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Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

Nature communications, 2024-03, Vol.15 (1), p.2612-2612

2024

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The PI3K/AKT/mTOR signaling pathway in breast cancer: Review of clinical trials and latest advances

Cell biochemistry and function, 2024-04, Vol.42 (3), p.e3998-e3998

2024

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A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia

Journal of ethnopharmacology, 2024-06, Vol.328, p.118117-118117, Article 118117

2024

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Combination of ethyl acetate fraction from Calotropis gigantea stem bark and sorafenib induces apoptosis in HepG2 cells

PloS one, 2024-03, Vol.19 (3), p.e0300051-e0300051

2024

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Effect of miR-1297 on Kidney Injury in Rats with Diabetic Nephropathy through the PTEN/PI3K/AKT Pathway

Archivos españoles de urología, 2024-03, Vol.77 (2), p.183-192

2024

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Tanshinone IIA Regulates Synaptic Plasticity in Mg 2+ -Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway

Journal of integrative neuroscience, 2024-03, Vol.23 (3), p.61

2024

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Kinetochore scaffold 1 downregulation suppressed the development of non-small cell lung cancer by inactivating the phosphatidylinositol 3 kinase/protein kinase B (AKT)/nuclear factor-kappa B pathway

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2024-02, Vol.75 (1)

2024

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A Phase I Study of the Oral Dual-Acting Pan-PI3K/mTOR Inhibitor Bimiralisib in Patients with Advanced Solid Tumors

Cancers, 2024-03, Vol.16 (6), p.1137

2024

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Regulation of inflammatory response by LINC00346 via miR-25-3p-mediated modulation of the PTEN/PI3K/AKT/NF-κB pathway

Biochemical and biophysical research communications, 2024-05, Vol.709, p.149828-149828, Article 149828

2024

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DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level

Toxicology in vitro, 2024-05, Vol.97, p.105809-105809, Article 105809

2024

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Optimal targeting of PI3K-AKT and mTOR in advanced oestrogen receptor-positive breast cancer

The lancet oncology, 2024-04, Vol.25 (4), p.e139-e151

2024

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Excessive Tryptophan and Phenylalanine Induced Pancreatic Injury and Glycometabolism Disorder in Grower-finisher Pigs

The Journal of nutrition, 2024-04, Vol.154 (4), p.1333-1346

2024

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Nuciferine reduces vascular leakage and improves cardiac function in acute myocardial infarction by regulating the PI3K/AKT pathway

Scientific reports, 2024-03, Vol.14 (1), p.7086-7086

2024

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Gadd45g insufficiency drives the pathogenesis of myeloproliferative neoplasms

Nature communications, 2024-04, Vol.15 (1), p.2989-2989

2024

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The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts

Scientific reports, 2024-03, Vol.14 (1), p.7559-7559

2024

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Knockdown of NCAPD3 inhibits the tumorigenesis of non-small cell lung cancer by regulation of the PI3K/Akt pathway

BMC cancer, 2024-04, Vol.24 (1), p.408-408

2024

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Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis

Respiratory research, 2024-04, Vol.25 (1), p.160-160

2024

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Mechanisms underlying LncRNA SNHG1 regulation of Alzheimer's disease involve DNA methylation

Journal of Toxicology and Environmental Health, Part A, 2024-05, Vol.87 (10), p.428-435

2024

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Differential prognostic values of the three AKT isoforms in acute myeloid leukemia

Scientific reports, 2024-03, Vol.14 (1), p.7070-7070

2024

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USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway

Cell death & disease, 2024-03, Vol.15 (3), p.235-235

2024

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Osteopontin promotes tumor growth and metastasis and GPX4-mediated anti-lipid peroxidation in triple-negative breast cancer by activating the PI3k/Akt/mTOR pathway

Journal of cancer research and clinical oncology, 2024-03, Vol.150 (3), p.155-155

2024

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PQR309, a dual PI3K/mTOR inhibitor, synergizes with gemcitabine by impairing the GSK-3β and STAT3/HSP60 signaling pathways to treat nasopharyngeal carcinoma

Cell death & disease, 2024-03, Vol.15 (3), p.237-237

2024

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The involvement of Akt, mTOR, and S6K in the in vivo effect of IGF-1 on the regulation of rat cardiac Na+/K+-ATPase

Molecular biology reports, 2024-04, Vol.51 (1), p.517-517

2024

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The protective effect and mechanism of glycosides of cistanche deserticola on rats in middle cerebral artery occlusion (MCAO) model

Journal of Toxicology and Environmental Health, Part A, 2024-05, Vol.87 (10), p.448-456

2024

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Targeting myocardial inflammation: investigating the therapeutic potential of atrial natriuretic peptide in atrial fibrosis

Molecular biology reports, 2024-04, Vol.51 (1), p.506-506

2024

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Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

The PI3K/AKT/mTOR signaling pathway in breast cancer: Review of clinical trials and latest advances

A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia

Combination of ethyl acetate fraction from Calotropis gigantea stem bark and sorafenib induces apoptosis in HepG2 cells

Effect of miR-1297 on Kidney Injury in Rats with Diabetic Nephropathy through the PTEN/PI3K/AKT Pathway

Tanshinone IIA Regulates Synaptic Plasticity in Mg 2+ -Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway

Kinetochore scaffold 1 downregulation suppressed the development of non-small cell lung cancer by inactivating the phosphatidylinositol 3 kinase/protein kinase B (AKT)/nuclear factor-kappa B pathway

A Phase I Study of the Oral Dual-Acting Pan-PI3K/mTOR Inhibitor Bimiralisib in Patients with Advanced Solid Tumors

Regulation of inflammatory response by LINC00346 via miR-25-3p-mediated modulation of the PTEN/PI3K/AKT/NF-κB pathway

DMC triggers MDA-MB-231 cells apoptosis via inhibiting protective autophagy and PI3K/AKT/mTOR pathway by enhancing ROS level

Optimal targeting of PI3K-AKT and mTOR in advanced oestrogen receptor-positive breast cancer

Excessive Tryptophan and Phenylalanine Induced Pancreatic Injury and Glycometabolism Disorder in Grower-finisher Pigs

Nuciferine reduces vascular leakage and improves cardiac function in acute myocardial infarction by regulating the PI3K/AKT pathway

Gadd45g insufficiency drives the pathogenesis of myeloproliferative neoplasms

The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts

Knockdown of NCAPD3 inhibits the tumorigenesis of non-small cell lung cancer by regulation of the PI3K/Akt pathway

Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis

Mechanisms underlying LncRNA SNHG1 regulation of Alzheimer's disease involve DNA methylation

Differential prognostic values of the three AKT isoforms in acute myeloid leukemia

USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway

Osteopontin promotes tumor growth and metastasis and GPX4-mediated anti-lipid peroxidation in triple-negative breast cancer by activating the PI3k/Akt/mTOR pathway

PQR309, a dual PI3K/mTOR inhibitor, synergizes with gemcitabine by impairing the GSK-3β and STAT3/HSP60 signaling pathways to treat nasopharyngeal carcinoma

The involvement of Akt, mTOR, and S6K in the in vivo effect of IGF-1 on the regulation of rat cardiac Na+/K+-ATPase

The protective effect and mechanism of glycosides of cistanche deserticola on rats in middle cerebral artery occlusion (MCAO) model

Targeting myocardial inflammation: investigating the therapeutic potential of atrial natriuretic peptide in atrial fibrosis

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