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Kv1.3 in the spotlight for treating immune diseases

Expert opinion on therapeutic targets, 2024, Vol.28 (1-2), p.67-82

2024

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A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle

eLife, 2024-02, Vol.12

2024

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The Sobering Sting: Oleoyl Serotonin Is a Novel Stephanoconus Snail Venom-Derived Antagonist of Cannabinoid Receptors That Counteracts Learning and Memory Deficits

Biomedicines, 2024-02, Vol.12 (2), p.454

2024

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PTHrP attenuates spontaneous contractions in detrusor smooth muscle of the rat bladder by activating spontaneous transient outward potassium currents

Pflügers Archiv, 2024-02, Vol.476 (5), p.809-820

2024

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Pharmacokinetics and Pharmacodynamics of Etripamil, an Intranasally Administered, Fast‐Acting, Nondihydropyridine Calcium Channel Blocker

Clinical pharmacology in drug development, 2024-04, Vol.13 (4), p.367-379

2024

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Do calcium channel blockers applied to cardiomyocytes cause increased channel expression resulting in reduced efficacy?

NPJ systems biology and applications, 2024-03, Vol.10 (1), p.22-22

2024

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The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue

FEBS letters, 2024-04, Vol.598 (8), p.889-901

2024

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Effects of allisartan‐isoproxil‐based combination antihypertensive regimen in hypertensive patients with microalbuminuria or hyperuricemia

The journal of clinical hypertension (Greenwich, Conn.), 2024-03, Vol.26 (3), p.241-250

2024

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Chronic but not acute nicotine treatment ameliorates acute inflammation‐induced working memory impairment by increasing CRTC1 and HCN2 in adult male mice

CNS neuroscience & therapeutics, 2024-02, Vol.30 (2), p.e14627-n/a

2024

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Modelling and analysis of cAMP-induced mixed-mode oscillations in cortical neurons: Critical roles of HCN and M-type potassium channels

PLoS computational biology, 2024-03, Vol.20 (3), p.e1011559-e1011559

2024

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Dilation of Pregnant Rat Uterine Arteries with Phenols from Extra Virgin Olive Oil Is Endothelium-Dependent and Involves Calcium and Potassium Channels

Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.619

2024

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Vasodilation and Blood Pressure-Lowering Effect of 3-Demethyl-2-Geranyl-4-Prenylbellidifoline, a Xanthone Obtained from Garcinia achachairu , in Hypertensive Rats

Plants (Basel), 2024-02, Vol.13 (4), p.528

2024

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The difference in endothelium‐dependent relaxation components in proximal and distal thoracic aorta regions of male rats

Physiological reports, 2024-03, Vol.12 (6), p.e15992-n/a

2024

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Up-regulated expression of two-pore domain K + channels, KCNK1 and KCNK2, is involved in the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary arterial hypertension

Frontiers in cardiovascular medicine, 2024, Vol.11, p.1343804-1343804

2024

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Sakuranetin as a Potential Regulator of Blood Pressure in Spontaneously Hypertensive Rats by Promoting Vasorelaxation through Calcium Channel Blockade

Biomedicines, 2024-02, Vol.12 (2), p.346

2024

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Exploring the Role of Surface and Mitochondrial ATP-Sensitive Potassium Channels in Cancer: From Cellular Functions to Therapeutic Potentials

International journal of molecular sciences, 2024-02, Vol.25 (4), p.2129

Moon, Dong-Oh

2024

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Stimulation of the calcium‐sensing receptor induces relaxations of rat mesenteric arteries by endothelium‐dependent and ‐independent pathways via BKCa and KATP channels

Physiological reports, 2024-01, Vol.12 (2), p.e15926-n/a

2024

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Targeting the hERG1 and β1 integrin complex for cancer treatment

Expert opinion on therapeutic targets, 2024-02, p.1-13

2024

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Spironolactone Induces Vasodilation by Endothelium-Dependent Mechanisms Involving NO and by Endothelium-Independent Mechanisms Blocking Ca2+ Channels

Journal of xenobiotics, 2024-03, Vol.14 (1), p.320-332

2024

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Paternal preconception alcohol consumption increased Angiotensin II‐mediated vasoconstriction in male offspring cerebral arteries via oxidative stress‐AT1R pathway

