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Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls

Journal of biomolecular screening, 2015-10, Vol.20 (9), p.1055-1073

2015

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KCNQ2/3/5 channels in dorsal root ganglion neurons can be therapeutic targets of neuropathic pain in diabetic rats

Molecular pain, 2018-01, Vol.14, p.1744806918793229

2018

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A Proof-of-Concept Evaluation of JTPc and Tp-Tec as Proarrhythmia Biomarkers in Preclinical Species: A Retrospective Analysis by an HESI-Sponsored Consortium

International journal of toxicology, 2019-01, Vol.38 (1), p.23-32

2019

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Effects of the KIR7.1 Blocker VU590 on Spontaneous and Agonist-Induced Contractions of Human Pregnant Myometrium

Reproductive sciences (Thousand Oaks, Calif.), 2017-10, Vol.24 (10), p.1402-1409

2017

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Minimal clinically important difference of improvement on the Arm Function in Multiple Sclerosis Questionnaire (AMSQ)

Multiple sclerosis, 2020-04, Vol.26 (4), p.505-508

2020

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Activation of Peripheral KCNQ Channels Attenuates Inflammatory Pain

Molecular pain, 2014-02, Vol.10 (1), p.15-15

2014

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The stress protein heat shock cognate 70 (Hsc70) inhibits the Transient Receptor Potential Vanilloid type 1 (TRPV1) channel

Molecular pain, 2016, Vol.12, p.174480691666394

2016

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A High-Throughput Electrophysiology Assay Identifies Inhibitors of the Inwardly Rectifying Potassium Channel Kir7.1

Journal of biomolecular screening, 2015-07, Vol.20 (6), p.739-747

2015

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Microfluidic cell culture and its application in high-throughput drug screening: cardiotoxicity assay for hERG channels

Journal of biomolecular screening, 2011-01, Vol.16 (1), p.101-111

2011

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A thallium-sensitive, fluorescence-based assay for detecting and characterizing potassium channel modulators in mammalian cells

Journal of biomolecular screening, 2004-12, Vol.9 (8), p.671-677

2004

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Effects of cooling temperatures and low pH on membrane properties and voltage-dependent currents of rat nociceptive-like trigeminal ganglion neurons

Molecular pain, 2018-01, Vol.14, p.1744806918814350-1744806918814350

2018

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The Effect of Progesterone on Myometrial Contractility, Potassium Channels, and Tocolytic Efficacy

Reproductive sciences (Thousand Oaks, Calif.), 2009-11, Vol.16 (11), p.1052-1061

2009

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Effects of Potassium Channel Blockers on Changes in Refractoriness of Atrial Cardiomyocytes Induced by Stretch

Experimental biology and medicine (Maywood, N.J.), 2009-07, Vol.234 (7), p.779-784

2009

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Adenosine A Receptor Antagonist and Mitochondrial ATP-Sensitive Potassium Channel Blocker Attenuate the Tolerance to Focal Cerebral Ischemia in Rats

Journal of cerebral blood flow and metabolism, 2004-07, Vol.24 (7), p.771-779

2004

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Dalfampridine: a medication to improve walking in patients with multiple sclerosis

The Annals of pharmacotherapy, 2012-07, Vol.46 (7-8), p.1010-1015

2012

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Cerebrovascular Vasodilation to Extraluminal Acidosis Occurs via Combined Activation of ATP-Sensitive and Ca2+-Activated Potassium Channels

Journal of cerebral blood flow and metabolism, 2003-10, Vol.23 (10), p.1227-1238

2003

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Large Conductance Calcium-Activated Potassium Channels (BKCa) Modulate Trigeminovascular Nociceptive Transmission

Cephalalgia, 2009-12, Vol.29 (12), p.1242-1258

2009

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Bilirubin oxidation end products directly alter K channels important in the regulation of vascular tone

Journal of cerebral blood flow and metabolism, 2011-01, Vol.31 (1), p.102-112

2011

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Photoperiod Modulates Fast Delayed Rectifier Potassium Currents in the Mammalian Circadian Clock

ASN neuro, 2016-10, Vol.8 (5), p.175909141667077

2016

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Electrophysiological Characterization and Antiarrhythmic Efficacy of the Mixed Potassium Channel-Blocking Antiarrhythmic Agent AZ13395438 In Vitro and In Vivo

