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2′-C-methylated nucleotides terminate virus RNA synthesis by preventing active site closure of the viral RNA-dependent RNA polymerase
The Journal of biological chemistry, 2019-11, Vol.294 (45), p.16897-16907
2019
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Modulation of the Nucleoside Triphosphatase/RNA Helicase and 5′-RNA Triphosphatase Activities of Dengue Virus Type 2 Nonstructural Protein 3 (NS3) by Interaction with NS5, the RNA-dependent RNA Polymerase
The Journal of biological chemistry, 2005-07, Vol.280 (29), p.27412-27419
2005
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Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir
The Journal of biological chemistry, 2022-02, Vol.298 (2), p.101529-101529, Article 101529
2022
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Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action
The Journal of biological chemistry, 2020-11, Vol.295 (47), p.16156-16165
2020
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Solution Structures of Cytosolic RNA Sensor MDA5 and LGP2 C-terminal Domains: IDENTIFICATION OF THE RNA RECOGNITION LOOP IN RIG-I-LIKE RECEPTORS
The Journal of biological chemistry, 2009-06, Vol.284 (26), p.17465-17474
2009
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Mechanism and spectrum of inhibition of a 4′-cyano modified nucleotide analog against diverse RNA polymerases of prototypic respiratory RNA viruses
The Journal of biological chemistry, 2024-08, Vol.300 (8), p.107514, Article 107514
2024
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Adenosine deaminase acting on RNA (ADAR1), a suppressor of double-stranded RNA–triggered innate immune responses
The Journal of biological chemistry, 2019-02, Vol.294 (5), p.1710-1720
2019
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The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus
The Journal of biological chemistry, 2020-04, Vol.295 (15), p.4773-4779
2020
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Zika virus noncoding sfRNAs sequester multiple host-derived RNA-binding proteins and modulate mRNA decay and splicing during infection
The Journal of biological chemistry, 2019-11, Vol.294 (44), p.16282-16296
2019
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Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly
The Journal of biological chemistry, 2010-04, Vol.285 (14), p.10959-10968
2010
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RNA Helicase Associated with AU-rich Element (RHAU/DHX36) Interacts with the 3′-Tail of the Long Non-coding RNA BC200 (BCYRN1)
The Journal of biological chemistry, 2016-03, Vol.291 (10), p.5355-5372
2016
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Chemotherapeutic Drugs Inhibit Ribosome Biogenesis at Various Levels
The Journal of biological chemistry, 2010-04, Vol.285 (16), p.12416-12425
2010
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The long noncoding RNA Arrl1 inhibits neurite outgrowth by functioning as a competing endogenous RNA during neuronal regeneration in rats
The Journal of biological chemistry, 2020-06, Vol.295 (25), p.8374-8386
2020
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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency
The Journal of biological chemistry, 2020-05, Vol.295 (20), p.6785-6797
2020
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Picornaviral polymerase domain exchanges reveal a modular basis for distinct biochemical activities of viral RNA-dependent RNA polymerases
The Journal of biological chemistry, 2020-07, Vol.295 (31), p.10624-10637
2020
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Crystal structure of a Y-box binding protein 1 (YB-1)–RNA complex reveals key features and residues interacting with RNA
The Journal of biological chemistry, 2019-07, Vol.294 (28), p.10998-11010
2019
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Revisiting T7 RNA polymerase transcription in vitro with the Broccoli RNA aptamer as a simplified real-time fluorescent reporter
The Journal of biological chemistry, 2021-01, Vol.296, p.100175-100175, Article 100175
2021
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Crystal structures of the RNA triphosphatase from Trypanosoma cruzi provide insights into how it recognizes the 5′-end of the RNA substrate
The Journal of biological chemistry, 2020-07, Vol.295 (27), p.9076-9086
2020
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Bacterial Small RNA-based Negative Regulation: Hfq and Its Accomplices
The Journal of biological chemistry, 2013-03, Vol.288 (12), p.7996-8003
2013
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Bacillus halodurans OapB forms a high-affinity complex with the P13 region of the noncoding RNA OLE
The Journal of biological chemistry, 2020-07, Vol.295 (28), p.9326-9334
2020
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RNA polymerase I (Pol I) passage through nucleosomes depends on Pol I subunits binding its lobe structure
The Journal of biological chemistry, 2020-04, Vol.295 (15), p.4782-4795
2020
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Post-transcriptional regulation of ERBB2 by miR26a/b and HuR confers resistance to tamoxifen in estrogen receptor-positive breast cancer cells
The Journal of biological chemistry, 2017-08, Vol.292 (33), p.13551-13564
2017
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Structures of RNA Complexes with the Escherichia coli RNA Pyrophosphohydrolase RppH Unveil the Basis for Specific 5′-End-dependent mRNA Decay
The Journal of biological chemistry, 2015-04, Vol.290 (15), p.9487-9499
2015
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“Boundary residues” between the folded RNA recognition motif and disordered RGG domains are critical for FUS–RNA binding
The Journal of biological chemistry, 2023-12, Vol.299 (12), p.105392-105392, Article 105392
2023
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Shared requirements for key residues in the antibiotic resistance enzymes ErmC and ErmE suggest a common mode of RNA recognition
The Journal of biological chemistry, 2020-10, Vol.295 (51), p.17476-17485
2020
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