Addiction biology, 2024-03, Vol.29 (3), p.e13385-n/a

2024

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Phillygenin Suppresses Glutamate Exocytosis in Rat Cerebrocortical Nerve Terminals (Synaptosomes) through the Inhibition of Cav2.2 Calcium Channels

Biomedicines, 2024-03, Vol.12 (3), p.495

2024

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Nephrotic Syndrome: From Pathophysiology to Novel Therapeutic Approaches

Biomedicines, 2024-03, Vol.12 (3), p.569

2024

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Predicting Cardiotoxicity of Molecules Using Attention-Based Graph Neural Networks

Journal of chemical information and modeling, 2024-03, Vol.64 (6), p.1816-1827

2024

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Pathophysiological Roles of Ion Channels in Epidermal Cells, Immune Cells, and Sensory Neurons in Psoriasis

International journal of molecular sciences, 2024-03, Vol.25 (5), p.2756

2024

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Kv1.3 in the spotlight for treating immune diseases

A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle

The Sobering Sting: Oleoyl Serotonin Is a Novel Stephanoconus Snail Venom-Derived Antagonist of Cannabinoid Receptors That Counteracts Learning and Memory Deficits

PTHrP attenuates spontaneous contractions in detrusor smooth muscle of the rat bladder by activating spontaneous transient outward potassium currents

Pharmacokinetics and Pharmacodynamics of Etripamil, an Intranasally Administered, Fast‐Acting, Nondihydropyridine Calcium Channel Blocker

Do calcium channel blockers applied to cardiomyocytes cause increased channel expression resulting in reduced efficacy?

The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue

Effects of allisartan‐isoproxil‐based combination antihypertensive regimen in hypertensive patients with microalbuminuria or hyperuricemia

Chronic but not acute nicotine treatment ameliorates acute inflammation‐induced working memory impairment by increasing CRTC1 and HCN2 in adult male mice

Modelling and analysis of cAMP-induced mixed-mode oscillations in cortical neurons: Critical roles of HCN and M-type potassium channels

Efficacy and Safety of Esaxerenone in Hypertensive Patients with Left Ventricular Hypertrophy (ESES-LVH) Study: A Multicenter, Open-Label, Prospective, Interventional Study

Dilation of Pregnant Rat Uterine Arteries with Phenols from Extra Virgin Olive Oil Is Endothelium-Dependent and Involves Calcium and Potassium Channels

Vasodilation and Blood Pressure-Lowering Effect of 3-Demethyl-2-Geranyl-4-Prenylbellidifoline, a Xanthone Obtained from Garcinia achachairu , in Hypertensive Rats

The difference in endothelium‐dependent relaxation components in proximal and distal thoracic aorta regions of male rats

Up-regulated expression of two-pore domain K + channels, KCNK1 and KCNK2, is involved in the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary arterial hypertension

Sakuranetin as a Potential Regulator of Blood Pressure in Spontaneously Hypertensive Rats by Promoting Vasorelaxation through Calcium Channel Blockade

Exploring the Role of Surface and Mitochondrial ATP-Sensitive Potassium Channels in Cancer: From Cellular Functions to Therapeutic Potentials

Stimulation of the calcium‐sensing receptor induces relaxations of rat mesenteric arteries by endothelium‐dependent and ‐independent pathways via BKCa and KATP channels

Targeting the hERG1 and β1 integrin complex for cancer treatment

Spironolactone Induces Vasodilation by Endothelium-Dependent Mechanisms Involving NO and by Endothelium-Independent Mechanisms Blocking Ca2+ Channels

Paternal preconception alcohol consumption increased Angiotensin II‐mediated vasoconstriction in male offspring cerebral arteries via oxidative stress‐AT1R pathway

Phillygenin Suppresses Glutamate Exocytosis in Rat Cerebrocortical Nerve Terminals (Synaptosomes) through the Inhibition of Cav2.2 Calcium Channels

Nephrotic Syndrome: From Pathophysiology to Novel Therapeutic Approaches

Predicting Cardiotoxicity of Molecules Using Attention-Based Graph Neural Networks

Pathophysiological Roles of Ion Channels in Epidermal Cells, Immune Cells, and Sensory Neurons in Psoriasis

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