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Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanism

Science (American Association for the Advancement of Science), 2016-08, Vol.353 (6300), p.664-669

2016

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Potassium channel dysfunction in human neuronal models of Angelman syndrome

Science (American Association for the Advancement of Science), 2019-12, Vol.366 (6472), p.1486-1492

2019

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Structural implications of hERG K+ channel block by a high-affinity minimally structured blocker

The Journal of biological chemistry, 2018-05, Vol.293 (18), p.7040-7057

2018

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Identification of WP1066, an inhibitor of JAK2 and STAT3, as a K V 1.3 potassium channel blocker

British journal of pharmacology, 2021-07, Vol.178 (13), p.2617-2631

2021

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Neural KCNQ (Kv7) channels

British journal of pharmacology, 2009-04, Vol.156 (8), p.1185-1195

2009

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Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

Science (American Association for the Advancement of Science), 2010-01, Vol.327 (5963), p.348-351

2010

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A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis

Proceedings of the National Academy of Sciences - PNAS, 2023-01, Vol.120 (2), p.e2211977120-e2211977120

2023

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Scorpion Potassium Channel-blocking Defensin Highlights a Functional Link with Neurotoxin

The Journal of biological chemistry, 2016-03, Vol.291 (13), p.7097-7106

2016

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Facilitation of I Kr current by some hERG channel blockers suppresses early afterdepolarizations

The Journal of general physiology, 2019-02, Vol.151 (2), p.214-230

2019

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Crystal Structure of the Human K2P TRAAK, a Lipid-and Mechano-Sensitive K⁺ Ion Channel

Science (American Association for the Advancement of Science), 2012-01, Vol.335 (6067), p.436-441

2012

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Low intravascular pressure activates endothelial cell TRPV4 channels, local Ca²⁺ events, and IKCₐ channels, reducing arteriolar tone

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (44), p.18174-18179

2012

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Targeting two‐pore domain K+ channels TREK‐1 and TASK‐3 for the treatment of depression: a new therapeutic concept

British journal of pharmacology, 2015-02, Vol.172 (3), p.771-784

2015

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Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of K ATP Channel Blockers

Diabetes (New York, N.Y.), 2018-11, Vol.67 (11), p.2239

2018

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Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism

The Journal of general physiology, 2014-11, Vol.144 (5), p.415-440

2014

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Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

The New England journal of medicine, 2010-10, Vol.363 (15), p.1397-1409

2010

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Novel cell-free high-throughput screening method for pharmacological tools targeting K⁺ channels

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (20), p.5748-5753

2016

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Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers

Blood, 2011-01, Vol.117 (3), p.902-914

2011

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Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels

The Journal of general physiology, 2023-02, Vol.155 (2), p.1

2023

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Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 Å Resolution

Science (American Association for the Advancement of Science), 2009-12, Vol.326 (5960), p.1668-1674

2009

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Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

Nature, 2006-04, Vol.440 (7086), p.959-962

2006

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Multiple targets for flecainide action: implications for cardiac arrhythmogenesis

British journal of pharmacology, 2018-04, Vol.175 (8), p.1260-1278

2018

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Purlisin, a toxin‐like defensin derived from clinical pathogenic fungus Purpureocillium lilacinum with both antimicrobial and potassium channel inhibitory activities

The FASEB journal, 2020-11, Vol.34 (11), p.15093-15107

2020

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Designer and natural peptide toxin blockers of the KcsA potassium channel identified by phage display

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (50), p.E7013-E7021

2015

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Understanding and improving photo‐control of ion channels in nociceptors with azobenzene photo‐switches

British journal of pharmacology, 2018-06, Vol.175 (12), p.2296-2311

2018

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Computational assessment of drug‐induced effects on the electrocardiogram: from ion channel to body surface potentials

British journal of pharmacology, 2013-02, Vol.168 (3), p.718-733

2013

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Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanism

Potassium channel dysfunction in human neuronal models of Angelman syndrome

Structural implications of hERG K+ channel block by a high-affinity minimally structured blocker

Identification of WP1066, an inhibitor of JAK2 and STAT3, as a K V 1.3 potassium channel blocker

Neural KCNQ (Kv7) channels

Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis

Scorpion Potassium Channel-blocking Defensin Highlights a Functional Link with Neurotoxin

Facilitation of I Kr current by some hERG channel blockers suppresses early afterdepolarizations

Crystal Structure of the Human K2P TRAAK, a Lipid-and Mechano-Sensitive K⁺ Ion Channel

Low intravascular pressure activates endothelial cell TRPV4 channels, local Ca²⁺ events, and IKCₐ channels, reducing arteriolar tone

Targeting two‐pore domain K+ channels TREK‐1 and TASK‐3 for the treatment of depression: a new therapeutic concept

Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of K ATP Channel Blockers

Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

Novel cell-free high-throughput screening method for pharmacological tools targeting K⁺ channels

Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers

Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels

Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 Å Resolution

Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

Multiple targets for flecainide action: implications for cardiac arrhythmogenesis

Purlisin, a toxin‐like defensin derived from clinical pathogenic fungus Purpureocillium lilacinum with both antimicrobial and potassium channel inhibitory activities

Designer and natural peptide toxin blockers of the KcsA potassium channel identified by phage display

Understanding and improving photo‐control of ion channels in nociceptors with azobenzene photo‐switches

Computational assessment of drug‐induced effects on the electrocardiogram: from ion channel to body surface potentials

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