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Class I PI3K-mediated Akt and ERK signals play a critical role in FcεRI-induced degranulation in mast cells

International immunology, 2013-04, Vol.25 (4), p.215-220

2013

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Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3‑Kinase/Akt Phosphorylation

Journal of medicinal chemistry, 2022-05, Vol.65 (10), p.7399-7413

2022

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Quercetin inhibited epithelial mesenchymal transition in diabetic rats, high-glucose-cultured lens, and SRA01/04 cells through transforming growth factor-β2/phosphoinositide 3-kinase/Akt pathway

Molecular and cellular endocrinology, 2017-09, Vol.452, p.44-56

2017

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Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice

Gastroenterology (New York, N.Y. 1943), 2015-12, Vol.149 (7), p.1884-1895.e4

2015

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The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12), p.2269-2280

2022

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The Role of the LY294002 - A Non-Selective Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) Pathway- in Cell Survival and Proliferation in Cell Line SCC-25

Asian Pacific Journal of Cancer Prevention, 2019-11, Vol.20 (11), p.3377-3383

2019

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Qizhi Jiangtang capsule activates podocyte autophagy in diabetic kidney disease by inhibiting phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathways

Journal of traditional Chinese medicine, 2023-08, Vol.43 (4), p.667-675

2023

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Insulin promotes macrophage phenotype transition through PI3K/Akt and PPAR‐γ signaling during diabetic wound healing

Journal of cellular physiology, 2019-04, Vol.234 (4), p.4217-4231

2019

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Curcumin alleviates rheumatoid arthritis progression through the phosphatidylinositol 3-kinase/protein kinase B pathway: an in vitro and in vivo study

Bioengineered, 2022-05, Vol.13 (5), p.12899-12911

2022

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Maximising the potential of AKT inhibitors as anti-cancer treatments

Pharmacology & therapeutics (Oxford), 2017-04, Vol.172, p.101-115

2017

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Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling

Blood, 2012-01, Vol.119 (3), p.847-856

2012

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Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells

Nature immunology, 2013-02, Vol.14 (2), p.162-171

2013

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Gastrodin protects retinal ganglion cells from ischemic injury by activating phosphatidylinositol 3-kinase/protein kinase B/nuclear factor erythroid 2-related factor 2 (PI3K/AKT/Nrf2) signaling pathway

Bioengineered, 2022-05, Vol.13 (5), p.12625-12636

2022

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Report of a Chinese Cohort with Activated Phosphoinositide 3-Kinase δ Syndrome

Journal of clinical immunology, 2018-11, Vol.38 (8), p.854-863

2018

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Synaptotagmin 12 (SYT12) Gene Expression Promotes Cell Proliferation and Progression of Lung Adenocarcinoma and Involves the Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

Medical science monitor, 2020-02, Vol.26, p.e920351-e920351

2020

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A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion

The Journal of biological chemistry, 2019-03, Vol.294 (12), p.4621-4633

2019

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Structure of the Human TELO2-TTI1-TTI2 Complex

Journal of molecular biology, 2022-01, Vol.434 (2), p.167370-167370, Article 167370

2022

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Moxibustion's protective role against atherosclerosis: Inhibition of Ca 2+ overload-triggered oxidative stress and inflammatory response via P2Y12/PI3K/AKT pathway

Environmental toxicology, 2024-01, Vol.39 (1), p.228-237

2024

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Sequential conversion of PtdIns3P to PtdIns(3,5)P 2 via endosome maturation couples nutrient signaling to lysosome reformation and basal autophagy

Autophagy, 2023-04, Vol.19 (4), p.1365-1367

2023

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p110α and p110β isoforms of PI3K signaling: are they two sides of the same coin?

FEBS letters, 2016-09, Vol.590 (18), p.3071-3082

2016

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Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity

Biochemical journal, 2015-07, Vol.469 (1), p.59-69

2015

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Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy

eLife, 2021-09, Vol.10

2021

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CD19 Is Internalized Together with IgM in Proportion to B Cell Receptor Stimulation and Is Modulated by Phosphatidylinositol 3-Kinase in Bone Marrow Immature B Cells

ImmunoHorizons, 2023-01, Vol.7 (1), p.49-63

2023

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Blocking the phosphatidylinositol 3-kinase pathway inhibits neuregulin-1-mediated rescue of neurotoxicity induced by Aβ1-42

Journal of pharmacy and pharmacology, 2016-08, Vol.68 (8), p.1021-1029

2016

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Bauerane Induces S-Phase Cell Cycle Arrest, Apoptosis, and Inhibition of Proliferation of A549 Human Lung Cancer Cells Through the Phosphoinositide 3-Kinase (PI3K)/AKT and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway

Medical science monitor, 2020-02, Vol.26, p.e919558-e919558-7

2020

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Class I PI3K-mediated Akt and ERK signals play a critical role in FcεRI-induced degranulation in mast cells

Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3‑Kinase/Akt Phosphorylation

Quercetin inhibited epithelial mesenchymal transition in diabetic rats, high-glucose-cultured lens, and SRA01/04 cells through transforming growth factor-β2/phosphoinositide 3-kinase/Akt pathway

Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice

The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation

The Role of the LY294002 - A Non-Selective Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) Pathway- in Cell Survival and Proliferation in Cell Line SCC-25

Qizhi Jiangtang capsule activates podocyte autophagy in diabetic kidney disease by inhibiting phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathways

Insulin promotes macrophage phenotype transition through PI3K/Akt and PPAR‐γ signaling during diabetic wound healing

Curcumin alleviates rheumatoid arthritis progression through the phosphatidylinositol 3-kinase/protein kinase B pathway: an in vitro and in vivo study

Maximising the potential of AKT inhibitors as anti-cancer treatments

Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling

Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells

Gastrodin protects retinal ganglion cells from ischemic injury by activating phosphatidylinositol 3-kinase/protein kinase B/nuclear factor erythroid 2-related factor 2 (PI3K/AKT/Nrf2) signaling pathway

Report of a Chinese Cohort with Activated Phosphoinositide 3-Kinase δ Syndrome

Synaptotagmin 12 (SYT12) Gene Expression Promotes Cell Proliferation and Progression of Lung Adenocarcinoma and Involves the Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion

Structure of the Human TELO2-TTI1-TTI2 Complex

Moxibustion's protective role against atherosclerosis: Inhibition of Ca 2+ overload-triggered oxidative stress and inflammatory response via P2Y12/PI3K/AKT pathway

Sequential conversion of PtdIns3P to PtdIns(3,5)P 2 via endosome maturation couples nutrient signaling to lysosome reformation and basal autophagy

p110α and p110β isoforms of PI3K signaling: are they two sides of the same coin?

Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity

Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy

CD19 Is Internalized Together with IgM in Proportion to B Cell Receptor Stimulation and Is Modulated by Phosphatidylinositol 3-Kinase in Bone Marrow Immature B Cells

Blocking the phosphatidylinositol 3-kinase pathway inhibits neuregulin-1-mediated rescue of neurotoxicity induced by Aβ1-42

Bauerane Induces S-Phase Cell Cycle Arrest, Apoptosis, and Inhibition of Proliferation of A549 Human Lung Cancer Cells Through the Phosphoinositide 3-Kinase (PI3K)/AKT and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway

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