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Duvelisib for the treatment of chronic lymphocytic leukemia

Expert opinion on pharmacotherapy, 2020-07, Vol.21 (11), p.1299-1309

2020

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Management of adverse events associated with idelalisib treatment: expert panel opinion

Leukemia & lymphoma, 2015-10, Vol.56 (10), p.2779-2786

2015

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Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway

Bioengineered, 2022-03, Vol.13 (3), p.6794-6806

2022

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Targeting AKT for cancer therapy

Expert opinion on investigational drugs, 2019-11, Vol.28 (11), p.977-988

2019

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Galangin alleviates rheumatoid arthritis in rats by downregulating the phosphatidylinositol 3-kinase/protein kinase B signaling pathway

Bioengineered, 2022-04, Vol.13 (4), p.11192-11201

2022

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Curcumin alleviates rheumatoid arthritis progression through the phosphatidylinositol 3-kinase/protein kinase B pathway: an in vitro and in vivo study

Bioengineered, 2022-05, Vol.13 (5), p.12899-12911

2022

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Inhibition of integrin subunit alpha 11 restrains gastric cancer progression through phosphatidylinositol 3-kinase/Akt pathway

Bioengineered, 2021-12, Vol.12 (2), p.11909-11921

2021

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New phosphatidylinositol 3-kinase inhibitors for cancer

Expert opinion on investigational drugs, 2011-04, Vol.20 (4), p.507-518

2011

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Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

Bioscience, biotechnology, and biochemistry, 2023-11, Vol.87 (12), p.1462-1469

2023

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Gastrodin protects retinal ganglion cells from ischemic injury by activating phosphatidylinositol 3-kinase/protein kinase B/nuclear factor erythroid 2-related factor 2 (PI3K/AKT/Nrf2) signaling pathway

Bioengineered, 2022-05, Vol.13 (5), p.12625-12636

2022

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Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against osteosarcoma

Cancer biology & therapy, 2015-01, Vol.16 (4), p.602-609

2015

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Sequential conversion of PtdIns3P to PtdIns(3,5)P 2 via endosome maturation couples nutrient signaling to lysosome reformation and basal autophagy

Autophagy, 2023-04, Vol.19 (4), p.1365-1367

2023

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MicroRNA-631 deriving from bone marrow mesenchymal stem cell exosomes facilitates the malignant behavior of non-small cell lung cancer via modulating the E2F family of transcription factor 2/phosphatidylinositol 3-kinase/Akt signaling pathway

Bioengineered, 2022-04, Vol.13 (4), p.8382-8395

2022

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MicroRNA miR-23b-3p promotes osteosarcoma by targeting ventricular zone expressed PH domain-containing 1 (VEPH1)/phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) pathway

Bioengineered, 2021-12, Vol.12 (2), p.12568-12582

2021

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Overexpression of microRNA-145 enhanced docetaxel sensitivity in breast cancer cells via inactivation of protein kinase B gamma-mediated phosphoinositide 3-kinase -protein kinase B pathway

Bioengineered, 2022-04, Vol.13 (4), p.11310-11320

2022

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LEM domain containing 1 (LEMD1) transcriptionally activated by SRY-related high-mobility-group box 4 (SOX4) accelerates the progression of colon cancer by upregulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway

Bioengineered, 2022-04, Vol.13 (4), p.8087-8100

2022

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Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway

Bioengineered, 2021-12, Vol.12 (2), p.12227-12235

2021

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Staying alive: Metabolic adaptations to quiescence

Cell cycle (Georgetown, Tex.), 2012-05, Vol.11 (9), p.1680-1696

2012

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Quercetin alleviates chronic renal failure by targeting the PI3k/Akt pathway

Bioengineered, 2021-01, Vol.12 (1), p.6538-6558

2021

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Up-regulation of LINC00619 promotes apoptosis and inhibits proliferation, migration and invasion while promoting apoptosis of osteosarcoma cells through inactivation of the HGF-mediated PI3K-Akt signalling pathway

Epigenetics, 2022-02, Vol.17 (2), p.147-160

2022

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Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1104-1114

2021

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Modulation of the PI3K/Akt/mTOR signaling pathway by probiotics as a fruitful target for orchestrating the immune response

Gut microbes, 2021-01, Vol.13 (1), p.1-17

2021

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Targeting phosphatidylinositol 3-kinase signaling in acute myelogenous leukemia

Expert opinion on therapeutic targets, 2013-08, Vol.17 (8), p.921-936

2013

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Quercetin Regresses Dalton's Lymphoma Growth via Suppression of PI3K/AKT Signaling Leading to Upregulation of p53 and Decrease in Energy Metabolism

Nutrition and cancer, 2015-02, Vol.67 (2), p.354-363

2015

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Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke

Pharmaceutical biology, 2022-12, Vol.60 (1), p.119-130

2022

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Duvelisib for the treatment of chronic lymphocytic leukemia

Management of adverse events associated with idelalisib treatment: expert panel opinion

Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway

Targeting AKT for cancer therapy

Galangin alleviates rheumatoid arthritis in rats by downregulating the phosphatidylinositol 3-kinase/protein kinase B signaling pathway

Curcumin alleviates rheumatoid arthritis progression through the phosphatidylinositol 3-kinase/protein kinase B pathway: an in vitro and in vivo study

Inhibition of integrin subunit alpha 11 restrains gastric cancer progression through phosphatidylinositol 3-kinase/Akt pathway

New phosphatidylinositol 3-kinase inhibitors for cancer

Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

Gastrodin protects retinal ganglion cells from ischemic injury by activating phosphatidylinositol 3-kinase/protein kinase B/nuclear factor erythroid 2-related factor 2 (PI3K/AKT/Nrf2) signaling pathway

Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against osteosarcoma

Sequential conversion of PtdIns3P to PtdIns(3,5)P 2 via endosome maturation couples nutrient signaling to lysosome reformation and basal autophagy

MicroRNA-631 deriving from bone marrow mesenchymal stem cell exosomes facilitates the malignant behavior of non-small cell lung cancer via modulating the E2F family of transcription factor 2/phosphatidylinositol 3-kinase/Akt signaling pathway

MicroRNA miR-23b-3p promotes osteosarcoma by targeting ventricular zone expressed PH domain-containing 1 (VEPH1)/phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) pathway

Overexpression of microRNA-145 enhanced docetaxel sensitivity in breast cancer cells via inactivation of protein kinase B gamma-mediated phosphoinositide 3-kinase -protein kinase B pathway

LEM domain containing 1 (LEMD1) transcriptionally activated by SRY-related high-mobility-group box 4 (SOX4) accelerates the progression of colon cancer by upregulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway

Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway

Staying alive: Metabolic adaptations to quiescence

Quercetin alleviates chronic renal failure by targeting the PI3k/Akt pathway

Up-regulation of LINC00619 promotes apoptosis and inhibits proliferation, migration and invasion while promoting apoptosis of osteosarcoma cells through inactivation of the HGF-mediated PI3K-Akt signalling pathway

Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway

Modulation of the PI3K/Akt/mTOR signaling pathway by probiotics as a fruitful target for orchestrating the immune response

Targeting phosphatidylinositol 3-kinase signaling in acute myelogenous leukemia

Quercetin Regresses Dalton's Lymphoma Growth via Suppression of PI3K/AKT Signaling Leading to Upregulation of p53 and Decrease in Energy Metabolism

Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke

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