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Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway

Bioengineered, 2022-03, Vol.13 (3), p.6794-6806

2022

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Galangin alleviates rheumatoid arthritis in rats by downregulating the phosphatidylinositol 3-kinase/protein kinase B signaling pathway

Bioengineered, 2022-04, Vol.13 (4), p.11192-11201

2022

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Gastrodin protects retinal ganglion cells from ischemic injury by activating phosphatidylinositol 3-kinase/protein kinase B/nuclear factor erythroid 2-related factor 2 (PI3K/AKT/Nrf2) signaling pathway

Bioengineered, 2022-05, Vol.13 (5), p.12625-12636

2022

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Curcumin alleviates rheumatoid arthritis progression through the phosphatidylinositol 3-kinase/protein kinase B pathway: an in vitro and in vivo study

Bioengineered, 2022-05, Vol.13 (5), p.12899-12911

2022

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Inhibition of integrin subunit alpha 11 restrains gastric cancer progression through phosphatidylinositol 3-kinase/Akt pathway

Bioengineered, 2021-12, Vol.12 (2), p.11909-11921

2021

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Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

Bioscience, biotechnology, and biochemistry, 2023-11, Vol.87 (12), p.1462-1469

2023

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Sequential conversion of PtdIns3P to PtdIns(3,5)P 2 via endosome maturation couples nutrient signaling to lysosome reformation and basal autophagy

Autophagy, 2023-04, Vol.19 (4), p.1365-1367

2023

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Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against osteosarcoma

Cancer biology & therapy, 2015-01, Vol.16 (4), p.602-609

2015

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MicroRNA miR-23b-3p promotes osteosarcoma by targeting ventricular zone expressed PH domain-containing 1 (VEPH1)/phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) pathway

Bioengineered, 2021-12, Vol.12 (2), p.12568-12582

2021

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MicroRNA-631 deriving from bone marrow mesenchymal stem cell exosomes facilitates the malignant behavior of non-small cell lung cancer via modulating the E2F family of transcription factor 2/phosphatidylinositol 3-kinase/Akt signaling pathway

Bioengineered, 2022-04, Vol.13 (4), p.8382-8395

2022

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Overexpression of microRNA-145 enhanced docetaxel sensitivity in breast cancer cells via inactivation of protein kinase B gamma-mediated phosphoinositide 3-kinase -protein kinase B pathway

Bioengineered, 2022-04, Vol.13 (4), p.11310-11320

2022

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LEM domain containing 1 (LEMD1) transcriptionally activated by SRY-related high-mobility-group box 4 (SOX4) accelerates the progression of colon cancer by upregulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway

Bioengineered, 2022-04, Vol.13 (4), p.8087-8100

2022

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Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway

Bioengineered, 2021-12, Vol.12 (2), p.12227-12235

2021

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Quercetin alleviates chronic renal failure by targeting the PI3k/Akt pathway

Bioengineered, 2021-01, Vol.12 (1), p.6538-6558

2021

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Up-regulation of LINC00619 promotes apoptosis and inhibits proliferation, migration and invasion while promoting apoptosis of osteosarcoma cells through inactivation of the HGF-mediated PI3K-Akt signalling pathway

Epigenetics, 2022-02, Vol.17 (2), p.147-160

2022

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Modulation of the PI3K/Akt/mTOR signaling pathway by probiotics as a fruitful target for orchestrating the immune response

Gut microbes, 2021-01, Vol.13 (1), p.1-17

2021

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miR-451 suppresses EMT and metastasis in glioma cells

Cell cycle (Georgetown, Tex.), 2021-07, Vol.20 (13), p.1270-1278

2021

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A pivotal role of phosphatidylinositol 3-kinase in delaying of methyl jasmonate-induced leaf senescence

Plant signaling & behavior, 2016-06, Vol.11 (6), p.e1147642-e1147642

2016

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TGF-β is associated with poor prognosis and promotes osteosarcoma progression via PI3K/Akt pathway activation

