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Neural KCNQ (Kv7) channels

British journal of pharmacology, 2009-04, Vol.156 (8), p.1185-1195

2009

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Phenytoin and phenobarbital inhibit human HERG potassium channels

Epilepsy research, 2003-06, Vol.55 (1), p.147-157

2003

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Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

Science (American Association for the Advancement of Science), 2010-01, Vol.327 (5963), p.348-351

2010

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Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

The New England journal of medicine, 2010-10, Vol.363 (15), p.1397-1409

2010

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Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers

Blood, 2011-01, Vol.117 (3), p.902-914

2011

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Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog

Circulation (New York, N.Y.), 2014-01, Vol.129 (4), p.430-440

2014

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Anti-proliferative effect of Kv1.3 blockers in A549 human lung adenocarcinoma in vitro and in vivo

European journal of pharmacology, 2011-01, Vol.651 (1-3), p.26-32

2011

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Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

Nature, 2006-04, Vol.440 (7086), p.959-962

2006

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A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties

Biochemical pharmacology, 2011-07, Vol.82 (1), p.81-90

2011

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The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?

Drug discovery today, 2009-11, Vol.14 (21), p.1011-1020

2009

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Pharmacology of cardiac potassium channels

Cardiovascular research, 2004-04, Vol.62 (1), p.9-33

2004

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Chronic Stress Causes Amygdala Hyperexcitability in Rodents

Biological psychiatry (1969), 2010-06, Vol.67 (12), p.1128-1136

2010

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Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model

Pain (Amsterdam), 2013-03, Vol.154 (3), p.434

2013

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ATP-dependent potassium channel blockade strengthens microglial neuroprotection after hypoxia–ischemia in rats

Experimental neurology, 2012-05, Vol.235 (1), p.282-296

2012

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Medicinal Chemistry of hERG Optimizations: Highlights and Hang-Ups

Journal of medicinal chemistry, 2006-08, Vol.49 (17), p.5029-5046

2006

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Disease characterization using LQTS-specific induced pluripotent stem cells

Cardiovascular research, 2012-09, Vol.95 (4), p.419-429

2012

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BK channel modulators: a comprehensive overview

Current medicinal chemistry, 2008-05, Vol.15 (11), p.1126

2008

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Effects of a Highly Selective Acetylcholine-Activated K+ Channel Blocker on Experimental Atrial Fibrillation

Circulation. Arrhythmia and electrophysiology, 2011-02, Vol.4 (1), p.94-102

2011

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Toxin modulators and blockers of hERG K+ channels

Toxicon (Oxford), 2012-09, Vol.60 (4), p.492-501

2012

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A binary QSAR model for classification of hERG potassium channel blockers

Bioorganic & medicinal chemistry, 2008-04, Vol.16 (7), p.4107-4119

2008

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Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine

Neurology, 2004-05, Vol.62 (9), p.1623

2004

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Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by Kv1.3 channel blockers

Cardiovascular research, 2011-02, Vol.89 (2), p.282-289

2011

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Acquired Dendritic Channelopathy in Temporal Lobe Epilepsy

Science (American Association for the Advancement of Science), 2004-07, Vol.305 (5683), p.532-535

2004

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Geraniol Blocks Calcium and Potassium Channels in the Mammalian Myocardium: Useful Effects to Treat Arrhythmias

Basic & clinical pharmacology & toxicology, 2014-12, Vol.115 (6), p.534-544

2014

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Inhibition of Small-Conductance Ca2+-Activated K+ Channels Terminates and Protects Against Atrial Fibrillation

Circulation. Arrhythmia and electrophysiology, 2010-08, Vol.3 (4), p.380-390

2010

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Neural KCNQ (Kv7) channels

Phenytoin and phenobarbital inhibit human HERG potassium channels

Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers

Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog

Anti-proliferative effect of Kv1.3 blockers in A549 human lung adenocarcinoma in vitro and in vivo

Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties

The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?

Pharmacology of cardiac potassium channels

Chronic Stress Causes Amygdala Hyperexcitability in Rodents

Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model

ATP-dependent potassium channel blockade strengthens microglial neuroprotection after hypoxia–ischemia in rats

Medicinal Chemistry of hERG Optimizations: Highlights and Hang-Ups

Disease characterization using LQTS-specific induced pluripotent stem cells

BK channel modulators: a comprehensive overview

Effects of a Highly Selective Acetylcholine-Activated K+ Channel Blocker on Experimental Atrial Fibrillation

Toxin modulators and blockers of hERG K+ channels

A binary QSAR model for classification of hERG potassium channel blockers

Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine

Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by Kv1.3 channel blockers

Acquired Dendritic Channelopathy in Temporal Lobe Epilepsy

Geraniol Blocks Calcium and Potassium Channels in the Mammalian Myocardium: Useful Effects to Treat Arrhythmias

Inhibition of Small-Conductance Ca2+-Activated K+ Channels Terminates and Protects Against Atrial Fibrillation

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