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Kv1.3 in the spotlight for treating immune diseases

Expert opinion on therapeutic targets, 2024, Vol.28 (1-2), p.67-82

2024

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Kv1.3: a multifunctional channel with many pathological implications

Expert opinion on therapeutic targets, 2018-02, Vol.22 (2), p.101-105

2018

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Emerging therapeutic targets in the short QT syndrome

Expert opinion on therapeutic targets, 2018-05, Vol.22 (5), p.439-451

2018

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A BK (Slo1) channel journey from molecule to physiology

Channels (Austin, Tex.), 2013-11, Vol.7 (6), p.442-458

2013

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Machine-learning technique, QSAR and molecular dynamics for hERG-drug interactions

Journal of biomolecular structure & dynamics, 2023, Vol.41 (23), p.13766-13791

2023

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Binding modes of hERG blockers: an unsolved mystery in the drug design arena

Expert opinion on drug discovery, 2018-03, Vol.13 (3), p.207-210

2018

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Dalfampridine: a brief review of its mechanism of action and efficacy as a treatment to improve walking in patients with multiple sclerosis

Current medical research and opinion, 2011-07, Vol.27 (7), p.1415-1423

2011

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The inhibitory effects of pimozide, an antipsychotic drug, on voltage-gated K+ channels in rabbit coronary arterial smooth muscle cells

Drug and chemical toxicology (New York, N.Y. 1978), 2023-03, Vol.46 (2), p.271-280

2023

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Heterogeneity in Kv7 Channel Function in the Cerebral and Coronary Circulation

Microcirculation (New York, N.Y. 1994), 2015-02, Vol.22 (2), p.109-121

2015

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Novel screening techniques for ion channel targeting drugs

Channels (Austin, Tex.), 2015-11, Vol.9 (6), p.367-375

2015

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Excitability of oxytocin neurons in paraventricular nucleus is regulated by voltage-gated potassium channels Kv4.2 and Kv4.3

Bioscience, biotechnology, and biochemistry, 2019-02, Vol.83 (2), p.202-211

2019

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HPLC-based activity profiling for pharmacologically and toxicologically relevant natural products - principles and recent examples

Pharmaceutical biology, 2019-01, Vol.57 (1), p.328-334

Hamburger, Matthias

2019

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Kv1.3 channels facilitate the connection between metabolism and blood flow in the heart

Microcirculation (New York, N.Y. 1994), 2017-05, Vol.24 (4), p.n/a

2017

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Recombinant scorpion toxins: Focus on four-disulfide peptide blockers of Kv1-channels

Bioengineered, 2018-01, Vol.9 (1), p.25-29

2018

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Targeting cardiac potassium channels for state-of-the-art drug discovery

Expert opinion on drug discovery, 2015-02, Vol.10 (2), p.157-169

Walsh, Kenneth B

2015

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Dynamics and modulation studies of human voltage gated Kv1.5 channel

Journal of biomolecular structure & dynamics, 2017-01, Vol.35 (2), p.380-398

2017

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Inhibitory Effects of Methylglyoxal on Light-Induced Stomatal Opening and Inward K+ Channel Activity in Arabidopsis

Bioscience, biotechnology, and biochemistry, 2012, Vol.76 (3), p.617-619

2012

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Inhibitors of the renal outer medullary potassium channel: a patent review

Expert opinion on therapeutic patents, 2015-09, Vol.25 (9), p.1035-1051

2015

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State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1

Channels (Austin, Tex.), 2012-11, Vol.6 (6), p.473-478

2012

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Recent developments in ion channel pharmacology

Channels (Austin, Tex.), 2015-11, Vol.9 (6), p.335-335

2015

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Assessing the role of IKCa channels in generating the sAHP of CA1 hippocampal pyramidal cells

Channels (Austin, Tex.), 2016-07, Vol.10 (4), p.313-319

2016

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Novel Kv1.3 blockers for immunosuppression: WO2012155199

Expert opinion on therapeutic patents, 2013-11, Vol.23 (11), p.1511-1516

Nguyen, William

2013

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Pharmacology and clinical efficacy of dalfampridine for treating multiple sclerosis

Expert opinion on drug metabolism & toxicology, 2015-02, Vol.11 (2), p.295-306

Lugaresi, Alessandra

2015

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4,4′-Diisothiocyanatostilbene-2,2′-disulfonate modulates voltage-gated K+ current and influences cell cycle arrest in androgen sensitive and insensitive human prostate cancer cell lines

Toxicology mechanisms and methods, 2020-06, Vol.ahead-of-print (ahead-of-print), p.1-12

2020

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Hydrogen sulfide augments the proliferation and survival of human induced pluripotent stem cell–derived mesenchymal stromal cells through inhibition of BKCa

Cytotherapy (Oxford, England), 2013-11, Vol.15 (11), p.1395-1405

2013

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Kv1.3 in the spotlight for treating immune diseases

Kv1.3: a multifunctional channel with many pathological implications

Emerging therapeutic targets in the short QT syndrome

A BK (Slo1) channel journey from molecule to physiology

Machine-learning technique, QSAR and molecular dynamics for hERG-drug interactions

Binding modes of hERG blockers: an unsolved mystery in the drug design arena

Dalfampridine: a brief review of its mechanism of action and efficacy as a treatment to improve walking in patients with multiple sclerosis

The inhibitory effects of pimozide, an antipsychotic drug, on voltage-gated K+ channels in rabbit coronary arterial smooth muscle cells

Heterogeneity in Kv7 Channel Function in the Cerebral and Coronary Circulation

Novel screening techniques for ion channel targeting drugs

Excitability of oxytocin neurons in paraventricular nucleus is regulated by voltage-gated potassium channels Kv4.2 and Kv4.3

HPLC-based activity profiling for pharmacologically and toxicologically relevant natural products - principles and recent examples

Kv1.3 channels facilitate the connection between metabolism and blood flow in the heart

Recombinant scorpion toxins: Focus on four-disulfide peptide blockers of Kv1-channels

Targeting cardiac potassium channels for state-of-the-art drug discovery

Dynamics and modulation studies of human voltage gated Kv1.5 channel

Inhibitory Effects of Methylglyoxal on Light-Induced Stomatal Opening and Inward K+ Channel Activity in Arabidopsis

Inhibitors of the renal outer medullary potassium channel: a patent review

State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1

Recent developments in ion channel pharmacology

Assessing the role of IKCa channels in generating the sAHP of CA1 hippocampal pyramidal cells

Novel Kv1.3 blockers for immunosuppression: WO2012155199

Pharmacology and clinical efficacy of dalfampridine for treating multiple sclerosis

4,4′-Diisothiocyanatostilbene-2,2′-disulfonate modulates voltage-gated K+ current and influences cell cycle arrest in androgen sensitive and insensitive human prostate cancer cell lines

Hydrogen sulfide augments the proliferation and survival of human induced pluripotent stem cell–derived mesenchymal stromal cells through inhibition of BKCa

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