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Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

The Journal of biological chemistry, 2020-01, Vol.295 (5), p.1315-1327

2020

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Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade

The Journal of general physiology, 2007-02, Vol.129 (2), p.161-173

2007

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Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (17), p.6704

2012

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Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.E1857-E1865

2017

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Modulation of a voltage-gated Na+channel by sevoflurane involves multiple sites and distinct mechanisms

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (18), p.6726-6731

2014

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Inhibition of voltage‐gated Na+ currents in sensory neurones by the sea anemone toxin APETx2

British journal of pharmacology, 2012-04, Vol.165 (7), p.2167-2177

2012

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Bidirectional influence of sodium channel activation on NMDA receptor–dependent cerebrocortical neuron structural plasticity

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (48), p.19840-19845

2012

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Evidence for a role of Nav1.6 in facilitating increases in neuronal hyperexcitability during epileptogenesis

Journal of neurophysiology, 2013-09, Vol.110 (5), p.1144-1157

2013

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Potassium softens vascular endothelium and increases nitric oxide release

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2829-2834

2009

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Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2648-2653

2012

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A sodium-channel mutation causes isolated cardiac conduction disease

Nature (London), 2001-02, Vol.409 (6823), p.1043-1047

2001

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Noninactivating Voltage-Gated Sodium Channels in Severe Myoclonic Epilepsy of Infancy

Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (30), p.11147-11152

2004

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beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel

The Journal of general physiology, 2007-09, Vol.130 (3), p.257-268

2007

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Mechanisms of Adaptation in a Predator-Prey Arms Race: TTX-Resistant Sodium Channels

Science (American Association for the Advancement of Science), 2002-08, Vol.297 (5585), p.1336-1339

2002

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Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop

The Journal of biological chemistry, 2004-08, Vol.279 (32), p.33323

2004

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A Comparison of the Potential Role of the Tetrodotoxin-Insensitive Sodium Channels, PN3/SNS and NaN/SNS2, in Rat Models of Chronic Pain

Proceedings of the National Academy of Sciences - PNAS, 1999-07, Vol.96 (14), p.7640-7644

1999

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An epithelial serine protease activates the amiloride-sensitive sodium channel

Nature (London), 1997-10, Vol.389 (6651), p.607-610

1997

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Genetics: An incomplete mosaic

Nature (London), 2016-07, Vol.535 (7611), p.S12-S13

Brown, Eryn

2016

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Common Molecular Determinants of Local Anesthetic, Antiarrhythmic, and Anticonvulsant Block of Voltage-Gated Na+ Channels

Proceedings of the National Academy of Sciences - PNAS, 1996-08, Vol.93 (17), p.9270-9275

1996

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A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

Nature (London), 1996-01, Vol.379 (6562), p.257-262

1996

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Molecular Determinants of State-Dependent Block of Na$^+$ Channels by Local Anesthetics

Science (American Association for the Advancement of Science), 1994-09, Vol.265 (5179), p.1724-1728

1994

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Amiloride-sensitive epithelial Na + channel is made of three homologous subunits

Nature (London), 1994-02, Vol.367 (6462), p.463-467

1994

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Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rat ventricular myocytes

Proceedings of the National Academy of Sciences - PNAS, 1995-11, Vol.92 (24), p.11000-11004

1995

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Hyperalgesic Agents Increase a Tetrodotoxin-Resistant Na+ Current in Nociceptors

Proceedings of the National Academy of Sciences - PNAS, 1996-02, Vol.93 (3), p.1108-1112

1996

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Polyunsaturated Fatty Acids Modulate Sodium and Calcium Currents in CA1 Neurons

Proceedings of the National Academy of Sciences - PNAS, 1996-10, Vol.93 (22), p.12559-12563

1996

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Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade

Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Modulation of a voltage-gated Na+channel by sevoflurane involves multiple sites and distinct mechanisms

Inhibition of voltage‐gated Na+ currents in sensory neurones by the sea anemone toxin APETx2

Bidirectional influence of sodium channel activation on NMDA receptor–dependent cerebrocortical neuron structural plasticity

Evidence for a role of Nav1.6 in facilitating increases in neuronal hyperexcitability during epileptogenesis

Potassium softens vascular endothelium and increases nitric oxide release

Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor

A sodium-channel mutation causes isolated cardiac conduction disease

Noninactivating Voltage-Gated Sodium Channels in Severe Myoclonic Epilepsy of Infancy

beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel

Mechanisms of Adaptation in a Predator-Prey Arms Race: TTX-Resistant Sodium Channels

Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop

A Comparison of the Potential Role of the Tetrodotoxin-Insensitive Sodium Channels, PN3/SNS and NaN/SNS2, in Rat Models of Chronic Pain

An epithelial serine protease activates the amiloride-sensitive sodium channel

Genetics: An incomplete mosaic

Common Molecular Determinants of Local Anesthetic, Antiarrhythmic, and Anticonvulsant Block of Voltage-Gated Na+ Channels

A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

Molecular Determinants of State-Dependent Block of Na$^+$ Channels by Local Anesthetics

Amiloride-sensitive epithelial Na + channel is made of three homologous subunits

Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rat ventricular myocytes

Hyperalgesic Agents Increase a Tetrodotoxin-Resistant Na+ Current in Nociceptors

Polyunsaturated Fatty Acids Modulate Sodium and Calcium Currents in CA1 Neurons

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