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Neural KCNQ (Kv7) channels

British journal of pharmacology, 2009-04, Vol.156 (8), p.1185-1195

2009

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Phenytoin and phenobarbital inhibit human HERG potassium channels

Epilepsy research, 2003-06, Vol.55 (1), p.147-157

2003

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Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

Science (American Association for the Advancement of Science), 2010-01, Vol.327 (5963), p.348-351

2010

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Crystal Structure of the Human K2P TRAAK, a Lipid-and Mechano-Sensitive K⁺ Ion Channel

Science (American Association for the Advancement of Science), 2012-01, Vol.335 (6067), p.436-441

2012

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Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

The New England journal of medicine, 2010-10, Vol.363 (15), p.1397-1409

2010

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Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers

Blood, 2011-01, Vol.117 (3), p.902-914

2011

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Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog

Circulation (New York, N.Y.), 2014-01, Vol.129 (4), p.430-440

2014

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Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 Å Resolution

Science (American Association for the Advancement of Science), 2009-12, Vol.326 (5960), p.1668-1674

2009

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Anti-proliferative effect of Kv1.3 blockers in A549 human lung adenocarcinoma in vitro and in vivo

European journal of pharmacology, 2011-01, Vol.651 (1-3), p.26-32

2011

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Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

Nature, 2006-04, Vol.440 (7086), p.959-962

2006

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A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties

Biochemical pharmacology, 2011-07, Vol.82 (1), p.81-90

2011

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The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?

Drug discovery today, 2009-11, Vol.14 (21), p.1011-1020

2009

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Pharmacology of cardiac potassium channels

Cardiovascular research, 2004-04, Vol.62 (1), p.9-33

2004

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Chronic Stress Causes Amygdala Hyperexcitability in Rodents

Biological psychiatry (1969), 2010-06, Vol.67 (12), p.1128-1136

2010

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Neuronal basis of age-related working memory decline

Nature (London), 2011-08, Vol.476 (7359), p.210-213

2011

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Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model

Pain (Amsterdam), 2013-03, Vol.154 (3), p.434

2013

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ATP-dependent potassium channel blockade strengthens microglial neuroprotection after hypoxia–ischemia in rats

Experimental neurology, 2012-05, Vol.235 (1), p.282-296

2012

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Medicinal Chemistry of hERG Optimizations: Highlights and Hang-Ups

Journal of medicinal chemistry, 2006-08, Vol.49 (17), p.5029-5046

2006

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Disease characterization using LQTS-specific induced pluripotent stem cells

Cardiovascular research, 2012-09, Vol.95 (4), p.419-429

2012

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Endothelium-Dependent Cerebral Artery Dilation Mediated by TRPA1 and Ca2+-Activated K+ Channels

Circulation research, 2009-04, Vol.104 (8), p.987-994

2009

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BK channel modulators: a comprehensive overview

Current medicinal chemistry, 2008-05, Vol.15 (11), p.1126

2008

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Acidosis Dilates Brain Parenchymal Arterioles by Conversion of Calcium Waves to Sparks to Activate BK Channels

Circulation research, 2012-01, Vol.110 (2), p.285-294

2012

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Effects of a Highly Selective Acetylcholine-Activated K+ Channel Blocker on Experimental Atrial Fibrillation

Circulation. Arrhythmia and electrophysiology, 2011-02, Vol.4 (1), p.94-102

2011

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Extracellular Ca²⁺ Ameliorates NaCl-Induced K⁺ Loss from Arabidopsis Root and Leaf Cells by Controlling Plasma Membrane K⁺-Permeable Channels

Plant physiology (Bethesda), 2006-08, Vol.141 (4), p.1653-1665

2006

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An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways

Pain (Amsterdam), 2013-09, Vol.154 (9), p.1749

2013

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Neural KCNQ (Kv7) channels

Phenytoin and phenobarbital inhibit human HERG potassium channels

Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

Crystal Structure of the Human K2P TRAAK, a Lipid-and Mechano-Sensitive K⁺ Ion Channel

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers

Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog

Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 Å Resolution

Anti-proliferative effect of Kv1.3 blockers in A549 human lung adenocarcinoma in vitro and in vivo

Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties

The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?

Pharmacology of cardiac potassium channels

Chronic Stress Causes Amygdala Hyperexcitability in Rodents

Neuronal basis of age-related working memory decline

Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model

ATP-dependent potassium channel blockade strengthens microglial neuroprotection after hypoxia–ischemia in rats

Medicinal Chemistry of hERG Optimizations: Highlights and Hang-Ups

Disease characterization using LQTS-specific induced pluripotent stem cells

Endothelium-Dependent Cerebral Artery Dilation Mediated by TRPA1 and Ca2+-Activated K+ Channels

BK channel modulators: a comprehensive overview

Acidosis Dilates Brain Parenchymal Arterioles by Conversion of Calcium Waves to Sparks to Activate BK Channels

Effects of a Highly Selective Acetylcholine-Activated K+ Channel Blocker on Experimental Atrial Fibrillation

Extracellular Ca²⁺ Ameliorates NaCl-Induced K⁺ Loss from Arabidopsis Root and Leaf Cells by Controlling Plasma Membrane K⁺-Permeable Channels

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways

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