Cell cycle (Georgetown, Tex.), 2020-09, Vol.19 (18), p.2327-2339

2020

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Cross-talk between Rho GTPases and PI3K in the neutrophil

Small GTPases, 2019-05, Vol.10 (3), p.187-195

2019

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Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway

Bioengineered, 2022-04, Vol.13 (4), p.8850-8865

2022

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VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2

Cell cycle (Georgetown, Tex.), 2018-01, Vol.17 (2), p.225-239

2018

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Salvianolic acid A (Sal A) suppresses malignant progression of glioma and enhances temozolomide (TMZ) sensitivity via repressing transgelin-2 (TAGLN2) mediated phosphatidylinositol-3-kinase (PI3K) / protein kinase B (Akt) pathway

Bioengineered, 2022-05, Vol.13 (5), p.11646-11655

2022

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Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3′-kinase/protein kinase B/mammalian target of rapamycin pathway

Bioengineered, 2022-04, Vol.13 (4), p.10047-10060

2022

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ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition

Cancer biology & therapy, 2014-03, Vol.15 (3), p.317-328

2014

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Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway

Galangin alleviates rheumatoid arthritis in rats by downregulating the phosphatidylinositol 3-kinase/protein kinase B signaling pathway

Gastrodin protects retinal ganglion cells from ischemic injury by activating phosphatidylinositol 3-kinase/protein kinase B/nuclear factor erythroid 2-related factor 2 (PI3K/AKT/Nrf2) signaling pathway

Curcumin alleviates rheumatoid arthritis progression through the phosphatidylinositol 3-kinase/protein kinase B pathway: an in vitro and in vivo study

Inhibition of integrin subunit alpha 11 restrains gastric cancer progression through phosphatidylinositol 3-kinase/Akt pathway

Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

Sequential conversion of PtdIns3P to PtdIns(3,5)P 2 via endosome maturation couples nutrient signaling to lysosome reformation and basal autophagy

Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against osteosarcoma

MicroRNA miR-23b-3p promotes osteosarcoma by targeting ventricular zone expressed PH domain-containing 1 (VEPH1)/phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) pathway

MicroRNA-631 deriving from bone marrow mesenchymal stem cell exosomes facilitates the malignant behavior of non-small cell lung cancer via modulating the E2F family of transcription factor 2/phosphatidylinositol 3-kinase/Akt signaling pathway

Overexpression of microRNA-145 enhanced docetaxel sensitivity in breast cancer cells via inactivation of protein kinase B gamma-mediated phosphoinositide 3-kinase -protein kinase B pathway

LEM domain containing 1 (LEMD1) transcriptionally activated by SRY-related high-mobility-group box 4 (SOX4) accelerates the progression of colon cancer by upregulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway

Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway

Quercetin alleviates chronic renal failure by targeting the PI3k/Akt pathway

Up-regulation of LINC00619 promotes apoptosis and inhibits proliferation, migration and invasion while promoting apoptosis of osteosarcoma cells through inactivation of the HGF-mediated PI3K-Akt signalling pathway

Modulation of the PI3K/Akt/mTOR signaling pathway by probiotics as a fruitful target for orchestrating the immune response

miR-451 suppresses EMT and metastasis in glioma cells

A pivotal role of phosphatidylinositol 3-kinase in delaying of methyl jasmonate-induced leaf senescence

TGF-β is associated with poor prognosis and promotes osteosarcoma progression via PI3K/Akt pathway activation

Cross-talk between Rho GTPases and PI3K in the neutrophil

Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway

VEGFC/VEGFR3 Signaling Regulates Mouse Spermatogonial Cell Proliferation via the Activation of AKT/MAPK and Cyclin D1 Pathway and Mediates the Apoptosis by affecting Caspase 3/9 and Bcl-2

Salvianolic acid A (Sal A) suppresses malignant progression of glioma and enhances temozolomide (TMZ) sensitivity via repressing transgelin-2 (TAGLN2) mediated phosphatidylinositol-3-kinase (PI3K) / protein kinase B (Akt) pathway

Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3′-kinase/protein kinase B/mammalian target of rapamycin pathway

ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition

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