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FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation

The Journal of biological chemistry, 2024-04, Vol.300 (4), p.107209-107209, Article 107209

2024

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Glycolysis-non-canonical glutamine dual-metabolism regulation nanodrug enhanced the phototherapy effect for pancreatic ductal adenocarcinoma treatment

Journal of colloid and interface science, 2024-07, Vol.665, p.477-490

2024

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Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.105763-105763, Article 105763

2024

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Loss of function of phosphatidylserine synthase causes muscle atrophy in Drosophila

Developmental biology, 2024-07, Vol.511, p.1-11

2024

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The human adenovirus PI3K-Akt activator E4orf1 is targeted by the tumor suppressor p53

Journal of virology, 2024-03, Vol.98 (4), p.e0170123

2024

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Targeting CAMK2N1/CAMK2 inhibits invasion, migration and angiogenesis of non-small cell lung cancer by promoting autophagy and apoptosis via AKT/mTOR signaling pathway

Gene, 2024-06, Vol.913, p.148375-148375, Article 148375

2024

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Egg White Peptides Accelerating the Wound Healing Process Through Modulating the PI3K-AKT Pathway: A Joint Analysis of Transcriptomic and Proteomic

Journal of agricultural and food chemistry, 2024-02, Vol.72 (8), p.4100-4115

2024

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Hyaluronan degradation by HYAL2 is essential for odontoblastic differentiation and migration of mouse dental papilla cells

Matrix biology, 2024-05, Vol.129, p.1-14

2024

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LncRNA-LncDACH1 mediated phenotypic switching of smooth muscle cells during neointimal hyperplasia in male arteriovenous fistulas

Nature communications, 2024-05, Vol.15 (1), p.3743-3743

2024

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A mutation in LPAR2 activates the miR-939-5p-LPAR2-PI3K/AKT axis to regulate the proliferation and apoptosis of granulosa cells in sheep

Theriogenology, 2024-04, Vol.219, p.1-10

2024

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Akt Inhibitor Advancements: From Capivasertib Approval to Covalent-Allosteric Promises

Journal of medicinal chemistry, 2024-04, Vol.67 (8), p.6052-6063

2024

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MicroRNA-203a inhibits breast cancer progression through the PI3K/Akt and Wnt pathways

Scientific reports, 2024-02, Vol.14 (1), p.4715-4715

2024

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Differential prognostic values of the three AKT isoforms in acute myeloid leukemia

Scientific reports, 2024-03, Vol.14 (1), p.7070-7070

2024

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Nuciferine reduces vascular leakage and improves cardiac function in acute myocardial infarction by regulating the PI3K/AKT pathway

Scientific reports, 2024-03, Vol.14 (1), p.7086-7086

2024

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FTO‐mediated m6A mRNA demethylation aggravates renal fibrosis by targeting RUNX1 and further enhancing PI3K/AKT pathway

The FASEB journal, 2024-03, Vol.38 (5), p.e23436-n/a

2024

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Verification of AKT and CDK5 Gene and RNA Interference Combined with Irradiation to Mediate Fertility Changes in Plutella xylostella (Linnaeus)

International journal of molecular sciences, 2024-04, Vol.25 (9), p.4623

2024

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PDGFBB facilitates tumorigenesis and malignancy of lung adenocarcinoma associated with PI3K-AKT/MAPK signaling

Scientific reports, 2024-02, Vol.14 (1), p.4191-4191

2024

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Andrographolide sensitizes KRAS-mutant colorectal cancer cells to cetuximab by inhibiting the EGFR/AKT and PDGFRβ/AKT signaling pathways

Phytomedicine (Stuttgart), 2024-04, Vol.126, p.155462-155462, Article 155462

2024

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The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism

Nature communications, 2024-02, Vol.15 (1), p.1879-1879

2024

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Substrate preference of protein kinase B isoforms can vary depending on the cell line

PloS one, 2024-03, Vol.19 (3), p.e0298322-e0298322

2024

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Paeonol alleviates postmenopause-induced neuropsychiatric symptoms through the modulation of GPR30 in ovariectomized mice

Journal of ethnopharmacology, 2024-06, Vol.327, p.118063-118063, Article 118063

2024

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Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport

Journal of ethnopharmacology, 2024-06, Vol.327, p.117946-117946, Article 117946

2024

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Simultaneous and Sensitive Sensing of Intracellular MicroRNA and mRNA for the Detection of the PI3K/AKT Signaling Pathway in Live Cells

Analytical chemistry (Washington), 2024-02, Vol.96 (8), p.3329-3334

2024

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TNF-α signals through ITK-Akt-mTOR to drive CD4 + T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis

Science signaling, 2024-04, Vol.17 (833), p.eadg5678

2024

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FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation

Glycolysis-non-canonical glutamine dual-metabolism regulation nanodrug enhanced the phototherapy effect for pancreatic ductal adenocarcinoma treatment

Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands

Loss of function of phosphatidylserine synthase causes muscle atrophy in Drosophila

The human adenovirus PI3K-Akt activator E4orf1 is targeted by the tumor suppressor p53

Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype

Targeting CAMK2N1/CAMK2 inhibits invasion, migration and angiogenesis of non-small cell lung cancer by promoting autophagy and apoptosis via AKT/mTOR signaling pathway

Egg White Peptides Accelerating the Wound Healing Process Through Modulating the PI3K-AKT Pathway: A Joint Analysis of Transcriptomic and Proteomic

Hyaluronan degradation by HYAL2 is essential for odontoblastic differentiation and migration of mouse dental papilla cells

LncRNA-LncDACH1 mediated phenotypic switching of smooth muscle cells during neointimal hyperplasia in male arteriovenous fistulas

A mutation in LPAR2 activates the miR-939-5p-LPAR2-PI3K/AKT axis to regulate the proliferation and apoptosis of granulosa cells in sheep

Akt Inhibitor Advancements: From Capivasertib Approval to Covalent-Allosteric Promises

MicroRNA-203a inhibits breast cancer progression through the PI3K/Akt and Wnt pathways

Differential prognostic values of the three AKT isoforms in acute myeloid leukemia

Nuciferine reduces vascular leakage and improves cardiac function in acute myocardial infarction by regulating the PI3K/AKT pathway

FTO‐mediated m6A mRNA demethylation aggravates renal fibrosis by targeting RUNX1 and further enhancing PI3K/AKT pathway

Verification of AKT and CDK5 Gene and RNA Interference Combined with Irradiation to Mediate Fertility Changes in Plutella xylostella (Linnaeus)

PDGFBB facilitates tumorigenesis and malignancy of lung adenocarcinoma associated with PI3K-AKT/MAPK signaling

Andrographolide sensitizes KRAS-mutant colorectal cancer cells to cetuximab by inhibiting the EGFR/AKT and PDGFRβ/AKT signaling pathways

The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism

Substrate preference of protein kinase B isoforms can vary depending on the cell line

Paeonol alleviates postmenopause-induced neuropsychiatric symptoms through the modulation of GPR30 in ovariectomized mice

Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport

Simultaneous and Sensitive Sensing of Intracellular MicroRNA and mRNA for the Detection of the PI3K/AKT Signaling Pathway in Live Cells

TNF-α signals through ITK-Akt-mTOR to drive CD4 + T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis

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