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Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer

Cancer letters, 2015-04, Vol.359 (1), p.47-56

2015

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Mechanisms of Autophagy Initiation

Annual review of biochemistry, 2017-06, Vol.86 (1), p.225-244

2017

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Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses

Immunity (Cambridge, Mass.), 2021-05, Vol.54 (5), p.976-987.e7

2021

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The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4507

2020

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Insulin Enhances Gene Expression of Midnolin , a Novel Genetic Risk Factor for Parkinson's Disease, via Extracellular Signal-Regulated Kinase, Phosphoinositide 3-Kinase and Multiple Transcription Factors in SH-SY5Y Cells

The Journal of pharmacology and experimental therapeutics, 2022-05, Vol.381 (2), p.68-78

2022

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Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression

Cancer discovery, 2016-08, Vol.6 (8), p.870-885

2016

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Inhibition of Phosphatidylinositol 3-kinase (PI3K) Signaling Synergistically Potentiates Antitumor Efficacy of Paclitaxel and Overcomes Paclitaxel-Mediated Resistance in Cervical Cancer

International journal of molecular sciences, 2019-07, Vol.20 (14), p.3383

2019

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Phosphatidylinositol 3-kinase p110δ drives intestinal fibrosis in SHIP deficiency

Mucosal immunology, 2019-09, Vol.12 (5), p.1187-1200

2019

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Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

Nature cell biology, 2018-03, Vol.20 (3), p.307-319

2018

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Molecular Characterization of a B Cell Adaptor for Phosphoinositide 3-Kinase Homolog in Lamprey ( Lampetra japonica ) and Its Function in the Immune Response

International journal of molecular sciences, 2022-11, Vol.23 (22), p.14449

2022

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Class 3 phosphoinositide 3‐kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity

Acta Physiologica, 2022-05, Vol.235 (1), p.e13793-n/a

2022

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The interleukin-enhanced binding factor 3-mediated inhibition of nitric oxide production via phosphoinositide 3-kinase/protein kinase B pathway contributes to central cardiovascular regulation in the rostral ventrolateral medulla in hypertension

American journal of physiology. Regulatory, integrative and comparative physiology, 2022-12, Vol.323 (6), p.R861-R874

2022

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Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

Aging (Albany, NY.), 2020-04, Vol.12 (8), p.6852-6864

2020

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The interleukin-33-mediated inhibition of expression of two key genes implicated in atherosclerosis in human macrophages requires MAP kinase, phosphoinositide 3-kinase and nuclear factor-κB signaling pathways

Scientific reports, 2019-08, Vol.9 (1), p.11317-12, Article 11317

2019

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Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish

Nature communications, 2018-07, Vol.9 (1), p.2639-13, Article 2639

2018

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Exogenous Therapeutics of Microrna-29a Attenuates Development of Hepatic Fibrosis in Cholestatic Animal Model through Regulation of Phosphoinositide 3-Kinase p85 Alpha

International journal of molecular sciences, 2020-05, Vol.21 (10), p.3636

2020

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Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to liver injury

Gut, 2017-06, Vol.66 (6), p.1123-1137

2017

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PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (27), p.7095-7100

2017

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Taurine stimulates protein synthesis and proliferation of C2C12 myoblast cells through the PI3K-ARID4B-mTOR pathway

British journal of nutrition, 2022-11, Vol.128 (10), p.1875-1886

2022

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Bioinformatics identification of miR‐514b‐5p promotes NSCLC progression and induces PI3K/AKT and p38 pathways by targeting small glutamine‐rich tetratricopeptide repeat‐containing protein beta

The FEBS journal, 2023-02, Vol.290 (4), p.1134-1150

2023

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microRNA‐186 inhibition of PI3K–AKT pathway via SPP1 inhibits chondrocyte apoptosis in mice with osteoarthritis

Journal of cellular physiology, 2019-05, Vol.234 (5), p.6042-6053

2019

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Diosgenin, a steroidal saponin, inhibits migration and invasion of human prostate cancer PC-3 cells by reducing matrix metalloproteinases expression

PloS one, 2011-05, Vol.6 (5), p.e20164

2011

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Discovery of a small molecule agonist of phosphatidylinositol 3-kinase p110α that reactivates latent HIV-1

PloS one, 2014, Vol.9 (1), p.e84964-e84964

2014

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Knockdown of anti-silencing function 1B histone chaperone induces cell apoptosis via repressing PI3K/Akt pathway in prostate cancer

International journal of oncology, 2018-11, Vol.53 (5), p.2056-2066

2018

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Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide‐induced premature ovarian failure

Basic & clinical pharmacology & toxicology, 2022-02, Vol.130 (2), p.240-253

2022

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Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer

Mechanisms of Autophagy Initiation

Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses

The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

Insulin Enhances Gene Expression of Midnolin , a Novel Genetic Risk Factor for Parkinson's Disease, via Extracellular Signal-Regulated Kinase, Phosphoinositide 3-Kinase and Multiple Transcription Factors in SH-SY5Y Cells

Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression

Inhibition of Phosphatidylinositol 3-kinase (PI3K) Signaling Synergistically Potentiates Antitumor Efficacy of Paclitaxel and Overcomes Paclitaxel-Mediated Resistance in Cervical Cancer

Phosphatidylinositol 3-kinase p110δ drives intestinal fibrosis in SHIP deficiency

Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

Molecular Characterization of a B Cell Adaptor for Phosphoinositide 3-Kinase Homolog in Lamprey ( Lampetra japonica ) and Its Function in the Immune Response

Class 3 phosphoinositide 3‐kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity

The interleukin-enhanced binding factor 3-mediated inhibition of nitric oxide production via phosphoinositide 3-kinase/protein kinase B pathway contributes to central cardiovascular regulation in the rostral ventrolateral medulla in hypertension

Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

The interleukin-33-mediated inhibition of expression of two key genes implicated in atherosclerosis in human macrophages requires MAP kinase, phosphoinositide 3-kinase and nuclear factor-κB signaling pathways

Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish

Exogenous Therapeutics of Microrna-29a Attenuates Development of Hepatic Fibrosis in Cholestatic Animal Model through Regulation of Phosphoinositide 3-Kinase p85 Alpha

Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to liver injury

PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α

Taurine stimulates protein synthesis and proliferation of C2C12 myoblast cells through the PI3K-ARID4B-mTOR pathway

Bioinformatics identification of miR‐514b‐5p promotes NSCLC progression and induces PI3K/AKT and p38 pathways by targeting small glutamine‐rich tetratricopeptide repeat‐containing protein beta

microRNA‐186 inhibition of PI3K–AKT pathway via SPP1 inhibits chondrocyte apoptosis in mice with osteoarthritis

Diosgenin, a steroidal saponin, inhibits migration and invasion of human prostate cancer PC-3 cells by reducing matrix metalloproteinases expression

Discovery of a small molecule agonist of phosphatidylinositol 3-kinase p110α that reactivates latent HIV-1

Knockdown of anti-silencing function 1B histone chaperone induces cell apoptosis via repressing PI3K/Akt pathway in prostate cancer

Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide‐induced premature ovarian failure

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