Journal of cardiovascular pharmacology and therapeutics, 2013-05, Vol.18 (3), p.290-300

2013

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The Effects of Pomegranate Seed Extract and β-Sitosterol on Rat Uterine Contractions

Reproductive sciences (Thousand Oaks, Calif.), 2010-03, Vol.17 (3), p.288-296

2010

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Vernakalant in the management of atrial fibrillation

The Annals of pharmacotherapy, 2008-04, Vol.42 (4), p.533-542

Cheng, Judy W M

2008

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Tizanidine (Zanaflex): A Muscle Relaxant That May Prolong the QT Interval by Blocking IKr

Journal of cardiovascular pharmacology and therapeutics, 2012-03, Vol.17 (1), p.102-109

2012

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High-Throughput Screening for Kv1.3 Channel Blockers Using an Improved FLIPR-Based Membrane-Potential Assay

Journal of biomolecular screening, 2010-02, Vol.15 (2), p.185-195

2010

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Spreading depression in the brainstem of the adult rat: electrophysiological parameters and influences on regional brainstem blood flow

Journal of cerebral blood flow and metabolism, 2008-05, Vol.28 (5), p.984-994

2008

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Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls

KCNQ2/3/5 channels in dorsal root ganglion neurons can be therapeutic targets of neuropathic pain in diabetic rats

A Proof-of-Concept Evaluation of JTPc and Tp-Tec as Proarrhythmia Biomarkers in Preclinical Species: A Retrospective Analysis by an HESI-Sponsored Consortium

Effects of the KIR7.1 Blocker VU590 on Spontaneous and Agonist-Induced Contractions of Human Pregnant Myometrium

Minimal clinically important difference of improvement on the Arm Function in Multiple Sclerosis Questionnaire (AMSQ)

Activation of Peripheral KCNQ Channels Attenuates Inflammatory Pain

The stress protein heat shock cognate 70 (Hsc70) inhibits the Transient Receptor Potential Vanilloid type 1 (TRPV1) channel

A High-Throughput Electrophysiology Assay Identifies Inhibitors of the Inwardly Rectifying Potassium Channel Kir7.1

Microfluidic cell culture and its application in high-throughput drug screening: cardiotoxicity assay for hERG channels

A thallium-sensitive, fluorescence-based assay for detecting and characterizing potassium channel modulators in mammalian cells

Effects of cooling temperatures and low pH on membrane properties and voltage-dependent currents of rat nociceptive-like trigeminal ganglion neurons

The Effect of Progesterone on Myometrial Contractility, Potassium Channels, and Tocolytic Efficacy

Effects of Potassium Channel Blockers on Changes in Refractoriness of Atrial Cardiomyocytes Induced by Stretch

Adenosine A Receptor Antagonist and Mitochondrial ATP-Sensitive Potassium Channel Blocker Attenuate the Tolerance to Focal Cerebral Ischemia in Rats

Dalfampridine: a medication to improve walking in patients with multiple sclerosis

Cerebrovascular Vasodilation to Extraluminal Acidosis Occurs via Combined Activation of ATP-Sensitive and Ca2+-Activated Potassium Channels

Large Conductance Calcium-Activated Potassium Channels (BKCa) Modulate Trigeminovascular Nociceptive Transmission

Bilirubin oxidation end products directly alter K channels important in the regulation of vascular tone

Photoperiod Modulates Fast Delayed Rectifier Potassium Currents in the Mammalian Circadian Clock

Electrophysiological Characterization and Antiarrhythmic Efficacy of the Mixed Potassium Channel-Blocking Antiarrhythmic Agent AZ13395438 In Vitro and In Vivo

The Effects of Pomegranate Seed Extract and β-Sitosterol on Rat Uterine Contractions

Vernakalant in the management of atrial fibrillation

Tizanidine (Zanaflex): A Muscle Relaxant That May Prolong the QT Interval by Blocking IKr

High-Throughput Screening for Kv1.3 Channel Blockers Using an Improved FLIPR-Based Membrane-Potential Assay

Spreading depression in the brainstem of the adult rat: electrophysiological parameters and influences on regional brainstem blood flow

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