels

Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin

Ciguatoxins Evoke Potent CGRP Release by Activation of Voltage-Gated Sodium Channel Subtypes Na V 1.9, Na V 1.7 and Na V 1.1

The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5

To4, the first Tityus obscurus β-toxin fully electrophysiologically characterized on human sodium channel isoforms

Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels

Differential modulation of Nav1.7 and Nav1.8 channels by antidepressant drugs

Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC)

Targeting voltage gated sodium channels NaV1.7, Na V1.8, and Na V1.9 for treatment of pathological cough

Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells

Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin

International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel

Dynamical characterization of inactivation path in voltage-gated Na+ ion channel by non-equilibrium response spectroscopy

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5

Status of peripheral sodium channel blockers for non-addictive pain treatment

Aprotinin prevents proteolytic epithelial sodium channel (ENaC) activation and volume retention in nephrotic syndrome

The Concise Guide to PHARMACOLOGY 2015/16: Voltage‐gated ion channels

Nav1.7 and other voltage-gated sodium channels as drug targets for pain relief

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